JPS56128777A - Novel benzofuran derivative and muscle relaxant containing the same - Google Patents

Novel benzofuran derivative and muscle relaxant containing the same

Info

Publication number
JPS56128777A
JPS56128777A JP3031280A JP3031280A JPS56128777A JP S56128777 A JPS56128777 A JP S56128777A JP 3031280 A JP3031280 A JP 3031280A JP 3031280 A JP3031280 A JP 3031280A JP S56128777 A JPS56128777 A JP S56128777A
Authority
JP
Japan
Prior art keywords
formula
compound
alkyl
muscle relaxant
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3031280A
Other languages
Japanese (ja)
Other versions
JPS645033B2 (en
Inventor
Hiroshi Takizawa
Yutaka Enomoto
Yoshimasa Ikuji
Takiyuki Hirayama
Tamotsu Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP3031280A priority Critical patent/JPS56128777A/en
Priority to GB8022461A priority patent/GB2056441B/en
Priority to DE3028291A priority patent/DE3028291C2/en
Priority to FR8016519A priority patent/FR2462434A1/en
Priority to CA000357015A priority patent/CA1154027A/en
Priority to US06/172,949 priority patent/US4297369A/en
Publication of JPS56128777A publication Critical patent/JPS56128777A/en
Publication of JPS645033B2 publication Critical patent/JPS645033B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound expressed by formula I (R1 is 1W4C alkyl, 1W4C alkoxyl, phenyl or halogen; R2 and R3 are H or 1W4C alkyl; however, when either of R2 and R3 is H, the other is alkyl).
EXAMPLE: 2-Dimethylcarbamoylmethyl-3-methyl-5-methoxybenzo-[b]furan.
USE: A muscle relaxant having a muscle relaxing action, anticonvulsant, anti-inflammatory and analgesic actions with low toxicity.
PROCESS: A compound of formula I is reacted with an inorganic halogen compound to give an acid halide of formula IV, which is then reacted with an amine of formula III to give the compound of formula I. The reaction is preferably carried out in a solvent, e.g. methylene chloride or chloroform, in the presence of a catalyst, e.g. zinc chloride, pyridine or iodine.
COPYRIGHT: (C)1981,JPO&Japio
JP3031280A 1979-07-26 1980-03-12 Novel benzofuran derivative and muscle relaxant containing the same Granted JPS56128777A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP3031280A JPS56128777A (en) 1980-03-12 1980-03-12 Novel benzofuran derivative and muscle relaxant containing the same
GB8022461A GB2056441B (en) 1979-07-26 1980-07-09 Derivatives of benzo(b)furan and pharmaceutical compositions containing them
DE3028291A DE3028291C2 (en) 1979-07-26 1980-07-25 3-Methylbenzo [b] furyl-2-acetamides and medicinal products containing these compounds
FR8016519A FR2462434A1 (en) 1979-07-26 1980-07-25 NOVEL BENZO (B) FURANES DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES
CA000357015A CA1154027A (en) 1979-07-26 1980-07-25 Derivatives of benzo¬b| furan
US06/172,949 US4297369A (en) 1979-07-26 1980-07-28 Certain muscle relaxant 3-methyl-2-benzofuran acetamides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3031280A JPS56128777A (en) 1980-03-12 1980-03-12 Novel benzofuran derivative and muscle relaxant containing the same

Publications (2)

Publication Number Publication Date
JPS56128777A true JPS56128777A (en) 1981-10-08
JPS645033B2 JPS645033B2 (en) 1989-01-27

Family

ID=12300260

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3031280A Granted JPS56128777A (en) 1979-07-26 1980-03-12 Novel benzofuran derivative and muscle relaxant containing the same

Country Status (1)

Country Link
JP (1) JPS56128777A (en)

Also Published As

Publication number Publication date
JPS645033B2 (en) 1989-01-27

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