JPS5528946A - 2-beta-thenoylamido-1,3,4-thiadiazole and its preparation - Google Patents
2-beta-thenoylamido-1,3,4-thiadiazole and its preparationInfo
- Publication number
- JPS5528946A JPS5528946A JP10213678A JP10213678A JPS5528946A JP S5528946 A JPS5528946 A JP S5528946A JP 10213678 A JP10213678 A JP 10213678A JP 10213678 A JP10213678 A JP 10213678A JP S5528946 A JPS5528946 A JP S5528946A
- Authority
- JP
- Japan
- Prior art keywords
- thiadiazole
- thenoylamido
- beta
- preparation
- thenolylamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:2-β-Thenolylamido-1,3,4-thiadiazole of formula.
USE: Remedy for malignant tumor such as leukemia, sarcoma, cancer,etc. Excellent anti-tumor activity and extremely low toxicity.
PROCESS: The title compound is prepared by reacting free β-thiophenic acid with 2-amino-1,3,4-thiadiazole at 10W250°C, under anhydrous conditions, in the presence or absence of a solvent, in the presence of a dehydrating agent such as N,N'-dicyclohexylcarbodiimide, etc. or a condensing agent such as dichlorocarbonic acid ester, etc.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10213678A JPS5528946A (en) | 1978-08-22 | 1978-08-22 | 2-beta-thenoylamido-1,3,4-thiadiazole and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10213678A JPS5528946A (en) | 1978-08-22 | 1978-08-22 | 2-beta-thenoylamido-1,3,4-thiadiazole and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5528946A true JPS5528946A (en) | 1980-02-29 |
Family
ID=14319343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10213678A Pending JPS5528946A (en) | 1978-08-22 | 1978-08-22 | 2-beta-thenoylamido-1,3,4-thiadiazole and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5528946A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59110294U (en) * | 1983-01-13 | 1984-07-25 | 三菱重工業株式会社 | bottom plug |
-
1978
- 1978-08-22 JP JP10213678A patent/JPS5528946A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59110294U (en) * | 1983-01-13 | 1984-07-25 | 三菱重工業株式会社 | bottom plug |
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