JPS6434976A - Gamma-lactonecarboxylic acid derivative and production thereof - Google Patents

Gamma-lactonecarboxylic acid derivative and production thereof

Info

Publication number
JPS6434976A
JPS6434976A JP62270605A JP27060587A JPS6434976A JP S6434976 A JPS6434976 A JP S6434976A JP 62270605 A JP62270605 A JP 62270605A JP 27060587 A JP27060587 A JP 27060587A JP S6434976 A JPS6434976 A JP S6434976A
Authority
JP
Japan
Prior art keywords
group
formula
compound expressed
lactonecarboxylic
gamma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62270605A
Other languages
Japanese (ja)
Other versions
JPH0791283B2 (en
Inventor
Koichi Yoshioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP62270605A priority Critical patent/JPH0791283B2/en
Publication of JPS6434976A publication Critical patent/JPS6434976A/en
Publication of JPH0791283B2 publication Critical patent/JPH0791283B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound expressed by formula I (R<1> represents organic residue bonding through carbon atom; R<2> represents carboxyl group which may be esterified or amidated; X represents O or S which may be oxidized) or salt thereof. EXAMPLE:4-Nitrobenzyl 2-phenoxy-5-oxo-2-tetrahydrofurancarboxylate. USE:An antibacterial agent. PREPARATION:A compound expressed by formula II (R<2>' represents esterified carboxy group; Z<1> represents leaving group) is condensed with a compound expressed by the formula R<1>'-X'-Z<2> (R<1>' is same as R<1>; X' represents O or S; Z<2> represents leaving group) and, as necessary, the group R<1>' is converted into the other R<1>. S is treated with an oxidizing agent and converted into oxidized S or the esterified carboxy group is subjected to hydrolysis, amidation or salt- forming reaction.
JP62270605A 1986-10-29 1987-10-27 γ-Lactonecarboxylic acid derivative and method for producing the same Expired - Lifetime JPH0791283B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62270605A JPH0791283B2 (en) 1986-10-29 1987-10-27 γ-Lactonecarboxylic acid derivative and method for producing the same

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP25762986 1986-10-29
JP8447787 1987-04-06
JP62-84477 1987-04-06
JP61-257629 1987-04-06
JP62270605A JPH0791283B2 (en) 1986-10-29 1987-10-27 γ-Lactonecarboxylic acid derivative and method for producing the same

Publications (2)

Publication Number Publication Date
JPS6434976A true JPS6434976A (en) 1989-02-06
JPH0791283B2 JPH0791283B2 (en) 1995-10-04

Family

ID=27304557

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62270605A Expired - Lifetime JPH0791283B2 (en) 1986-10-29 1987-10-27 γ-Lactonecarboxylic acid derivative and method for producing the same

Country Status (1)

Country Link
JP (1) JPH0791283B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1950563A2 (en) 2002-09-11 2008-07-30 Michio Ishibashi Method for screening for a substance for promoting regeneration of macrophages
JP2015172015A (en) * 2014-03-11 2015-10-01 国立大学法人東北大学 Derivative of thiophene compound, thiophene compound and method of producing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1950563A2 (en) 2002-09-11 2008-07-30 Michio Ishibashi Method for screening for a substance for promoting regeneration of macrophages
JP2015172015A (en) * 2014-03-11 2015-10-01 国立大学法人東北大学 Derivative of thiophene compound, thiophene compound and method of producing them

Also Published As

Publication number Publication date
JPH0791283B2 (en) 1995-10-04

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