AR241441A1 - Procedimiento para la obtencion de nuevos derivados del acido 4-benzoil-5hidroxi-benzociclobuten-1-carboxilico y sus sales. - Google Patents
Procedimiento para la obtencion de nuevos derivados del acido 4-benzoil-5hidroxi-benzociclobuten-1-carboxilico y sus sales.Info
- Publication number
- AR241441A1 AR241441A1 AR84296925A AR29692584A AR241441A1 AR 241441 A1 AR241441 A1 AR 241441A1 AR 84296925 A AR84296925 A AR 84296925A AR 29692584 A AR29692584 A AR 29692584A AR 241441 A1 AR241441 A1 AR 241441A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- hal
- alcohol
- substituted benzophenones
- solvolitically
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/39—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing halogen atoms bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/34—Monohydroxylic alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/38—Unsaturated compounds containing keto groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE NUEVOS DERIVADOS DEL ACIDO 4-BENZOIL-5- HIDROXI-BENZOCICLOBUTEN-1-CARBOXILICO DE LA FORMULA I, DONDE PH ES FENILO INSUSTITUIDO O MONOSUSTITUIDO POR ALQUILO, HALOGENO,ALQUILTIO, ALCOXI CARBONILO O CIANO, O BISUSTITUIDO POR HALOGENO Y R SIGNIFICA CARBOXI, ALCOXI -CARBONILO, CARBAMILO O CIANO. UN COMPUESTO DE LA FORMULA II, DONDE ALK ES ALQUILO, REACCIONA CON PH-C(=O)-HAL, DONDE HAL ES HALOGENO, Y EL PRODUCTO PRIMARIO SE DISOCIA SOLVOLITICAMENTE. SE TRATA CONVENIENTEMENTE PARA DAR LOS COMP. DE FORMULA (I). TIENE PROPIEDADES FARMACOLOGICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH327083 | 1983-06-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR241441A1 true AR241441A1 (es) | 1992-07-31 |
Family
ID=4252351
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR82307687A AR242947A1 (es) | 1983-06-15 | 1982-05-28 | Procedimiento para la obtencion de derivados de acidos 4-benzoil-5-hidroxi-benzoilciclobuten-1-carboxilico y sus sales. |
AR84296925A AR241441A1 (es) | 1983-06-15 | 1984-06-15 | Procedimiento para la obtencion de nuevos derivados del acido 4-benzoil-5hidroxi-benzociclobuten-1-carboxilico y sus sales. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR82307687A AR242947A1 (es) | 1983-06-15 | 1982-05-28 | Procedimiento para la obtencion de derivados de acidos 4-benzoil-5-hidroxi-benzoilciclobuten-1-carboxilico y sus sales. |
Country Status (22)
Country | Link |
---|---|
US (1) | US4523030A (es) |
EP (1) | EP0132566B1 (es) |
JP (1) | JPS6011440A (es) |
KR (1) | KR910004719B1 (es) |
AR (2) | AR242947A1 (es) |
AT (1) | ATE28068T1 (es) |
AU (1) | AU566626B2 (es) |
CY (1) | CY1515A (es) |
DD (1) | DD223704A5 (es) |
DE (1) | DE3464484D1 (es) |
DK (1) | DK291784A (es) |
ES (1) | ES8600197A1 (es) |
FI (1) | FI82681C (es) |
GR (1) | GR82168B (es) |
HK (1) | HK28490A (es) |
HU (1) | HU195760B (es) |
IE (1) | IE58279B1 (es) |
IL (1) | IL72079A (es) |
NO (1) | NO160436C (es) |
PH (1) | PH20431A (es) |
PT (1) | PT78723A (es) |
ZA (1) | ZA844494B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991001983A1 (en) * | 1989-07-28 | 1991-02-21 | The Dow Chemical Company | Cyclobutarene ketoanhydride and ketocarboxy monomeric and polymeric compositions |
DE59106417D1 (de) * | 1990-03-27 | 1995-10-12 | Ciba Geigy Ag | Neue benzocycloalkencarbonsäure und verfahren zu ihrer herstellung. |
FR2933975B1 (fr) * | 2008-07-17 | 2011-02-18 | Servier Lab | Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
WO2019221210A1 (ja) * | 2018-05-15 | 2019-11-21 | 旭化成株式会社 | カルバメートの製造方法及びイソシアネートの製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1195294A (en) * | 1967-08-21 | 1970-06-17 | Allen & Hanburys Ltd | Improvements in or relating to Pharmaceutical Compositions |
US3953500A (en) * | 1973-08-11 | 1976-04-27 | Takeda Chemical Industries, Ltd. | Benzalicyclic carboxylic acid derivative |
CH601166A5 (es) * | 1974-02-14 | 1978-06-30 | Ciba Geigy Ag |
-
1982
- 1982-05-28 AR AR82307687A patent/AR242947A1/es active
-
1984
- 1984-06-07 US US06/618,152 patent/US4523030A/en not_active Expired - Lifetime
- 1984-06-11 PH PH30799A patent/PH20431A/en unknown
- 1984-06-12 CY CY1515A patent/CY1515A/xx unknown
- 1984-06-12 IL IL72079A patent/IL72079A/xx not_active IP Right Cessation
- 1984-06-12 AT AT84106671T patent/ATE28068T1/de not_active IP Right Cessation
- 1984-06-12 DE DE8484106671T patent/DE3464484D1/de not_active Expired
- 1984-06-12 PT PT78723A patent/PT78723A/pt not_active IP Right Cessation
- 1984-06-12 EP EP84106671A patent/EP0132566B1/de not_active Expired
- 1984-06-13 FI FI842389A patent/FI82681C/fi not_active IP Right Cessation
- 1984-06-13 ES ES533380A patent/ES8600197A1/es not_active Expired
- 1984-06-13 GR GR75002A patent/GR82168B/el unknown
- 1984-06-14 HU HU842305A patent/HU195760B/hu not_active IP Right Cessation
- 1984-06-14 IE IE148784A patent/IE58279B1/en not_active IP Right Cessation
- 1984-06-14 DK DK291784A patent/DK291784A/da not_active Application Discontinuation
- 1984-06-14 ZA ZA844494A patent/ZA844494B/xx unknown
- 1984-06-14 NO NO842385A patent/NO160436C/no unknown
- 1984-06-14 KR KR1019840003349A patent/KR910004719B1/ko not_active IP Right Cessation
- 1984-06-14 DD DD84264151A patent/DD223704A5/de not_active IP Right Cessation
- 1984-06-14 AU AU29381/84A patent/AU566626B2/en not_active Ceased
- 1984-06-15 JP JP59122169A patent/JPS6011440A/ja active Granted
- 1984-06-15 AR AR84296925A patent/AR241441A1/es active
-
1990
- 1990-04-12 HK HK284/90A patent/HK28490A/xx not_active IP Right Cessation
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