JPS5653678A - Preparation of 1,10-phenanthroilnes - Google Patents

Preparation of 1,10-phenanthroilnes

Info

Publication number
JPS5653678A
JPS5653678A JP8522280A JP8522280A JPS5653678A JP S5653678 A JPS5653678 A JP S5653678A JP 8522280 A JP8522280 A JP 8522280A JP 8522280 A JP8522280 A JP 8522280A JP S5653678 A JPS5653678 A JP S5653678A
Authority
JP
Japan
Prior art keywords
formula
group
phenanthroline
dihydro
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8522280A
Other languages
Japanese (ja)
Other versions
JPS5640156B2 (en
Inventor
Teruya Aka
Hiroshi Nagafusa
Chihiro Yokoo
Tadashi Kuribayashi
Sadao Machida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Priority to JP8522280A priority Critical patent/JPS5653678A/en
Publication of JPS5653678A publication Critical patent/JPS5653678A/en
Publication of JPS5640156B2 publication Critical patent/JPS5640156B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:1,4-Dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid of formula I (R is carboxylakyl).
EXAMPLE: 1, 4-Dihydro-1- carboxymethyl-4-oxo-1, 10-phenanthroline-3- carboxylic acid.
USE: Antibacterial agent having strong antibacterial activity to Gram-positive and Gram-negative bacteria.
PROCESS: The compound of formula I is prepared by reacting a compound of formula II with an alkylating agent of formula R'X (R' is a group which can be converted to R by hydrolysis; X is halogen) to introduce the R' group to the 1-position and at the same time, to hydrolyze the R' group to R group.
COPYRIGHT: (C)1981,JPO&Japio
JP8522280A 1980-06-25 1980-06-25 Preparation of 1,10-phenanthroilnes Granted JPS5653678A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8522280A JPS5653678A (en) 1980-06-25 1980-06-25 Preparation of 1,10-phenanthroilnes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8522280A JPS5653678A (en) 1980-06-25 1980-06-25 Preparation of 1,10-phenanthroilnes

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP7861472A Division JPS5622870B2 (en) 1972-08-05 1972-08-05

Publications (2)

Publication Number Publication Date
JPS5653678A true JPS5653678A (en) 1981-05-13
JPS5640156B2 JPS5640156B2 (en) 1981-09-18

Family

ID=13852533

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8522280A Granted JPS5653678A (en) 1980-06-25 1980-06-25 Preparation of 1,10-phenanthroilnes

Country Status (1)

Country Link
JP (1) JPS5653678A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999021860A1 (en) * 1997-10-24 1999-05-06 Fibrogen, Inc. Phenanthroline derivatives

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20120076A1 (en) 2012-01-24 2013-07-25 Pharmafilm Srl THREE-DIMENSIONAL SCAFFOLD CONSTITUTED BY FIBROIN AND POLYETHYLENE GLUTEN FOR CELL CULTURE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999021860A1 (en) * 1997-10-24 1999-05-06 Fibrogen, Inc. Phenanthroline derivatives

Also Published As

Publication number Publication date
JPS5640156B2 (en) 1981-09-18

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