JPS57188575A - Preparation of 2-hydroxyquinoxaline derivative - Google Patents

Preparation of 2-hydroxyquinoxaline derivative

Info

Publication number
JPS57188575A
JPS57188575A JP7116381A JP7116381A JPS57188575A JP S57188575 A JPS57188575 A JP S57188575A JP 7116381 A JP7116381 A JP 7116381A JP 7116381 A JP7116381 A JP 7116381A JP S57188575 A JPS57188575 A JP S57188575A
Authority
JP
Japan
Prior art keywords
nabh
aqueous solution
alkaline aqueous
organic solvent
compound expressed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7116381A
Other languages
Japanese (ja)
Inventor
Koichi Ura
Itsutsune Sakata
Kenji Makino
Kazuya Kusano
Katsuyuki Morimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Priority to JP7116381A priority Critical patent/JPS57188575A/en
Publication of JPS57188575A publication Critical patent/JPS57188575A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled substance useful as an intermediate for medicines and agricultural chemicals, by reducing a 2-hydroxyquinoxaline-4-oxide derivative with NaBH4 in the presence of an alkaline aqueous solution in the absence of an organic solvent at a low temperature.
CONSTITUTION: A compound expressed by formulaI(X is halogen or CF3) is reduced with NaBH4 in the presence of an alkaline aqueous solution in the absence of an organic solvent at 10W30°C to give a compound expressed by formula II. NaOH in a concentration of 5W10wt% is preferred as the alkaline aqueous solution, and 0.5W1.0mol, based on one mole compound expressed by formulaI, NaBH4 to be added is enough for the reaction.
EFFECT: By-products are scarcely formed by the reduction in the presence of the alkaline aqueous solution, and the reducing reagent NaBH4 is stabilized to advance the reaction smoothly due to the uniform solution of the raw material compound. The use of water in place of the organic solvent is economical.
COPYRIGHT: (C)1982,JPO&Japio
JP7116381A 1981-05-12 1981-05-12 Preparation of 2-hydroxyquinoxaline derivative Pending JPS57188575A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7116381A JPS57188575A (en) 1981-05-12 1981-05-12 Preparation of 2-hydroxyquinoxaline derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7116381A JPS57188575A (en) 1981-05-12 1981-05-12 Preparation of 2-hydroxyquinoxaline derivative

Publications (1)

Publication Number Publication Date
JPS57188575A true JPS57188575A (en) 1982-11-19

Family

ID=13452689

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7116381A Pending JPS57188575A (en) 1981-05-12 1981-05-12 Preparation of 2-hydroxyquinoxaline derivative

Country Status (1)

Country Link
JP (1) JPS57188575A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3419471A1 (en) * 1983-05-25 1984-11-29 Nippon Kayaku K.K., Tokio/Tokyo METHOD FOR PRODUCING 2-CHINOXALINOLS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3419471A1 (en) * 1983-05-25 1984-11-29 Nippon Kayaku K.K., Tokio/Tokyo METHOD FOR PRODUCING 2-CHINOXALINOLS

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