JPS5748973A - Preparation of 2-hydroxyquinoxaline derivative - Google Patents
Preparation of 2-hydroxyquinoxaline derivativeInfo
- Publication number
- JPS5748973A JPS5748973A JP12480180A JP12480180A JPS5748973A JP S5748973 A JPS5748973 A JP S5748973A JP 12480180 A JP12480180 A JP 12480180A JP 12480180 A JP12480180 A JP 12480180A JP S5748973 A JPS5748973 A JP S5748973A
- Authority
- JP
- Japan
- Prior art keywords
- aqueous solution
- hydroxyquinoxaline
- iron
- tin
- zinc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To obtain advantageously the titled compound useful as an intermediate for synthesizing a drug or agricultural chemical, etc., by reducing 2-hydroxyquinoxaline-4-oxide derivative with zinc, iron, or tin in the presence of an alkali aqueous solution without adding an organic solvent.
CONSTITUTION: A 2-hydroxyqunoxaline-4-oxide derivative shown by the formula I (X is halogen, or trifluoromethyl) is reduced with zinc, iron, or tin (preferably iron) in the absence of an organic solvent in the presence of an alkali aqueous solution (preferably aqueous solution of sodium hydroxide or aqueous solution of potassium hydroxide) to give a 2-hydroxyquinoxaline shown by the formula II.
EFFECT: By-products are slightly prepared, metallic powder is economically used as a reducing agent, and water is advantageously used as a solvent. The reaction is carried out at relatively low temperature.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12480180A JPS5748973A (en) | 1980-09-09 | 1980-09-09 | Preparation of 2-hydroxyquinoxaline derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12480180A JPS5748973A (en) | 1980-09-09 | 1980-09-09 | Preparation of 2-hydroxyquinoxaline derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5748973A true JPS5748973A (en) | 1982-03-20 |
Family
ID=14894455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12480180A Pending JPS5748973A (en) | 1980-09-09 | 1980-09-09 | Preparation of 2-hydroxyquinoxaline derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5748973A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3419471A1 (en) * | 1983-05-25 | 1984-11-29 | Nippon Kayaku K.K., Tokio/Tokyo | METHOD FOR PRODUCING 2-CHINOXALINOLS |
-
1980
- 1980-09-09 JP JP12480180A patent/JPS5748973A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3419471A1 (en) * | 1983-05-25 | 1984-11-29 | Nippon Kayaku K.K., Tokio/Tokyo | METHOD FOR PRODUCING 2-CHINOXALINOLS |
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