JPS5545608A - Preparation of organosilver compound - Google Patents
Preparation of organosilver compoundInfo
- Publication number
- JPS5545608A JPS5545608A JP11796578A JP11796578A JPS5545608A JP S5545608 A JPS5545608 A JP S5545608A JP 11796578 A JP11796578 A JP 11796578A JP 11796578 A JP11796578 A JP 11796578A JP S5545608 A JPS5545608 A JP S5545608A
- Authority
- JP
- Japan
- Prior art keywords
- methyl cellosolve
- compound
- formula
- solution
- silver nitrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: To obtain the title compound quantitatively, useful as chemotherapeutic agents of malignant tumor, insoluble in water and general organic solvents, by reacting a solution of a naphthoic acid amide derivative in methyl cellosolve with a solution of silver nitrate in methyl cellosolve.
CONSTITUTION: The compound of formula I (R is H or -CO-CH-Cl2; R1 is formula I or III; R2 is the same as H or R1) dissolved in ethylene glycol monomethyl ether (methyl cellosolve) is reacted with a solution of silver nitrate in methyl cellosolve at once to obtain an organosilver compound like the brown, amorphous, tasteless and odorless compound of formula IV, which has anticancer effects and good acceptability to man without side effects, and is given per os.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11796578A JPS5545608A (en) | 1978-09-27 | 1978-09-27 | Preparation of organosilver compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11796578A JPS5545608A (en) | 1978-09-27 | 1978-09-27 | Preparation of organosilver compound |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5545608A true JPS5545608A (en) | 1980-03-31 |
Family
ID=14724638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11796578A Pending JPS5545608A (en) | 1978-09-27 | 1978-09-27 | Preparation of organosilver compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5545608A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4863910A (en) * | 1986-05-20 | 1989-09-05 | Takeo Takayanagi | Complexes of AZO compounds and/or their salts and an antitumor agent and a method for reducing the growth of tumors |
US4956457A (en) * | 1986-05-20 | 1990-09-11 | Takeo Takayanagi | Disazo disulfonamides compounds |
-
1978
- 1978-09-27 JP JP11796578A patent/JPS5545608A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4863910A (en) * | 1986-05-20 | 1989-09-05 | Takeo Takayanagi | Complexes of AZO compounds and/or their salts and an antitumor agent and a method for reducing the growth of tumors |
US4956457A (en) * | 1986-05-20 | 1990-09-11 | Takeo Takayanagi | Disazo disulfonamides compounds |
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