ES8600197A1 - Procedimiento para la obtencion de nuevas benzofenonas sustituidas. - Google Patents

Procedimiento para la obtencion de nuevas benzofenonas sustituidas.

Info

Publication number
ES8600197A1
ES8600197A1 ES533380A ES533380A ES8600197A1 ES 8600197 A1 ES8600197 A1 ES 8600197A1 ES 533380 A ES533380 A ES 533380A ES 533380 A ES533380 A ES 533380A ES 8600197 A1 ES8600197 A1 ES 8600197A1
Authority
ES
Spain
Prior art keywords
group
formula
represents hydrogen
image
substituted benzophenones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533380A
Other languages
English (en)
Other versions
ES533380A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8600197A1 publication Critical patent/ES8600197A1/es
Publication of ES533380A0 publication Critical patent/ES533380A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/39—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing halogen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/34—Monohydroxylic alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/38—Unsaturated compounds containing keto groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE BENZOFENONAS SUSTITUIDAS, DE FORMULA GENERA (I), EN LA QUE PH SIGNIFICA FENILO Y R REPRESENTA CARBOXI LIBRE, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN SOMETER A UN TRATAMIENTO ACIDO UN COMPUESTO O UNA MEZCLA DE COMPUESTOS DE FORMULA GENERAL (II), EN LA QUE X1 Y X2 SIGNIFICAN JUNTOS UN GRUPO DE FORMULA: -C(FO)-O ENLAZADO A TRAVES DEL GRUPO CARBONILO CON EL RESTO PH; Y X3 SIGNIFICA HIDROGENO.DE APLICACION EN LA PREPARACION DE SUSTANCIAS ACTIVAS MEDICAMENTOSAS UTILIZADAS EN EL TRATAMIENTO DE ENFERMEDADES DOLOROSAS-INFLAMABLES, ESPECIALMENTE LAS COMPRENDIDAS EN EL CIRCULO DE FORMAS REUMATICAS, TALES COMO LA ARTRITIS CRONICA.
ES533380A 1983-06-15 1984-06-13 Procedimiento para la obtencion de nuevas benzofenonas sustituidas. Granted ES533380A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH327083 1983-06-15

Publications (2)

Publication Number Publication Date
ES8600197A1 true ES8600197A1 (es) 1985-10-01
ES533380A0 ES533380A0 (es) 1985-10-01

Family

ID=4252351

Family Applications (1)

Application Number Title Priority Date Filing Date
ES533380A Granted ES533380A0 (es) 1983-06-15 1984-06-13 Procedimiento para la obtencion de nuevas benzofenonas sustituidas.

Country Status (22)

Country Link
US (1) US4523030A (es)
EP (1) EP0132566B1 (es)
JP (1) JPS6011440A (es)
KR (1) KR910004719B1 (es)
AR (2) AR242947A1 (es)
AT (1) ATE28068T1 (es)
AU (1) AU566626B2 (es)
CY (1) CY1515A (es)
DD (1) DD223704A5 (es)
DE (1) DE3464484D1 (es)
DK (1) DK291784A (es)
ES (1) ES533380A0 (es)
FI (1) FI82681C (es)
GR (1) GR82168B (es)
HK (1) HK28490A (es)
HU (1) HU195760B (es)
IE (1) IE58279B1 (es)
IL (1) IL72079A (es)
NO (1) NO160436C (es)
PH (1) PH20431A (es)
PT (1) PT78723A (es)
ZA (1) ZA844494B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920702851A (ko) * 1989-07-26 1992-10-28 원본미기재 사이클로부타렌 케토안하이드라이드 및 케토카복시 단량체 및 중합체 조성물
AU643981B2 (en) * 1990-03-27 1993-12-02 Ciba Specialty Chemicals Holding Inc. New benzocycloalkene carboxylic acid and process for producing it
FR2933975B1 (fr) * 2008-07-17 2011-02-18 Servier Lab Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable.
WO2019221210A1 (ja) * 2018-05-15 2019-11-21 旭化成株式会社 カルバメートの製造方法及びイソシアネートの製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1195294A (en) * 1967-08-21 1970-06-17 Allen & Hanburys Ltd Improvements in or relating to Pharmaceutical Compositions
US3953500A (en) * 1973-08-11 1976-04-27 Takeda Chemical Industries, Ltd. Benzalicyclic carboxylic acid derivative
CH601166A5 (es) * 1974-02-14 1978-06-30 Ciba Geigy Ag

Also Published As

Publication number Publication date
PH20431A (en) 1987-01-05
GR82168B (es) 1984-12-13
FI842389A0 (fi) 1984-06-13
FI842389A (fi) 1984-12-16
EP0132566B1 (de) 1987-07-01
IE58279B1 (en) 1993-08-25
PT78723A (en) 1984-07-01
US4523030A (en) 1985-06-11
NO160436C (no) 1989-04-19
KR910004719B1 (ko) 1991-07-10
DK291784A (da) 1984-12-16
HU195760B (en) 1988-07-28
AU566626B2 (en) 1987-10-22
DK291784D0 (da) 1984-06-14
EP0132566A3 (en) 1985-04-17
HK28490A (en) 1990-04-20
DD223704A5 (de) 1985-06-19
CY1515A (en) 1990-08-03
FI82681C (fi) 1991-04-10
KR850001150A (ko) 1985-03-16
AR242947A1 (es) 1993-06-30
ATE28068T1 (de) 1987-07-15
ES533380A0 (es) 1985-10-01
IE841487L (en) 1984-12-15
FI82681B (fi) 1990-12-31
AU2938184A (en) 1984-12-20
JPS6011440A (ja) 1985-01-21
ZA844494B (en) 1985-02-27
NO160436B (no) 1989-01-09
IL72079A0 (en) 1984-10-31
HUT36772A (en) 1985-10-28
IL72079A (en) 1989-06-30
JPH0458457B2 (es) 1992-09-17
EP0132566A2 (de) 1985-02-13
DE3464484D1 (en) 1987-08-06
NO842385L (no) 1984-12-17
AR241441A1 (es) 1992-07-31

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20020506