JPS57185293A - Cephamycin derivative and its preparation - Google Patents
Cephamycin derivative and its preparationInfo
- Publication number
- JPS57185293A JPS57185293A JP6893281A JP6893281A JPS57185293A JP S57185293 A JPS57185293 A JP S57185293A JP 6893281 A JP6893281 A JP 6893281A JP 6893281 A JP6893281 A JP 6893281A JP S57185293 A JPS57185293 A JP S57185293A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- formulai
- compound
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A compound shown by the formulaI.
USE: An intermediate for preparing a compound having strong antibacterial power (e.g., 7-β-cyanomethylthioacetamido-7α-methoxy-3-(1-methyl-1H-tetrazole-5-yl)thiomethyl-3-cephem-4-carboxylic acid, etc.).
PROCESS: A cephamycin derivative shown by the formula II or its salt is reacted with a thiol compound shown by the formula III in the presence of an aqueous solvent or an aqueous organic solvent (e.g., acetone, ethyl acetate, etc.) including water under heating at 50W150°C, preferably 65W95°C, to give a compound shown by the formulaI. The amount of water as the aqueous solvent is a minimum limit amount to enable mechanical stirring, and ≤ five times, preferably 0.1W2 times as much as that for the compound shown by the formula II.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6893281A JPS57185293A (en) | 1981-05-08 | 1981-05-08 | Cephamycin derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6893281A JPS57185293A (en) | 1981-05-08 | 1981-05-08 | Cephamycin derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57185293A true JPS57185293A (en) | 1982-11-15 |
JPH0136478B2 JPH0136478B2 (en) | 1989-07-31 |
Family
ID=13387924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6893281A Granted JPS57185293A (en) | 1981-05-08 | 1981-05-08 | Cephamycin derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57185293A (en) |
-
1981
- 1981-05-08 JP JP6893281A patent/JPS57185293A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPH0136478B2 (en) | 1989-07-31 |
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