JPS54100371A - Novel imidazole c-nucleoside derivative - Google Patents
Novel imidazole c-nucleoside derivativeInfo
- Publication number
- JPS54100371A JPS54100371A JP776178A JP776178A JPS54100371A JP S54100371 A JPS54100371 A JP S54100371A JP 776178 A JP776178 A JP 776178A JP 776178 A JP776178 A JP 776178A JP S54100371 A JPS54100371 A JP S54100371A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- lower alkanoyl
- aroyl
- nucleoside derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Imidazole C-nucleoside derivatives of formula I (R is H, lower alkanoyl, aroyl).
EXAMPLE: 2-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-5-hydroxyimidazole-4-carbo- xamide.
USE: Medicines used for metabolic antagonist having carcinostatic and antiviral activities.
PREPARATION: The reaction between an imide ester of formula II (A is lower alkoxy, benzylthio), its salt, preferably hydrochloride, or an ortho ester of formula III(B is lower alkyl) and aminomalon amide is conducted in an organic solvent as methanol or tetrahydrofuran at 0 - 100°C, when necessary, if R is lower alkanoyl or aroyl, the deacylation is effected, to produce the objective compound of formula I. The compound of formula II is obtained from a compound of formula IV (R' is lower alkanoyl).
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP776178A JPS54100371A (en) | 1978-01-25 | 1978-01-25 | Novel imidazole c-nucleoside derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP776178A JPS54100371A (en) | 1978-01-25 | 1978-01-25 | Novel imidazole c-nucleoside derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS54100371A true JPS54100371A (en) | 1979-08-08 |
Family
ID=11674663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP776178A Pending JPS54100371A (en) | 1978-01-25 | 1978-01-25 | Novel imidazole c-nucleoside derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS54100371A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4728729A (en) * | 1984-03-14 | 1988-03-01 | Sumitomo Pharmaceuticals Co., Ltd. | Cyanoimidazole nucleoside derivatives |
-
1978
- 1978-01-25 JP JP776178A patent/JPS54100371A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4728729A (en) * | 1984-03-14 | 1988-03-01 | Sumitomo Pharmaceuticals Co., Ltd. | Cyanoimidazole nucleoside derivatives |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS568352A (en) | Aminoalkylvenzene derivative | |
| JPS56131565A (en) | 4-substituted-2-oxoazetidine compound and its preparation | |
| JPS552602A (en) | 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester | |
| JPS54100371A (en) | Novel imidazole c-nucleoside derivative | |
| JPS5587777A (en) | Pyrimidine derivative, its preparation and antitumorigenic agent | |
| JPS5639062A (en) | Slufenamide derivative | |
| JPS5754175A (en) | Novel 3-aminoindazole derivative | |
| JPS57197256A (en) | Novel cyclohexanecarboxamide derivative and its preparation | |
| JPS5690067A (en) | Novel heterocyclic ring substituted phenylacetic acid derivative | |
| JPS5646873A (en) | 2-guanidinothiazole derivative and its preparation | |
| JPS5753480A (en) | Tetrahydro-1-alkylthiophenium derivative | |
| JPS5441874A (en) | Novel 2-substituted imidazole derivative | |
| JPS5742662A (en) | Benzoic acid amide derivative | |
| JPS572277A (en) | Quinoxalinone derivative, its preparation, and fungicide for agricultural and horticultural use | |
| JPS5473797A (en) | Pyride 3.2.1-jk carbazole derivative | |
| JPS554334A (en) | Pyranopyrazole derivative | |
| JPS5639074A (en) | Pyrimidine derivative | |
| IE46003L (en) | Morphinans | |
| JPS5551068A (en) | Novel hydantoin derivative, and antiphlogistic analgesic agent containing the same | |
| JPS55102567A (en) | Nicotinoylpantethine derivative | |
| JPS5646889A (en) | Gold compound and its preparation | |
| JPS56158756A (en) | S-methylcysteinamide, its salt and preparation thereof | |
| JPS5551069A (en) | Preparation of benzimidazole derivative | |
| JPS5649362A (en) | Thiocarbostyril derivative | |
| JPS5572173A (en) | Novel imidazoles |