IL72079A - 4-benzoyl-5-hydroxy-1-benzocyclobutenecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

4-benzoyl-5-hydroxy-1-benzocyclobutenecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL72079A
IL72079A IL72079A IL7207984A IL72079A IL 72079 A IL72079 A IL 72079A IL 72079 A IL72079 A IL 72079A IL 7207984 A IL7207984 A IL 7207984A IL 72079 A IL72079 A IL 72079A
Authority
IL
Israel
Prior art keywords
benzoyl
hydroxy
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL72079A
Other languages
English (en)
Other versions
IL72079A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL72079A0 publication Critical patent/IL72079A0/xx
Publication of IL72079A publication Critical patent/IL72079A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/39—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing halogen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/34—Monohydroxylic alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/38—Unsaturated compounds containing keto groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL72079A 1983-06-15 1984-06-12 4-benzoyl-5-hydroxy-1-benzocyclobutenecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL72079A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH327083 1983-06-15

Publications (2)

Publication Number Publication Date
IL72079A0 IL72079A0 (en) 1984-10-31
IL72079A true IL72079A (en) 1989-06-30

Family

ID=4252351

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72079A IL72079A (en) 1983-06-15 1984-06-12 4-benzoyl-5-hydroxy-1-benzocyclobutenecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US4523030A (xx)
EP (1) EP0132566B1 (xx)
JP (1) JPS6011440A (xx)
KR (1) KR910004719B1 (xx)
AR (2) AR242947A1 (xx)
AT (1) ATE28068T1 (xx)
AU (1) AU566626B2 (xx)
CY (1) CY1515A (xx)
DD (1) DD223704A5 (xx)
DE (1) DE3464484D1 (xx)
DK (1) DK291784A (xx)
ES (1) ES533380A0 (xx)
FI (1) FI82681C (xx)
GR (1) GR82168B (xx)
HK (1) HK28490A (xx)
HU (1) HU195760B (xx)
IE (1) IE58279B1 (xx)
IL (1) IL72079A (xx)
NO (1) NO160436C (xx)
PH (1) PH20431A (xx)
PT (1) PT78723A (xx)
ZA (1) ZA844494B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920702851A (ko) * 1989-07-26 1992-10-28 원본미기재 사이클로부타렌 케토안하이드라이드 및 케토카복시 단량체 및 중합체 조성물
AU643981B2 (en) * 1990-03-27 1993-12-02 Ciba Specialty Chemicals Holding Inc. New benzocycloalkene carboxylic acid and process for producing it
FR2933975B1 (fr) * 2008-07-17 2011-02-18 Servier Lab Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable.
WO2019221210A1 (ja) * 2018-05-15 2019-11-21 旭化成株式会社 カルバメートの製造方法及びイソシアネートの製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1195294A (en) * 1967-08-21 1970-06-17 Allen & Hanburys Ltd Improvements in or relating to Pharmaceutical Compositions
US3953500A (en) * 1973-08-11 1976-04-27 Takeda Chemical Industries, Ltd. Benzalicyclic carboxylic acid derivative
CH601166A5 (xx) * 1974-02-14 1978-06-30 Ciba Geigy Ag

Also Published As

Publication number Publication date
PH20431A (en) 1987-01-05
GR82168B (xx) 1984-12-13
FI842389A0 (fi) 1984-06-13
FI842389A (fi) 1984-12-16
EP0132566B1 (de) 1987-07-01
IE58279B1 (en) 1993-08-25
PT78723A (en) 1984-07-01
US4523030A (en) 1985-06-11
NO160436C (no) 1989-04-19
KR910004719B1 (ko) 1991-07-10
ES8600197A1 (es) 1985-10-01
DK291784A (da) 1984-12-16
HU195760B (en) 1988-07-28
AU566626B2 (en) 1987-10-22
DK291784D0 (da) 1984-06-14
EP0132566A3 (en) 1985-04-17
HK28490A (en) 1990-04-20
DD223704A5 (de) 1985-06-19
CY1515A (en) 1990-08-03
FI82681C (fi) 1991-04-10
KR850001150A (ko) 1985-03-16
AR242947A1 (es) 1993-06-30
ATE28068T1 (de) 1987-07-15
ES533380A0 (es) 1985-10-01
IE841487L (en) 1984-12-15
FI82681B (fi) 1990-12-31
AU2938184A (en) 1984-12-20
JPS6011440A (ja) 1985-01-21
ZA844494B (en) 1985-02-27
NO160436B (no) 1989-01-09
IL72079A0 (en) 1984-10-31
HUT36772A (en) 1985-10-28
JPH0458457B2 (xx) 1992-09-17
EP0132566A2 (de) 1985-02-13
DE3464484D1 (en) 1987-08-06
NO842385L (no) 1984-12-17
AR241441A1 (es) 1992-07-31

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Legal Events

Date Code Title Description
HP Change in proprietorship
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees