JPS56147774A - 5-fluorouracil derivative - Google Patents

5-fluorouracil derivative

Info

Publication number
JPS56147774A
JPS56147774A JP5138480A JP5138480A JPS56147774A JP S56147774 A JPS56147774 A JP S56147774A JP 5138480 A JP5138480 A JP 5138480A JP 5138480 A JP5138480 A JP 5138480A JP S56147774 A JPS56147774 A JP S56147774A
Authority
JP
Japan
Prior art keywords
fluorouracil
formula
fluorouracil derivative
derivative
lauroyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5138480A
Other languages
Japanese (ja)
Inventor
Yasuo Irie
Naohiko Yasuda
Hirokazu Ryono
Hirokazu Morisawa
Akihiro Yamazaki
Shigeru Toyoshima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP5138480A priority Critical patent/JPS56147774A/en
Publication of JPS56147774A publication Critical patent/JPS56147774A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A 5-fluorouracil derivative of formula I (R1 and R2 are 1W20C alkyl).
EXAMPLE: N1-(1,3-Di-n-lauroyloxy-2-propoxycarbonyl)-5-fluorouracil.
USE: A carcinostatic agent with low toxicity and good absorbability.
PROCESS: 5-Fluorouracil is reacted with a chloroformic ester of an α, α1-diglyceride expressed by formula II in the presence of a base, e.g. triethylamine, in a solvent, e.g. dimethylformamide, at 0W100°C to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP5138480A 1980-04-18 1980-04-18 5-fluorouracil derivative Pending JPS56147774A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5138480A JPS56147774A (en) 1980-04-18 1980-04-18 5-fluorouracil derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5138480A JPS56147774A (en) 1980-04-18 1980-04-18 5-fluorouracil derivative

Publications (1)

Publication Number Publication Date
JPS56147774A true JPS56147774A (en) 1981-11-16

Family

ID=12885445

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5138480A Pending JPS56147774A (en) 1980-04-18 1980-04-18 5-fluorouracil derivative

Country Status (1)

Country Link
JP (1) JPS56147774A (en)

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