DE69709774D1 - Substituierte benzocycloheptapyridine derivate verwendbar als farnesyl-protein transferase inhibitoren - Google Patents
Substituierte benzocycloheptapyridine derivate verwendbar als farnesyl-protein transferase inhibitorenInfo
- Publication number
- DE69709774D1 DE69709774D1 DE69709774T DE69709774T DE69709774D1 DE 69709774 D1 DE69709774 D1 DE 69709774D1 DE 69709774 T DE69709774 T DE 69709774T DE 69709774 T DE69709774 T DE 69709774T DE 69709774 D1 DE69709774 D1 DE 69709774D1
- Authority
- DE
- Germany
- Prior art keywords
- protein transferase
- farnesyl protein
- transferase inhibitors
- derivatives used
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Confectionery (AREA)
- Enzymes And Modification Thereof (AREA)
- Cosmetics (AREA)
- Indole Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71192596A | 1996-09-13 | 1996-09-13 | |
| PCT/US1997/015905 WO1998011099A1 (en) | 1996-09-13 | 1997-09-11 | Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69709774D1 true DE69709774D1 (de) | 2002-02-21 |
| DE69709774T2 DE69709774T2 (de) | 2002-08-08 |
Family
ID=24860067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69709774T Expired - Fee Related DE69709774T2 (de) | 1996-09-13 | 1997-09-11 | Substituierte benzocycloheptapyridine derivate verwendbar als farnesyl-protein transferase inhibitoren |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0931079B1 (de) |
| JP (1) | JP2001500508A (de) |
| KR (1) | KR20000036103A (de) |
| CN (1) | CN1122031C (de) |
| AT (1) | ATE209201T1 (de) |
| AU (1) | AU4337797A (de) |
| BR (1) | BR9711477A (de) |
| CA (1) | CA2264513C (de) |
| CZ (1) | CZ87499A3 (de) |
| DE (1) | DE69709774T2 (de) |
| ES (1) | ES2163195T3 (de) |
| HK (1) | HK1018443A1 (de) |
| HU (1) | HUP9904056A3 (de) |
| ID (1) | ID22156A (de) |
| IL (1) | IL128929A0 (de) |
| NO (1) | NO991229L (de) |
| NZ (1) | NZ334437A (de) |
| PL (1) | PL332253A1 (de) |
| SK (1) | SK33599A3 (de) |
| TR (1) | TR199901205T2 (de) |
| WO (1) | WO1998011099A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6358968B1 (en) | 1997-06-17 | 2002-03-19 | Schering Corporation | N-substituted urea inhibitors of farnesyl-protein transferase |
| IL133389A0 (en) * | 1997-06-17 | 2001-04-30 | Schering Corp | Novel n-substituted urea inhibitors of farnesyl-protein transferase |
| EP1049700B9 (de) | 1998-01-21 | 2006-05-10 | Millennium Pharmaceuticals, Inc. | Chemokin rezeptor antagonisten und verwndung |
| US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| JP2002501052A (ja) | 1998-01-21 | 2002-01-15 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | ケモカイン受容体アンタゴニストおよびその使用方法 |
| US6613905B1 (en) | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US6503926B2 (en) | 1998-09-04 | 2003-01-07 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6288083B1 (en) | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| NZ326035A (en) * | 1995-12-22 | 2000-01-28 | Schering Corp | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1997
- 1997-09-11 TR TR1999/01205T patent/TR199901205T2/xx unknown
- 1997-09-11 JP JP10513763A patent/JP2001500508A/ja not_active Ceased
- 1997-09-11 IL IL12892997A patent/IL128929A0/xx unknown
- 1997-09-11 KR KR1019997002125A patent/KR20000036103A/ko not_active Application Discontinuation
- 1997-09-11 ID IDW990087A patent/ID22156A/id unknown
- 1997-09-11 DE DE69709774T patent/DE69709774T2/de not_active Expired - Fee Related
- 1997-09-11 AU AU43377/97A patent/AU4337797A/en not_active Abandoned
- 1997-09-11 AT AT97941478T patent/ATE209201T1/de not_active IP Right Cessation
- 1997-09-11 CA CA002264513A patent/CA2264513C/en not_active Expired - Fee Related
- 1997-09-11 HU HU9904056A patent/HUP9904056A3/hu unknown
- 1997-09-11 EP EP97941478A patent/EP0931079B1/de not_active Expired - Lifetime
- 1997-09-11 NZ NZ334437A patent/NZ334437A/xx unknown
- 1997-09-11 SK SK335-99A patent/SK33599A3/sk unknown
- 1997-09-11 CN CN97199527A patent/CN1122031C/zh not_active Expired - Fee Related
- 1997-09-11 WO PCT/US1997/015905 patent/WO1998011099A1/en not_active Application Discontinuation
- 1997-09-11 ES ES97941478T patent/ES2163195T3/es not_active Expired - Lifetime
- 1997-09-11 BR BR9711477A patent/BR9711477A/pt unknown
- 1997-09-11 CZ CZ99874A patent/CZ87499A3/cs unknown
- 1997-09-11 PL PL97332253A patent/PL332253A1/xx unknown
-
1999
- 1999-03-12 NO NO991229A patent/NO991229L/no not_active Application Discontinuation
- 1999-08-07 HK HK99103415A patent/HK1018443A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0931079A1 (de) | 1999-07-28 |
| HUP9904056A2 (hu) | 2000-04-28 |
| DE69709774T2 (de) | 2002-08-08 |
| CA2264513A1 (en) | 1998-03-19 |
| HK1018443A1 (en) | 1999-12-24 |
| NO991229L (no) | 1999-05-12 |
| HUP9904056A3 (en) | 2001-10-29 |
| WO1998011099A1 (en) | 1998-03-19 |
| KR20000036103A (ko) | 2000-06-26 |
| AU4337797A (en) | 1998-04-02 |
| JP2001500508A (ja) | 2001-01-16 |
| CA2264513C (en) | 2004-03-30 |
| TR199901205T2 (xx) | 1999-07-21 |
| CN1236364A (zh) | 1999-11-24 |
| NO991229D0 (no) | 1999-03-12 |
| PL332253A1 (en) | 1999-08-30 |
| ES2163195T3 (es) | 2002-01-16 |
| IL128929A0 (en) | 2000-02-17 |
| ID22156A (id) | 1999-09-09 |
| ATE209201T1 (de) | 2001-12-15 |
| BR9711477A (pt) | 1999-08-24 |
| CZ87499A3 (cs) | 1999-08-11 |
| SK33599A3 (en) | 2000-03-13 |
| CN1122031C (zh) | 2003-09-24 |
| EP0931079B1 (de) | 2001-11-21 |
| NZ334437A (en) | 2000-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69732120D1 (de) | Trizyklische inhibitoren der farnesyl protein transferase | |
| DE69709774D1 (de) | Substituierte benzocycloheptapyridine derivate verwendbar als farnesyl-protein transferase inhibitoren | |
| NO991235L (no) | Forbindelser anvendelige for inhibering av farnesylproteintransferase | |
| DE69724130D1 (de) | Substituierte benzocycloheptapyridine derivate verwendbar als farnesyl protein transferase inhibitoren | |
| NO991231D0 (no) | Forbindelser for inhibering av farnesylproteintransferase |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |