JPS57185293A - Cephamycin derivative and its preparation - Google Patents

Cephamycin derivative and its preparation

Info

Publication number
JPS57185293A
JPS57185293A JP6893281A JP6893281A JPS57185293A JP S57185293 A JPS57185293 A JP S57185293A JP 6893281 A JP6893281 A JP 6893281A JP 6893281 A JP6893281 A JP 6893281A JP S57185293 A JPS57185293 A JP S57185293A
Authority
JP
Japan
Prior art keywords
compound shown
formula
formulai
compound
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6893281A
Other languages
Japanese (ja)
Other versions
JPH0136478B2 (en
Inventor
Junichi Nakazawa
Aoi Kunishima
Masahiko Yabuuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Sankyo Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd, Sankyo Co Ltd filed Critical Nippon Kayaku Co Ltd
Priority to JP6893281A priority Critical patent/JPS57185293A/en
Publication of JPS57185293A publication Critical patent/JPS57185293A/en
Publication of JPH0136478B2 publication Critical patent/JPH0136478B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound shown by the formulaI.
USE: An intermediate for preparing a compound having strong antibacterial power (e.g., 7-β-cyanomethylthioacetamido-7α-methoxy-3-(1-methyl-1H-tetrazole-5-yl)thiomethyl-3-cephem-4-carboxylic acid, etc.).
PROCESS: A cephamycin derivative shown by the formula II or its salt is reacted with a thiol compound shown by the formula III in the presence of an aqueous solvent or an aqueous organic solvent (e.g., acetone, ethyl acetate, etc.) including water under heating at 50W150°C, preferably 65W95°C, to give a compound shown by the formulaI. The amount of water as the aqueous solvent is a minimum limit amount to enable mechanical stirring, and ≤ five times, preferably 0.1W2 times as much as that for the compound shown by the formula II.
COPYRIGHT: (C)1982,JPO&Japio
JP6893281A 1981-05-08 1981-05-08 Cephamycin derivative and its preparation Granted JPS57185293A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6893281A JPS57185293A (en) 1981-05-08 1981-05-08 Cephamycin derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6893281A JPS57185293A (en) 1981-05-08 1981-05-08 Cephamycin derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS57185293A true JPS57185293A (en) 1982-11-15
JPH0136478B2 JPH0136478B2 (en) 1989-07-31

Family

ID=13387924

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6893281A Granted JPS57185293A (en) 1981-05-08 1981-05-08 Cephamycin derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57185293A (en)

Also Published As

Publication number Publication date
JPH0136478B2 (en) 1989-07-31

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