JPS57145858A - Preparation of aziridine-2-carboxylic acid salt - Google Patents

Preparation of aziridine-2-carboxylic acid salt

Info

Publication number
JPS57145858A
JPS57145858A JP3125381A JP3125381A JPS57145858A JP S57145858 A JPS57145858 A JP S57145858A JP 3125381 A JP3125381 A JP 3125381A JP 3125381 A JP3125381 A JP 3125381A JP S57145858 A JPS57145858 A JP S57145858A
Authority
JP
Japan
Prior art keywords
water
acid salt
organic solvent
alkali metal
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3125381A
Other languages
Japanese (ja)
Other versions
JPS6039356B2 (en
Inventor
Ryuichi Mita
Toshio Kato
Chojiro Higuchi
Nobuyuki Kawashima
Masaharu Ooka
Teruhiro Yamaguchi
Shosuke Nagai
Takao Takano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP3125381A priority Critical patent/JPS6039356B2/en
Publication of JPS57145858A publication Critical patent/JPS57145858A/en
Publication of JPS6039356B2 publication Critical patent/JPS6039356B2/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

PURPOSE: To prepare the titled compound useful as an intermediate of pesticides and pharmaceuticals, in high concentration and high yield, by treating α-amino- β-halogenopropionitrile or its mineral acid salt with the hydroxide of an alkali metal, etc., in water or a water-containing organic solvent.
CONSTITUTION: The objective compound of formula II (M is alkali metal or alkaline earth metal; m and n are 1 or 2) can be prepared by treating the α- amino-β-halogenopropionitrile of formulaI(X is Cl or Br) or its mineral acid salt with an alkali metal or an alkaline earth metal hydroxide in water or in a water-containing organic solvent. The water-miscible organic solvent is, e.g. methanol. The reaction is preferably carried out at 0W100°C for 0.5W50hr.
EFFECT: The hydrolysis of the nitrile group and the intramolecular dehydrochlorination reaction (cyclization reaction) take place simultaneously, and the compound of formula II can be prepared selectively, in one step, without producing by-products.
COPYRIGHT: (C)1982,JPO&Japio
JP3125381A 1981-03-06 1981-03-06 Production method of aziridine-2-carboxylate Expired JPS6039356B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3125381A JPS6039356B2 (en) 1981-03-06 1981-03-06 Production method of aziridine-2-carboxylate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3125381A JPS6039356B2 (en) 1981-03-06 1981-03-06 Production method of aziridine-2-carboxylate

Publications (2)

Publication Number Publication Date
JPS57145858A true JPS57145858A (en) 1982-09-09
JPS6039356B2 JPS6039356B2 (en) 1985-09-05

Family

ID=12326188

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3125381A Expired JPS6039356B2 (en) 1981-03-06 1981-03-06 Production method of aziridine-2-carboxylate

Country Status (1)

Country Link
JP (1) JPS6039356B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6439860U (en) * 1987-09-04 1989-03-09

Also Published As

Publication number Publication date
JPS6039356B2 (en) 1985-09-05

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