JPS55122784A - Novel acetic acid derivative and its preparation - Google Patents
Novel acetic acid derivative and its preparationInfo
- Publication number
- JPS55122784A JPS55122784A JP2999579A JP2999579A JPS55122784A JP S55122784 A JPS55122784 A JP S55122784A JP 2999579 A JP2999579 A JP 2999579A JP 2999579 A JP2999579 A JP 2999579A JP S55122784 A JPS55122784 A JP S55122784A
- Authority
- JP
- Japan
- Prior art keywords
- acetic acid
- compound
- acid derivative
- reducing
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An acetic acid derivative of formula I (A is O or S).
EXAMPLE: (5,6-Dihydro-6-hydroxybenzo[b]pyrido[3,2-f]thiepin-8-yl)-acetic acid.
USE: Antiphlogistic agent effective at a lower dose than conventional antiphlogistics.
PROCESS: The compound I is prepared by reducing the compound II with a reducing agent such as sodium borohydride in an ether. The compound II can be prepared e.g. by (1) reacting 2-halogeno-3-pyridylacetic acid ester with p-mercapto- (or hydroxy-)benzaldehyde, (2) reducing, halogenating and cyanating the reaction product, (3) removing the ester residue by hydrolysis, (4) closing the ring of the resulting 2-(4-cyanomethylphenylthio-) (or phenyxy-)3-pyridylacetic acid, and (5) hydrolyzing the product.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2999579A JPS55122784A (en) | 1979-03-16 | 1979-03-16 | Novel acetic acid derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2999579A JPS55122784A (en) | 1979-03-16 | 1979-03-16 | Novel acetic acid derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55122784A true JPS55122784A (en) | 1980-09-20 |
JPS6347714B2 JPS6347714B2 (en) | 1988-09-26 |
Family
ID=12291510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2999579A Granted JPS55122784A (en) | 1979-03-16 | 1979-03-16 | Novel acetic acid derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55122784A (en) |
-
1979
- 1979-03-16 JP JP2999579A patent/JPS55122784A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6347714B2 (en) | 1988-09-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS57109787A (en) | Pyrazoloindazole derivative | |
JPS55122784A (en) | Novel acetic acid derivative and its preparation | |
JPS54128567A (en) | 1-substituted-4-acyl-2-pyrrolecarboxylic acid derivative | |
JPS574987A (en) | Pyridoindolecarboxylic acid derivative and its preparation | |
JPS56125333A (en) | Phenylacetic acid derivative and its preparation | |
JPS55141457A (en) | Novel benzylidene derivative | |
JPS5498754A (en) | 3-hydroxy-3-bromomethylphthalide derivative | |
JPS5479265A (en) | 2-(2,2-dihalovinyl)thiophene and its preparation | |
JPS55153782A (en) | Dibenzo (b,f) thiepin derivative | |
JPS5673064A (en) | Isoquinoline derivative | |
JPS54144347A (en) | 3-(2-fluoro-4-biphenylyl)-2-butanone | |
JPS5735543A (en) | Novel phenylacetic acid derivative | |
JPS57106656A (en) | Phenylthiophenylacetic acid derivative | |
JPS54128599A (en) | Pyrrolobenzazepin derivative | |
JPS5545604A (en) | Nitro compound | |
JPS5699445A (en) | Preparation of novel pyruvic acid derivative | |
JPS5772963A (en) | Alpha-(2-pyridyl)arylacetaldehyde | |
JPS5625166A (en) | 5-fluorouracil derivative | |
JPS55104277A (en) | Dibenzothiepine derivative and its preparation | |
JPS5651441A (en) | O- n-allyl-2,6-dichloroanilino phenylacetic acid derivative and its preparation | |
JPS56127378A (en) | 2-alkoxyindolizine derivative and its preparation | |
JPS56123975A (en) | Novel indanmethanamine derivative | |
JPS5640673A (en) | Aminophenyltetrazole derivative and its salt | |
JPS56154439A (en) | Ml-236c derivative | |
JPS5572186A (en) | Dibenzothiepin derivative and its preparation |