JPS5535056A - 3-substituted acetophenone and its preparation - Google Patents

3-substituted acetophenone and its preparation

Info

Publication number
JPS5535056A
JPS5535056A JP10891478A JP10891478A JPS5535056A JP S5535056 A JPS5535056 A JP S5535056A JP 10891478 A JP10891478 A JP 10891478A JP 10891478 A JP10891478 A JP 10891478A JP S5535056 A JPS5535056 A JP S5535056A
Authority
JP
Japan
Prior art keywords
formula
ester
give
substituted
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10891478A
Other languages
Japanese (ja)
Inventor
Tamio Ueyama
Sueo Horiuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hamari Chemicals Ltd
Original Assignee
Hamari Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hamari Chemicals Ltd filed Critical Hamari Chemicals Ltd
Priority to JP10891478A priority Critical patent/JPS5535056A/en
Publication of JPS5535056A publication Critical patent/JPS5535056A/en
Pending legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A 3-subslituted acetophenone of formula I: (X's are H, or may form O atom).
EXAMPLE: 3-Benzylacetophenone.
USE: An intermediate for the synthesis of 2-(3-benzoylphenyl)-propionic acid, an antiphlogistic and analgesic.
PROCESS: A 3-substituted benzoic acid of formula II is reacted with a halogenating agent, e.g. thionyl chloride, to give an acid halide of formula III: (Y is halogen), which is coupled with a malonic diester to form a 3-substituted benzoylmalonic ester of formula IV: (R is lower alkyl group). The ester is decomposed in a mixture of acids, e.g. acetic and conc. sulfuric acids, under heating to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP10891478A 1978-09-04 1978-09-04 3-substituted acetophenone and its preparation Pending JPS5535056A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10891478A JPS5535056A (en) 1978-09-04 1978-09-04 3-substituted acetophenone and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10891478A JPS5535056A (en) 1978-09-04 1978-09-04 3-substituted acetophenone and its preparation

Publications (1)

Publication Number Publication Date
JPS5535056A true JPS5535056A (en) 1980-03-11

Family

ID=14496834

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10891478A Pending JPS5535056A (en) 1978-09-04 1978-09-04 3-substituted acetophenone and its preparation

Country Status (1)

Country Link
JP (1) JPS5535056A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01118139A (en) * 1987-10-30 1989-05-10 Konica Corp Photosensitive body

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116636A (en) * 1974-07-29 1976-02-10 Nisshin Flour Milling Co 22 * chikanariiru * puropionsanno seiho
JPS5165730A (en) * 1974-12-03 1976-06-07 Fujikawa Kk FUENIRUARUKANKARUBONSANJUDOTAINO SEIHO
JPS5236642A (en) * 1975-06-24 1977-03-22 Chinoin Gyogyszer Es Vegyeszet Production of substituted phenylalkyl carboxylic acid
JPS5334744A (en) * 1976-09-11 1978-03-31 Kyowa Hakko Kogyo Co Ltd Preparation of 2-(4-alkylphenyl)propionic acids
JPS557225A (en) * 1978-06-28 1980-01-19 Sanpo Kagaku Kenkyusho:Kk Preparation of propionic acid derivative

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116636A (en) * 1974-07-29 1976-02-10 Nisshin Flour Milling Co 22 * chikanariiru * puropionsanno seiho
JPS5165730A (en) * 1974-12-03 1976-06-07 Fujikawa Kk FUENIRUARUKANKARUBONSANJUDOTAINO SEIHO
JPS5236642A (en) * 1975-06-24 1977-03-22 Chinoin Gyogyszer Es Vegyeszet Production of substituted phenylalkyl carboxylic acid
JPS5334744A (en) * 1976-09-11 1978-03-31 Kyowa Hakko Kogyo Co Ltd Preparation of 2-(4-alkylphenyl)propionic acids
JPS557225A (en) * 1978-06-28 1980-01-19 Sanpo Kagaku Kenkyusho:Kk Preparation of propionic acid derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01118139A (en) * 1987-10-30 1989-05-10 Konica Corp Photosensitive body

Similar Documents

Publication Publication Date Title
JPS5731615A (en) Remedy for skin disease with keratinization
JPS5535056A (en) 3-substituted acetophenone and its preparation
JPS574987A (en) Pyridoindolecarboxylic acid derivative and its preparation
JPS5625133A (en) Preparation of fluorine-containing carboxylic acid ester
JPS54128567A (en) 1-substituted-4-acyl-2-pyrrolecarboxylic acid derivative
JPS5665838A (en) Preparation of beta-alkoxymethoxymethyl halide
JPS5513226A (en) Production of beta-(beta-chloroethylsulfonyl) propionic acid derivative
JPS54148758A (en) Alpha-thio-alpha-(2-fluoro-4-biphenylyl)carboxylic acid derivative
JPS5555135A (en) Preparation of d-2-(6-methoxy-2-naphthyl)-propionic acid
JPS5618942A (en) Novel terephthalic acid and its preparation
JPS55122784A (en) Novel acetic acid derivative and its preparation
JPS57167961A (en) Alpha-thio-alpha-(6-methoxy-naphth-2-yl)propionic acid ester
JPS5673064A (en) Isoquinoline derivative
JPS5572139A (en) Preparation of 4-allyloxy-3,5-disubstituted-phenylacetic acid
JPS5524142A (en) 2-oxo-3-4-(1,3-dioxo-2-isoindolinyl)phenylbutanamide and its preparation
JPS54117457A (en) Diacylsteroid derivative
JPS5479265A (en) 2-(2,2-dihalovinyl)thiophene and its preparation
JPS5645467A (en) Pantolactone derivative and its preparation
JPS5572140A (en) Preparation of 4-allyloxy-3,5-disubstituted-phenylacetic acid
JPS5745151A (en) Alpha-sulfonyl 2-fluoro-4-biphenylyl propionic acid derivative
JPS5527110A (en) Benzanilide derivative
JPS5721371A (en) Quinolinoneiminecarboxylic ester derivative, its preparation and anti-inflammatory and analgesic agent composition containing the same
JPS559039A (en) Novel propionic acid amide derivative and its preparation
JPS5559138A (en) Water-soluble acetylsalicilic acid, its production and preparation containing the same
JPS57145835A (en) Preparation of optically active naphthylpropionic acid