JPS557225A - Preparation of propionic acid derivative - Google Patents

Preparation of propionic acid derivative

Info

Publication number
JPS557225A
JPS557225A JP7893678A JP7893678A JPS557225A JP S557225 A JPS557225 A JP S557225A JP 7893678 A JP7893678 A JP 7893678A JP 7893678 A JP7893678 A JP 7893678A JP S557225 A JPS557225 A JP S557225A
Authority
JP
Japan
Prior art keywords
compound
alcohol
aromatic
propionic acid
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7893678A
Other languages
Japanese (ja)
Other versions
JPS622570B2 (en
Inventor
Shiro Kudo
Tadashi Naraoka
Hideo Nishino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SANPO KAGAKU KENKIYUUJIYO KK
SANPO KAGAKU KENKYUSHO KK
Original Assignee
SANPO KAGAKU KENKIYUUJIYO KK
SANPO KAGAKU KENKYUSHO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SANPO KAGAKU KENKIYUUJIYO KK, SANPO KAGAKU KENKYUSHO KK filed Critical SANPO KAGAKU KENKIYUUJIYO KK
Priority to JP7893678A priority Critical patent/JPS557225A/en
Publication of JPS557225A publication Critical patent/JPS557225A/en
Publication of JPS622570B2 publication Critical patent/JPS622570B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare an aromatic-substituted propionic acid useful as an antipyretic analgesic agent, by reducing a compound obtained by the reaction of an aromatic acetyl compound with chloroform in the presence of a quaternary ammonium salt and an alcohol under basic conditions.
CONSTITUTION: The objective compound of formula IV (Ar is II, III, etc.) is obtained by the catalytic reduction of the compound IV, which is prepared by reacting a compound of formula I with chloroform under basic condition (e.g. in an aqueous solution of NaOH), in the presence of a quaternary ammonium salt, e.g. R4N+, shcu as benzyltriethylammonium chloride, and an alcohol such as a 4W8C aliphatic alcohol or an aromatic alcohol such as benzyl alcohol.
COPYRIGHT: (C)1980,JPO&Japio
JP7893678A 1978-06-28 1978-06-28 Preparation of propionic acid derivative Granted JPS557225A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7893678A JPS557225A (en) 1978-06-28 1978-06-28 Preparation of propionic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7893678A JPS557225A (en) 1978-06-28 1978-06-28 Preparation of propionic acid derivative

Publications (2)

Publication Number Publication Date
JPS557225A true JPS557225A (en) 1980-01-19
JPS622570B2 JPS622570B2 (en) 1987-01-20

Family

ID=13675752

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7893678A Granted JPS557225A (en) 1978-06-28 1978-06-28 Preparation of propionic acid derivative

Country Status (1)

Country Link
JP (1) JPS557225A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535056A (en) * 1978-09-04 1980-03-11 Hamari Yakuhin Kogyo Kk 3-substituted acetophenone and its preparation
JPS57128358A (en) * 1981-02-02 1982-08-09 Canon Inc Copying machine
JPS63264473A (en) * 1988-03-22 1988-11-01 Nisshin Flour Milling Co Ltd Production of glycidic acid

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535056A (en) * 1978-09-04 1980-03-11 Hamari Yakuhin Kogyo Kk 3-substituted acetophenone and its preparation
JPS57128358A (en) * 1981-02-02 1982-08-09 Canon Inc Copying machine
JPH035581B2 (en) * 1981-02-02 1991-01-25 Canon Kk
JPS63264473A (en) * 1988-03-22 1988-11-01 Nisshin Flour Milling Co Ltd Production of glycidic acid
JPH0223554B2 (en) * 1988-03-22 1990-05-24 Nisshin Flour Milling Co

Also Published As

Publication number Publication date
JPS622570B2 (en) 1987-01-20

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