JPS5687541A - Preparation of amino acid ester - Google Patents
Preparation of amino acid esterInfo
- Publication number
- JPS5687541A JPS5687541A JP16360379A JP16360379A JPS5687541A JP S5687541 A JPS5687541 A JP S5687541A JP 16360379 A JP16360379 A JP 16360379A JP 16360379 A JP16360379 A JP 16360379A JP S5687541 A JPS5687541 A JP S5687541A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- halo
- formula
- preparation
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PURPOSE: To obtain the titled compound useful as an intermediate of pharmaceuticals and agricultural chemicals in high yield, by the reaction of a cyanoformate and an active methylene compound in the presence of the reaction product of stannous chloride and an N-halo compound, followed by treatment with water, etc.
CONSTITUTION: A compound of formula I (R is 1W4C alkyl) and an active methylene compound of formula II [R1 is CN, COR3 (R3 is 1W4C alkyl or 6W14C aryl), etc.; R2 is H, CN, COR3, etc.] are made to react in the presence of the reaction product of stannous chloride and an N-halo compound selected from the group of N-halobenzenesulfonamide, N-halo-ε-caprolactam and N-halosuccinimide. The product obtained is treated with water or an acidic aqueous solution (e.g. hydrochloric acid, sulfuric acid, etc.) at 0W35°C to give a compound of formula III (e.g. 1-amino-2-cyano-1,2-dimethoxycarbonylethylene).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16360379A JPS5687541A (en) | 1979-12-18 | 1979-12-18 | Preparation of amino acid ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16360379A JPS5687541A (en) | 1979-12-18 | 1979-12-18 | Preparation of amino acid ester |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5687541A true JPS5687541A (en) | 1981-07-16 |
JPS642098B2 JPS642098B2 (en) | 1989-01-13 |
Family
ID=15777057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16360379A Granted JPS5687541A (en) | 1979-12-18 | 1979-12-18 | Preparation of amino acid ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5687541A (en) |
-
1979
- 1979-12-18 JP JP16360379A patent/JPS5687541A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS642098B2 (en) | 1989-01-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5690031A (en) | Preparation of aromatic aldehyde | |
Yonehara et al. | Chemical Studies on Blasticidin S I. Hydrolysis of Blasticidin S | |
JPS56125347A (en) | Preparation of dipeptide | |
JPS5687541A (en) | Preparation of amino acid ester | |
JPS55139375A (en) | Production of hydroxyflavan | |
JPS57108072A (en) | Preparation of n-acylcarnosine | |
JPS5687542A (en) | Preparation of amino acid ester | |
JPS5791982A (en) | Preparation of 5-methylfurfural | |
JPS5671049A (en) | Preparation of amino acid ester | |
JPS5781449A (en) | Cyclopropanecarboxamide derivative, its preparation and herbicide containinig said derivative as active component | |
JPS5536454A (en) | Novel immunosuppressive agent | |
JPS5622753A (en) | Preparation of alpha-halogeno-beta-alanine or its salt of mineral acid | |
JPS51115402A (en) | Process for preparation of alpha-amino acid | |
JPS5721400A (en) | Novel fortimicin derivative | |
JPS5671050A (en) | Preparation of amino acid ester | |
JPS5545608A (en) | Preparation of organosilver compound | |
JPS54115376A (en) | Preparation of 5-(4-hydroxyphenyl)-hydantoin | |
JPS5651478A (en) | 3-carbamoyl-pyrazolo 1,5-a pyridine and its preparation | |
JPS57140738A (en) | Cyclohexadiene derivative and its preparation | |
JPS57145858A (en) | Preparation of aziridine-2-carboxylic acid salt | |
JPS5629547A (en) | Preparation of 1-aryloxy-3-isopropylamino-2-propanol | |
JPS57122051A (en) | Preparation of(1,1'-bicyclohexyl)-1-carboxylic acid 2-(diethylamino)ethyl ester | |
JPS5772983A (en) | Preparation of 1,2,3,4,6,7,8,9-octahydrophenazine | |
JPS5553299A (en) | N2-substituted-phenyl-2,6-diaminonebularine | |
JPS5695158A (en) | Preparation of n-carbamoyl-p-hydroxyphenylglycine |