JPS57145858A - Preparation of aziridine-2-carboxylic acid salt - Google Patents
Preparation of aziridine-2-carboxylic acid saltInfo
- Publication number
- JPS57145858A JPS57145858A JP3125381A JP3125381A JPS57145858A JP S57145858 A JPS57145858 A JP S57145858A JP 3125381 A JP3125381 A JP 3125381A JP 3125381 A JP3125381 A JP 3125381A JP S57145858 A JPS57145858 A JP S57145858A
- Authority
- JP
- Japan
- Prior art keywords
- water
- acid salt
- organic solvent
- alkali metal
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
PURPOSE: To prepare the titled compound useful as an intermediate of pesticides and pharmaceuticals, in high concentration and high yield, by treating α-amino- β-halogenopropionitrile or its mineral acid salt with the hydroxide of an alkali metal, etc., in water or a water-containing organic solvent.
CONSTITUTION: The objective compound of formula II (M is alkali metal or alkaline earth metal; m and n are 1 or 2) can be prepared by treating the α- amino-β-halogenopropionitrile of formulaI(X is Cl or Br) or its mineral acid salt with an alkali metal or an alkaline earth metal hydroxide in water or in a water-containing organic solvent. The water-miscible organic solvent is, e.g. methanol. The reaction is preferably carried out at 0W100°C for 0.5W50hr.
EFFECT: The hydrolysis of the nitrile group and the intramolecular dehydrochlorination reaction (cyclization reaction) take place simultaneously, and the compound of formula II can be prepared selectively, in one step, without producing by-products.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3125381A JPS6039356B2 (en) | 1981-03-06 | 1981-03-06 | Production method of aziridine-2-carboxylate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3125381A JPS6039356B2 (en) | 1981-03-06 | 1981-03-06 | Production method of aziridine-2-carboxylate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57145858A true JPS57145858A (en) | 1982-09-09 |
JPS6039356B2 JPS6039356B2 (en) | 1985-09-05 |
Family
ID=12326188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3125381A Expired JPS6039356B2 (en) | 1981-03-06 | 1981-03-06 | Production method of aziridine-2-carboxylate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6039356B2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6439860U (en) * | 1987-09-04 | 1989-03-09 |
-
1981
- 1981-03-06 JP JP3125381A patent/JPS6039356B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6039356B2 (en) | 1985-09-05 |
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