JPS5690055A - Novel preparation of aziridine-2-carboxylic acid salt - Google Patents
Novel preparation of aziridine-2-carboxylic acid saltInfo
- Publication number
- JPS5690055A JPS5690055A JP16768179A JP16768179A JPS5690055A JP S5690055 A JPS5690055 A JP S5690055A JP 16768179 A JP16768179 A JP 16768179A JP 16768179 A JP16768179 A JP 16768179A JP S5690055 A JPS5690055 A JP S5690055A
- Authority
- JP
- Japan
- Prior art keywords
- aziridine
- alkali
- carboxylic acid
- earth
- acid salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the titled compound which is an intermediate for an agricultural chemical, a medicine, etc. readily in high yield, by reacting an easily preparable and inexpensive α-halogenoacrylonitrile as a raw material with ammonia, and then with an alkali earth metal hydroxide.
CONSTITUTION: An α-halogenoacrylonitrile as a raw material is reacted with ammonia in water or an organic solvent to give an α-halogeno-β-aminopropionitrile, which is, without isolation from the reaction system, treated with an alkali (earth) metal hydroxide in the presence of water subsequently to afford an alkali (earth) metallic salt of aziridine-2-carboxylic acid. The reaction proceeds in a greatly simplified process under mild conditions, and the reaction operation is simple.
USE: An intermediate for an α-amino acid, e.g. serine.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54167681A JPS6039354B2 (en) | 1979-12-25 | 1979-12-25 | New method for producing aziridine-2-carboxylate |
EP19800304439 EP0030474B1 (en) | 1979-12-10 | 1980-12-09 | Process for the production of dl-serines |
US06/214,728 US4393000A (en) | 1979-12-12 | 1980-12-09 | Cyclization process for producing aziridine-2-carboxylic acid or its salts |
EP80304440A EP0030475B1 (en) | 1979-12-10 | 1980-12-09 | Process for producing solutions of aziridine-2-carboxylic acid salts |
DE8080304440T DE3067054D1 (en) | 1979-12-10 | 1980-12-09 | Process for producing solutions of aziridine-2-carboxylic acid salts |
DE8080304439T DE3061695D1 (en) | 1979-12-10 | 1980-12-09 | Process for the production of dl-serines |
AU65259/80A AU536508B2 (en) | 1979-12-12 | 1980-12-10 | Aziridine-2-carboxylic acid |
MX10155580U MX6502E (en) | 1979-12-12 | 1980-12-11 | PROCEDURE FOR PREPARING AZIRIDIN-2-CARBOXYL ACID SALT |
CA000366597A CA1161854A (en) | 1979-12-12 | 1980-12-11 | Process for producing aziridine-2-carboxylic acid or its salts |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54167681A JPS6039354B2 (en) | 1979-12-25 | 1979-12-25 | New method for producing aziridine-2-carboxylate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5690055A true JPS5690055A (en) | 1981-07-21 |
JPS6039354B2 JPS6039354B2 (en) | 1985-09-05 |
Family
ID=15854244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54167681A Expired JPS6039354B2 (en) | 1979-12-10 | 1979-12-25 | New method for producing aziridine-2-carboxylate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6039354B2 (en) |
-
1979
- 1979-12-25 JP JP54167681A patent/JPS6039354B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6039354B2 (en) | 1985-09-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS57183756A (en) | Preparation of 4-hydroxy-2-pyrrolidone | |
JPS5690055A (en) | Novel preparation of aziridine-2-carboxylic acid salt | |
GB1259747A (en) | Process for the preparation of aliphatic tertiary amides | |
JPS57192392A (en) | Production of 3-alkoxymethylcephalosporin | |
US4070394A (en) | Carnitine nitrile halide preparation | |
JPS5459228A (en) | Preparation of ethylenediamine diacetonitrile | |
JPS577438A (en) | Production of acid chloride | |
JPS56100759A (en) | Preparation of aziridine-2-carboxylic acid | |
JPS5791982A (en) | Preparation of 5-methylfurfural | |
JPS55129257A (en) | Purification of acetonitrile containing hydrogen cyanide | |
JPS56158792A (en) | Preparation of amineborane | |
JPS57120570A (en) | Preparation of 1,3-dialkyl-2-imidazolidinone | |
JPS5622753A (en) | Preparation of alpha-halogeno-beta-alanine or its salt of mineral acid | |
JPS57146751A (en) | Preparation of aziridine-2-carboxylate | |
JPS5695158A (en) | Preparation of n-carbamoyl-p-hydroxyphenylglycine | |
JPS57145858A (en) | Preparation of aziridine-2-carboxylic acid salt | |
JPS5687556A (en) | Preparation of aziridine-2-carboxylate | |
JPS5626850A (en) | Preparation of 2-aminoacetal | |
JPS57146790A (en) | Novel synthesis of organopolysilane | |
SU493466A1 (en) | Method for producing methacrylamide | |
JPS5683470A (en) | Preparation of aziridine-2-carboxylic acid salt | |
JPS56100754A (en) | Preparation of 2-halogenoacrylonitrile | |
JPS57149253A (en) | Preparation of nitroacetic esters | |
JPS56161354A (en) | Improved preparation of dinitrodiphenyl ether | |
JPS55133357A (en) | Preparation of 1-cyano-2-hydroxy-3-phthalimidopropane |