JPS5671050A - Preparation of amino acid ester - Google Patents

Preparation of amino acid ester

Info

Publication number
JPS5671050A
JPS5671050A JP14777879A JP14777879A JPS5671050A JP S5671050 A JPS5671050 A JP S5671050A JP 14777879 A JP14777879 A JP 14777879A JP 14777879 A JP14777879 A JP 14777879A JP S5671050 A JPS5671050 A JP S5671050A
Authority
JP
Japan
Prior art keywords
cyanoformate
formula
alkyl
metal halide
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14777879A
Other languages
Japanese (ja)
Other versions
JPS641463B2 (en
Inventor
Kiyoshi Fukui
Kiyomi Okimoto
Junichiro Kita
Hiroshi Sugihara
Susumu Fujimura
Noboru Kakeya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ube Corp
Original Assignee
Ube Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries Ltd filed Critical Ube Industries Ltd
Priority to JP14777879A priority Critical patent/JPS5671050A/en
Publication of JPS5671050A publication Critical patent/JPS5671050A/en
Publication of JPS641463B2 publication Critical patent/JPS641463B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: To obtain the titled compound which is a synthetic intermediate for additives of medicines, agricultural chemicals and high polymers readily in high yield, by reacting a cyanoformate with an active methylene compound in the presence of a metal halide.
CONSTITUTION: A cyanoformate of formula I (R1 is 1W4C alkyl), e.g. methyl cyanoformate of butyl cyanoformate, is reacted with an active methylene compound of formula II (R2 is 1W4C alkyl: Y is group of CN, etc.), e.g. methyl cyanoacetate or propyl cyanoacetate, in the presence of a metal halide of the formula MXn (M is titanium or tin; X is F, Cl, Br or I; n is the same number as the miximum valence of M), e.g. titanium tetrachloride or stannic chloride, and the resultant reaction product is then treated with water or an acidic aqueous solution to give the titled compound of formula III in high yield without using a base.
COPYRIGHT: (C)1981,JPO&Japio
JP14777879A 1979-11-16 1979-11-16 Preparation of amino acid ester Granted JPS5671050A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14777879A JPS5671050A (en) 1979-11-16 1979-11-16 Preparation of amino acid ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14777879A JPS5671050A (en) 1979-11-16 1979-11-16 Preparation of amino acid ester

Publications (2)

Publication Number Publication Date
JPS5671050A true JPS5671050A (en) 1981-06-13
JPS641463B2 JPS641463B2 (en) 1989-01-11

Family

ID=15437965

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14777879A Granted JPS5671050A (en) 1979-11-16 1979-11-16 Preparation of amino acid ester

Country Status (1)

Country Link
JP (1) JPS5671050A (en)

Also Published As

Publication number Publication date
JPS641463B2 (en) 1989-01-11

Similar Documents

Publication Publication Date Title
JPS54148788A (en) 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation
JPS5690031A (en) Preparation of aromatic aldehyde
JPS57109787A (en) Pyrazoloindazole derivative
JPS5671050A (en) Preparation of amino acid ester
JPS5655359A (en) Halogenated alpha-amino acid, and its preparation
JPS57192392A (en) Production of 3-alkoxymethylcephalosporin
JPS5671049A (en) Preparation of amino acid ester
JPS574987A (en) Pyridoindolecarboxylic acid derivative and its preparation
JPS5764639A (en) Novel stilbene derivative, its preparation, and medical composition containing the same as active ingredent
JPS55129275A (en) Farnesylacetic acid amide bearing piperazine ring or its salt
JPS5721400A (en) Novel fortimicin derivative
JPS5459223A (en) Preparation of azo compounds
JPS5511503A (en) Condensed heterocyclic compound
JPS5687541A (en) Preparation of amino acid ester
JPS56164144A (en) Preparation of novel aryloxyacid derivative
JPS56123972A (en) Preparation of 1,3-dialkyl-4-benzoyl-5-hydroxypyrazole compound
JPS5687542A (en) Preparation of amino acid ester
JPS5735561A (en) Novel alpha- mercaptomethyl acrylic acid derivative
JPS56128777A (en) Novel benzofuran derivative and muscle relaxant containing the same
JPS57112340A (en) Preparation of 6-fluoro-6-halogenobicyclo(3-1-o)hexane
JPS5785375A (en) Alkali metallic salt of 5-carboxyorotic acid
JPS5758640A (en) Hydroxycyclopentenone and its preparation
JPS5646889A (en) Gold compound and its preparation
JPS5549379A (en) Pyriod 3,2,1-ed quinoxaline-6-carboxylic acid derivative
JPS5629526A (en) Preparation of acylcyanide