JPS56128777A - Novel benzofuran derivative and muscle relaxant containing the same - Google Patents
Novel benzofuran derivative and muscle relaxant containing the sameInfo
- Publication number
- JPS56128777A JPS56128777A JP3031280A JP3031280A JPS56128777A JP S56128777 A JPS56128777 A JP S56128777A JP 3031280 A JP3031280 A JP 3031280A JP 3031280 A JP3031280 A JP 3031280A JP S56128777 A JPS56128777 A JP S56128777A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkyl
- muscle relaxant
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The titled compound expressed by formula I (R1 is 1W4C alkyl, 1W4C alkoxyl, phenyl or halogen; R2 and R3 are H or 1W4C alkyl; however, when either of R2 and R3 is H, the other is alkyl).
EXAMPLE: 2-Dimethylcarbamoylmethyl-3-methyl-5-methoxybenzo-[b]furan.
USE: A muscle relaxant having a muscle relaxing action, anticonvulsant, anti-inflammatory and analgesic actions with low toxicity.
PROCESS: A compound of formula I is reacted with an inorganic halogen compound to give an acid halide of formula IV, which is then reacted with an amine of formula III to give the compound of formula I. The reaction is preferably carried out in a solvent, e.g. methylene chloride or chloroform, in the presence of a catalyst, e.g. zinc chloride, pyridine or iodine.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3031280A JPS56128777A (en) | 1980-03-12 | 1980-03-12 | Novel benzofuran derivative and muscle relaxant containing the same |
GB8022461A GB2056441B (en) | 1979-07-26 | 1980-07-09 | Derivatives of benzo(b)furan and pharmaceutical compositions containing them |
DE3028291A DE3028291C2 (en) | 1979-07-26 | 1980-07-25 | 3-Methylbenzo [b] furyl-2-acetamides and medicinal products containing these compounds |
FR8016519A FR2462434A1 (en) | 1979-07-26 | 1980-07-25 | NOVEL BENZO (B) FURANES DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES |
CA000357015A CA1154027A (en) | 1979-07-26 | 1980-07-25 | Derivatives of benzo¬b| furan |
US06/172,949 US4297369A (en) | 1979-07-26 | 1980-07-28 | Certain muscle relaxant 3-methyl-2-benzofuran acetamides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3031280A JPS56128777A (en) | 1980-03-12 | 1980-03-12 | Novel benzofuran derivative and muscle relaxant containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56128777A true JPS56128777A (en) | 1981-10-08 |
JPS645033B2 JPS645033B2 (en) | 1989-01-27 |
Family
ID=12300260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3031280A Granted JPS56128777A (en) | 1979-07-26 | 1980-03-12 | Novel benzofuran derivative and muscle relaxant containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56128777A (en) |
-
1980
- 1980-03-12 JP JP3031280A patent/JPS56128777A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS645033B2 (en) | 1989-01-27 |
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