JPS5622753A - Preparation of alpha-halogeno-beta-alanine or its salt of mineral acid - Google Patents
Preparation of alpha-halogeno-beta-alanine or its salt of mineral acidInfo
- Publication number
- JPS5622753A JPS5622753A JP9863479A JP9863479A JPS5622753A JP S5622753 A JPS5622753 A JP S5622753A JP 9863479 A JP9863479 A JP 9863479A JP 9863479 A JP9863479 A JP 9863479A JP S5622753 A JPS5622753 A JP S5622753A
- Authority
- JP
- Japan
- Prior art keywords
- mineral acid
- halogeno
- alanine
- salt
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To obtain the titled compound in short process in high yield useful as an intermediate for an α-amino acid, a drug, etc., by hydrolyzing a reaction product of an α,β-dihalogenopropionitrile and NH3 in a mineral acid without isolating the product.
CONSTITUTION: An α,β-dihalogenopropionitrile is reacted with NH3 in a solvent, e.g., water, methanol, ethanol, etc. at -40W30°C, preferably at -20W20°C, to give an α-halogeno-β-aminopropionitrile, which is not isolated from the reaction system and hydrolyzed continuously in a mineral acid at 50W150°C, preferably at 80W120°C, to prepare an α-halogeno-β-alanine or its salt of mineral acid.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9863479A JPS5622753A (en) | 1979-08-03 | 1979-08-03 | Preparation of alpha-halogeno-beta-alanine or its salt of mineral acid |
EP19800301165 EP0018177B1 (en) | 1979-04-12 | 1980-04-11 | Process for producing alpha-halogeno-beta-alanines or the mineral acid salts thereof |
DE8080301165T DE3060243D1 (en) | 1979-04-12 | 1980-04-11 | Process for producing alpha-halogeno-beta-alanines or the mineral acid salts thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9863479A JPS5622753A (en) | 1979-08-03 | 1979-08-03 | Preparation of alpha-halogeno-beta-alanine or its salt of mineral acid |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5622753A true JPS5622753A (en) | 1981-03-03 |
JPS6320811B2 JPS6320811B2 (en) | 1988-04-30 |
Family
ID=14224929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9863479A Granted JPS5622753A (en) | 1979-04-12 | 1979-08-03 | Preparation of alpha-halogeno-beta-alanine or its salt of mineral acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5622753A (en) |
-
1979
- 1979-08-03 JP JP9863479A patent/JPS5622753A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6320811B2 (en) | 1988-04-30 |
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