IT1109975B - 2-Alkyl-7-amino-thiazolyl-acetamido-cephem-4-carboxylic acid(s) - useful as broad spectrum antibacterials - Google Patents

2-Alkyl-7-amino-thiazolyl-acetamido-cephem-4-carboxylic acid(s) - useful as broad spectrum antibacterials

Info

Publication number
IT1109975B
IT1109975B IT2798278A IT2798278A IT1109975B IT 1109975 B IT1109975 B IT 1109975B IT 2798278 A IT2798278 A IT 2798278A IT 2798278 A IT2798278 A IT 2798278A IT 1109975 B IT1109975 B IT 1109975B
Authority
IT
Italy
Prior art keywords
alkyl
cephem
acetamido
thiazolyl
amino
Prior art date
Application number
IT2798278A
Other languages
Italian (it)
Other versions
IT7827982A0 (en
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/836,909 external-priority patent/US4152433A/en
Priority claimed from JP15027677A external-priority patent/JPS5484590A/en
Priority claimed from US05/915,459 external-priority patent/US4299829A/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IT7827982A0 publication Critical patent/IT7827982A0/en
Application granted granted Critical
Publication of IT1109975B publication Critical patent/IT1109975B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

(A) 2-Alkyl-7-aminothiazolylacetamidocephem-4-carboxylic acids of formula (I) and their salts are new: (R1 is 1-6C alkyl; R2 is opt. protected COOH; R3 is opt. protected NH2, and R4 is 1-6C alkyl or haloalkyl or 2-6C unsatd. aliphatic gp.). (B) Thiazolylacetic acids of formula (II) and their salts are new: (R4a is 2-6C unsatd. aliphatic gp.). (I) are broad-spectrum antibacterials. (II) are intermediates in the prepn. of some cpds. (I).
IT2798278A 1977-09-26 1978-09-22 2-Alkyl-7-amino-thiazolyl-acetamido-cephem-4-carboxylic acid(s) - useful as broad spectrum antibacterials IT1109975B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US05/836,909 US4152433A (en) 1976-03-12 1977-09-26 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions
JP15027677A JPS5484590A (en) 1977-12-13 1977-12-13 2-methyl-7-substituted-2 or 3-cephem-4-carboxylic acid, its salt, and their preparation
US05/915,459 US4299829A (en) 1976-03-12 1978-06-14 2-Lower alkyl-7-substituted-2 or 3-cephem 4-carboxylic acid compounds
GB7833766 1978-08-17

Publications (2)

Publication Number Publication Date
IT7827982A0 IT7827982A0 (en) 1978-09-22
IT1109975B true IT1109975B (en) 1985-12-23

Family

ID=27449081

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2798278A IT1109975B (en) 1977-09-26 1978-09-22 2-Alkyl-7-amino-thiazolyl-acetamido-cephem-4-carboxylic acid(s) - useful as broad spectrum antibacterials

Country Status (1)

Country Link
IT (1) IT1109975B (en)

Also Published As

Publication number Publication date
IT7827982A0 (en) 1978-09-22

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