JPS5653685A - Production of cephalosporin derivative - Google Patents

Production of cephalosporin derivative

Info

Publication number
JPS5653685A
JPS5653685A JP12927479A JP12927479A JPS5653685A JP S5653685 A JPS5653685 A JP S5653685A JP 12927479 A JP12927479 A JP 12927479A JP 12927479 A JP12927479 A JP 12927479A JP S5653685 A JPS5653685 A JP S5653685A
Authority
JP
Japan
Prior art keywords
compound
formula
reaction
cephalosporin derivative
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12927479A
Other languages
Japanese (ja)
Other versions
JPS5930714B2 (en
Inventor
Masahiro Murakami
Masateru Kobayashi
Takanori Sone
Kazuyuki Shibuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP12927479A priority Critical patent/JPS5930714B2/en
Publication of JPS5653685A publication Critical patent/JPS5653685A/en
Publication of JPS5930714B2 publication Critical patent/JPS5930714B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Cephalosporin Compounds (AREA)

Abstract

PURPOSE: The reaction of a readily available 7-amino-cephem compound with 1H- tetrazolacetic acid or its reactive derivative gives a cephalosporin derivative useful as a synthetic intermediate of antibacterial.
CONSTITUTION: A compound of formula I or its salt is made to react with another compound of formula II or its reactive derivative in the carboxyl to give a cephalosporin derivative of formula III or its salt. The reaction is carried out in a solvent such as acetone, when necessary, in the presence of a condensing agent in a pH range from 6.0 to 7.5. The resultant compound of formula III is made to react with a compound of formula IV (R is H, methyl) to produce the compound of formula V useful as an antibacterial in high efficiency and safety. The compound of formula I is readily obtained by the reaction of 7-aminocephalospranic acid with 2-mercaptobenzimidazole.
COPYRIGHT: (C)1981,JPO&Japio
JP12927479A 1979-10-06 1979-10-06 Method for producing cephalosporin derivatives Expired JPS5930714B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12927479A JPS5930714B2 (en) 1979-10-06 1979-10-06 Method for producing cephalosporin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12927479A JPS5930714B2 (en) 1979-10-06 1979-10-06 Method for producing cephalosporin derivatives

Publications (2)

Publication Number Publication Date
JPS5653685A true JPS5653685A (en) 1981-05-13
JPS5930714B2 JPS5930714B2 (en) 1984-07-28

Family

ID=15005529

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12927479A Expired JPS5930714B2 (en) 1979-10-06 1979-10-06 Method for producing cephalosporin derivatives

Country Status (1)

Country Link
JP (1) JPS5930714B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60158909U (en) * 1984-03-31 1985-10-22 いすゞ自動車株式会社 Window frame molding structure

Also Published As

Publication number Publication date
JPS5930714B2 (en) 1984-07-28

Similar Documents

Publication Publication Date Title
JPS543087A (en) Preparation of cephalosporin compound
JPS5798270A (en) 1,2-disubstituted-4-chloroimidazole-5-acetic acid derivative
JPS54119494A (en) Preparation of cephalosporin compound
JPS5653685A (en) Production of cephalosporin derivative
JPS5448798A (en) 3-tetrazolyl-1-azaxanthone derivative and its preparation
JPS57159777A (en) 4-hydroxycyclopentenone compound and its preparation
JPS5289695A (en) Novel 7alpha-methoxycephalosporins and preparation thereof
JPS54138586A (en) Preparation of isocyanuric acid ester
JPS5716882A (en) Production of benzo-heteroring derivative
JPS53149912A (en) Preparation of alkoxyalkylidene compounds
JPS54154782A (en) Penicillin derivative and its salt
JPS5653688A (en) Novel cephalosporin derivative and its preparation
JPS57123140A (en) Ml-236b carboxylic acid amine salt and remedy for hyperlipemia containing said salt as active component
JPS5576887A (en) Imidazole dicarboxylic acid derivative
JPS51133296A (en) Processes for preparing 7-acylamino- 3-hydroxymethyl-2-cephem-4-carbox ylic acid derivatives
JPS54144392A (en) Cephalosporin derivative
JPS5419950A (en) Synthetic method of methylenebisbenzophenone derivative
JPS57145858A (en) Preparation of aziridine-2-carboxylic acid salt
JPS5754167A (en) Pyroglutamic acid derivative and its preparation
JPS5772988A (en) Production of novel cephalosporin derivaive
JPS55122788A (en) Preparation of cephalosporin compound
JPS5427594A (en) Penicillin derivative
JPS55147278A (en) Nicotinoylaminotriazine derivative
JPS5762238A (en) Preparation of crotonic acid
JPS57185293A (en) Cephamycin derivative and its preparation