JPS5484590A - 2-methyl-7-substituted-2 or 3-cephem-4-carboxylic acid, its salt, and their preparation - Google Patents

2-methyl-7-substituted-2 or 3-cephem-4-carboxylic acid, its salt, and their preparation

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Publication number
JPS5484590A
JPS5484590A JP15027677A JP15027677A JPS5484590A JP S5484590 A JPS5484590 A JP S5484590A JP 15027677 A JP15027677 A JP 15027677A JP 15027677 A JP15027677 A JP 15027677A JP S5484590 A JPS5484590 A JP S5484590A
Authority
JP
Japan
Prior art keywords
salt
compound
formula
group
cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15027677A
Other languages
Japanese (ja)
Inventor
Takashi Kamiya
Takao Takatani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority to JP15027677A priority Critical patent/JPS5484590A/en
Priority to US05/915,459 priority patent/US4299829A/en
Priority to IT2798278A priority patent/IT1109975B/en
Publication of JPS5484590A publication Critical patent/JPS5484590A/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I: (R1 is amino or formylamino group; R2 is 2W4C alkyl group) and is salt.
EXAMPLE: 2-Methyl-7-[2-ethoxyimino-2-(2-aminothiazole-4-yl)acetamido]-3-cephem- 4-carboxylic hydrochloride (syn-isomer).
USE: Antibacterials.
PROCESS: A compound of formula II, its reactive derivative at the amino group, or its salt is reacted with a compound of formula III, its reactive derivative at the carboxy group, or its salt to give the compound of formula I or its salt. The compound of formula I, wherein R1 is a formylamino group, or its salt can be converted to a compound of formula I, wherein R1 is an amino group by removing the formyl group with conc. hydrochoric acid.
COPYRIGHT: (C)1979,JPO&Japio
JP15027677A 1976-03-12 1977-12-13 2-methyl-7-substituted-2 or 3-cephem-4-carboxylic acid, its salt, and their preparation Pending JPS5484590A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP15027677A JPS5484590A (en) 1977-12-13 1977-12-13 2-methyl-7-substituted-2 or 3-cephem-4-carboxylic acid, its salt, and their preparation
US05/915,459 US4299829A (en) 1976-03-12 1978-06-14 2-Lower alkyl-7-substituted-2 or 3-cephem 4-carboxylic acid compounds
IT2798278A IT1109975B (en) 1977-09-26 1978-09-22 2-Alkyl-7-amino-thiazolyl-acetamido-cephem-4-carboxylic acid(s) - useful as broad spectrum antibacterials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15027677A JPS5484590A (en) 1977-12-13 1977-12-13 2-methyl-7-substituted-2 or 3-cephem-4-carboxylic acid, its salt, and their preparation

Publications (1)

Publication Number Publication Date
JPS5484590A true JPS5484590A (en) 1979-07-05

Family

ID=15493414

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15027677A Pending JPS5484590A (en) 1976-03-12 1977-12-13 2-methyl-7-substituted-2 or 3-cephem-4-carboxylic acid, its salt, and their preparation

Country Status (1)

Country Link
JP (1) JPS5484590A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5946287A (en) * 1982-07-23 1984-03-15 Meiji Seika Kaisha Ltd Novel 1-oxa-1-dethia-cephalosporin derivative
US10348041B2 (en) 2016-11-24 2019-07-09 Honda Motor Co., Ltd. Connector structure and electric vehicle

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5946287A (en) * 1982-07-23 1984-03-15 Meiji Seika Kaisha Ltd Novel 1-oxa-1-dethia-cephalosporin derivative
JPH0352472B2 (en) * 1982-07-23 1991-08-12 Meiji Seika Kk
US10348041B2 (en) 2016-11-24 2019-07-09 Honda Motor Co., Ltd. Connector structure and electric vehicle
US10608385B2 (en) 2016-11-24 2020-03-31 Honda Motor Co., Ltd. Connector structure and electric vehicle

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