JPS5671049A - Preparation of amino acid ester - Google Patents

Preparation of amino acid ester

Info

Publication number
JPS5671049A
JPS5671049A JP14777779A JP14777779A JPS5671049A JP S5671049 A JPS5671049 A JP S5671049A JP 14777779 A JP14777779 A JP 14777779A JP 14777779 A JP14777779 A JP 14777779A JP S5671049 A JPS5671049 A JP S5671049A
Authority
JP
Japan
Prior art keywords
cyanoformate
formula
compound
bromocyanoacetate
titanium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14777779A
Other languages
Japanese (ja)
Other versions
JPS641462B2 (en
Inventor
Kiyoshi Fukui
Noboru Kakeya
Susumu Fujimura
Junichiro Kita
Kiyomi Okimoto
Hiroshi Sugihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ube Corp
Original Assignee
Ube Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries Ltd filed Critical Ube Industries Ltd
Priority to JP14777779A priority Critical patent/JPS5671049A/en
Publication of JPS5671049A publication Critical patent/JPS5671049A/en
Publication of JPS641462B2 publication Critical patent/JPS641462B2/ja
Granted legal-status Critical Current

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  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: To obtain the titled compound useful as an intermediate for an additive of a medicine, agricultural chemical and high polymer in high yield, by reacting a cyanoformate with an active bromomethylene compound in the presence of a low-valent metal halide, and treating the reaction product with water, etc.
CONSTITUTION: A cyanoformate of formula I (R1 is 1W4C alkyl), e.g. methyl cyanoformate or butyl cyanoformate, is reacted with an active methylene compound, e.g. methyl bromocyanoacetate or propyl bromocyanoacetate, of formula II (R2 is 1W4C alkyl; Y is group of CN, etc.) in the presence of a metal halide of the formula MXn (M is tinhe or titanium; X is Cl or Br; n is 2 when M is tin, and 3 when M is titanium), and the reaction product is then treated with water or an acidic aqueous solution to give the titled compound of formula III without using a base.
COPYRIGHT: (C)1981,JPO&Japio
JP14777779A 1979-11-16 1979-11-16 Preparation of amino acid ester Granted JPS5671049A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14777779A JPS5671049A (en) 1979-11-16 1979-11-16 Preparation of amino acid ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14777779A JPS5671049A (en) 1979-11-16 1979-11-16 Preparation of amino acid ester

Publications (2)

Publication Number Publication Date
JPS5671049A true JPS5671049A (en) 1981-06-13
JPS641462B2 JPS641462B2 (en) 1989-01-11

Family

ID=15437941

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14777779A Granted JPS5671049A (en) 1979-11-16 1979-11-16 Preparation of amino acid ester

Country Status (1)

Country Link
JP (1) JPS5671049A (en)

Also Published As

Publication number Publication date
JPS641462B2 (en) 1989-01-11

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