JPS5687541A - Preparation of amino acid ester - Google Patents

Preparation of amino acid ester

Info

Publication number
JPS5687541A
JPS5687541A JP16360379A JP16360379A JPS5687541A JP S5687541 A JPS5687541 A JP S5687541A JP 16360379 A JP16360379 A JP 16360379A JP 16360379 A JP16360379 A JP 16360379A JP S5687541 A JPS5687541 A JP S5687541A
Authority
JP
Japan
Prior art keywords
compound
halo
formula
preparation
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16360379A
Other languages
Japanese (ja)
Other versions
JPS642098B2 (en
Inventor
Kiyoshi Fukui
Junichiro Kita
Hiroshi Jibiki
Noboru Kakeya
Susumu Fujimura
Kiyomi Okimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ube Corp
Original Assignee
Ube Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries Ltd filed Critical Ube Industries Ltd
Priority to JP16360379A priority Critical patent/JPS5687541A/en
Publication of JPS5687541A publication Critical patent/JPS5687541A/en
Publication of JPS642098B2 publication Critical patent/JPS642098B2/ja
Granted legal-status Critical Current

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  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: To obtain the titled compound useful as an intermediate of pharmaceuticals and agricultural chemicals in high yield, by the reaction of a cyanoformate and an active methylene compound in the presence of the reaction product of stannous chloride and an N-halo compound, followed by treatment with water, etc.
CONSTITUTION: A compound of formula I (R is 1W4C alkyl) and an active methylene compound of formula II [R1 is CN, COR3 (R3 is 1W4C alkyl or 6W14C aryl), etc.; R2 is H, CN, COR3, etc.] are made to react in the presence of the reaction product of stannous chloride and an N-halo compound selected from the group of N-halobenzenesulfonamide, N-halo-ε-caprolactam and N-halosuccinimide. The product obtained is treated with water or an acidic aqueous solution (e.g. hydrochloric acid, sulfuric acid, etc.) at 0W35°C to give a compound of formula III (e.g. 1-amino-2-cyano-1,2-dimethoxycarbonylethylene).
COPYRIGHT: (C)1981,JPO&Japio
JP16360379A 1979-12-18 1979-12-18 Preparation of amino acid ester Granted JPS5687541A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16360379A JPS5687541A (en) 1979-12-18 1979-12-18 Preparation of amino acid ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16360379A JPS5687541A (en) 1979-12-18 1979-12-18 Preparation of amino acid ester

Publications (2)

Publication Number Publication Date
JPS5687541A true JPS5687541A (en) 1981-07-16
JPS642098B2 JPS642098B2 (en) 1989-01-13

Family

ID=15777057

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16360379A Granted JPS5687541A (en) 1979-12-18 1979-12-18 Preparation of amino acid ester

Country Status (1)

Country Link
JP (1) JPS5687541A (en)

Also Published As

Publication number Publication date
JPS642098B2 (en) 1989-01-13

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