ES2070517T3 - Productos intermedios en la preparacion del acido 4,5-difluoroantranilico. - Google Patents

Productos intermedios en la preparacion del acido 4,5-difluoroantranilico.

Info

Publication number
ES2070517T3
ES2070517T3 ES91918730T ES91918730T ES2070517T3 ES 2070517 T3 ES2070517 T3 ES 2070517T3 ES 91918730 T ES91918730 T ES 91918730T ES 91918730 T ES91918730 T ES 91918730T ES 2070517 T3 ES2070517 T3 ES 2070517T3
Authority
ES
Spain
Prior art keywords
preparation
acid
difluoroantranilico
intermediate products
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91918730T
Other languages
English (en)
Inventor
Tamim F Braish
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of ES2070517T3 publication Critical patent/ES2070517T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Sewage (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPUESTOS DE LA FORMULA (I), QUE SON INTERMEDIOS EN LA PREPARACION DE ACIDO 4,5-DIFLUOROANTRANILICO, UN INTERMEDIO POR SI MISMO EN LA SINTESIS DE ANTIBACTERIALES QUINOLONA Y METODOS DE PREPARACION DE ESTOS INTERMEDIOS.
ES91918730T 1990-10-31 1991-07-29 Productos intermedios en la preparacion del acido 4,5-difluoroantranilico. Expired - Lifetime ES2070517T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60666690A 1990-10-31 1990-10-31

Publications (1)

Publication Number Publication Date
ES2070517T3 true ES2070517T3 (es) 1995-06-01

Family

ID=24428951

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91918730T Expired - Lifetime ES2070517T3 (es) 1990-10-31 1991-07-29 Productos intermedios en la preparacion del acido 4,5-difluoroantranilico.

Country Status (13)

Country Link
US (1) US5436368A (es)
EP (1) EP0555283B1 (es)
JP (1) JP2552412B2 (es)
AT (1) ATE120729T1 (es)
CA (1) CA2091569C (es)
DE (1) DE69108737T2 (es)
DK (1) DK0555283T3 (es)
ES (1) ES2070517T3 (es)
FI (1) FI931938A0 (es)
GR (1) GR3015725T3 (es)
IE (1) IE65215B1 (es)
PT (1) PT99378B (es)
WO (1) WO1992007822A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113444021A (zh) * 2020-03-25 2021-09-28 深圳有为技术控股集团有限公司 邻胺基芳香酸的异羟肟酸重排法制备

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE136788C (es) *
DE130302C (es) *
CA1169078A (en) * 1980-12-29 1984-06-12 Michael J. Fifolt Method for the preparation of fluorophthalamic compounds
CA1181420A (en) * 1980-12-29 1985-01-22 Michael J. Fifolt Method for the preparation of fluoroanthranilic compounds
US4954639A (en) * 1989-08-28 1990-09-04 Occidental Chemical Corporation Single pot process for making a fluoroanthranilic acid

Also Published As

Publication number Publication date
PT99378B (pt) 1999-04-30
JP2552412B2 (ja) 1996-11-13
IE913783A1 (en) 1992-05-22
PT99378A (pt) 1992-09-30
DE69108737T2 (de) 1995-08-17
EP0555283B1 (en) 1995-04-05
GR3015725T3 (en) 1995-07-31
FI931938A (fi) 1993-04-29
DK0555283T3 (da) 1995-07-03
JPH05507287A (ja) 1993-10-21
FI931938A0 (fi) 1993-04-29
CA2091569C (en) 1997-02-18
WO1992007822A1 (en) 1992-05-14
DE69108737D1 (de) 1995-05-11
CA2091569A1 (en) 1992-05-01
ATE120729T1 (de) 1995-04-15
EP0555283A1 (en) 1993-08-18
IE65215B1 (en) 1995-10-04
US5436368A (en) 1995-07-25

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