JPS56158756A - S-methylcysteinamide, its salt and preparation thereof - Google Patents

S-methylcysteinamide, its salt and preparation thereof

Info

Publication number
JPS56158756A
JPS56158756A JP6326380A JP6326380A JPS56158756A JP S56158756 A JPS56158756 A JP S56158756A JP 6326380 A JP6326380 A JP 6326380A JP 6326380 A JP6326380 A JP 6326380A JP S56158756 A JPS56158756 A JP S56158756A
Authority
JP
Japan
Prior art keywords
formula
methyl
methylcysteinamide
salt
methylcysteine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6326380A
Other languages
Japanese (ja)
Other versions
JPS632257B2 (en
Inventor
Hiroshi Terayama
Yoshimi Morita
Kohei Umetsu
Tadashi Shirasaka
Retsu Shimooda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP6326380A priority Critical patent/JPS56158756A/en
Priority to PCT/JP1981/000107 priority patent/WO1981003330A1/en
Priority to DE8181901205T priority patent/DE3165832D1/en
Priority to EP81901205A priority patent/EP0051682B1/en
Priority to US06/336,377 priority patent/US4440788A/en
Publication of JPS56158756A publication Critical patent/JPS56158756A/en
Publication of JPS632257B2 publication Critical patent/JPS632257B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:An S-methylcysteinamide expressed by formula I (R1 is H, methyl or ethyl) and a salt thereof.
USE: A stimulating agent for the hepatic DNA synthesis and a remedy for hepatitis.
PROCESS: An S-methylcysteine of formula II (R2 is a protecting group of the amino group) or a reactive derivative thereof or an S-methylcysteine ester of formula III (R3 is lower alkyl), e.g. methyl ester of S-methyl-L-cysteine, is reacted with a compound of the formula R1NH2, e.g. ammonia, preferably in excess, usually in the presence of a base, e.g. triethylamine, in an organic solvent, e.g. methanol, at room temperature or under cooling. The protecting group of the amino group is then removed or the reaction mixture is neutralized if necessary to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP6326380A 1980-05-13 1980-05-13 S-methylcysteinamide, its salt and preparation thereof Granted JPS56158756A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP6326380A JPS56158756A (en) 1980-05-13 1980-05-13 S-methylcysteinamide, its salt and preparation thereof
PCT/JP1981/000107 WO1981003330A1 (en) 1980-05-13 1981-05-11 Cysteine derivative and production thereof
DE8181901205T DE3165832D1 (en) 1980-05-13 1981-05-11 Cysteine derivatives and process for their preparation
EP81901205A EP0051682B1 (en) 1980-05-13 1981-05-11 Cysteine derivatives and process for their preparation
US06/336,377 US4440788A (en) 1980-05-13 1981-05-11 Cysteine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6326380A JPS56158756A (en) 1980-05-13 1980-05-13 S-methylcysteinamide, its salt and preparation thereof

Publications (2)

Publication Number Publication Date
JPS56158756A true JPS56158756A (en) 1981-12-07
JPS632257B2 JPS632257B2 (en) 1988-01-18

Family

ID=13224215

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6326380A Granted JPS56158756A (en) 1980-05-13 1980-05-13 S-methylcysteinamide, its salt and preparation thereof

Country Status (1)

Country Link
JP (1) JPS56158756A (en)

Also Published As

Publication number Publication date
JPS632257B2 (en) 1988-01-18

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