JPS5640673A - Aminophenyltetrazole derivative and its salt - Google Patents
Aminophenyltetrazole derivative and its saltInfo
- Publication number
- JPS5640673A JPS5640673A JP11518179A JP11518179A JPS5640673A JP S5640673 A JPS5640673 A JP S5640673A JP 11518179 A JP11518179 A JP 11518179A JP 11518179 A JP11518179 A JP 11518179A JP S5640673 A JPS5640673 A JP S5640673A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- salt
- derivative
- tetrazole
- aminophenyltetrazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:An aminophenyltetrazole derivative of formula I (R is 1W4C alkyl), and its salt with a pharmacologically acceptable cation.
EXAMPLE: 5-(2-Ethyloxalylaminophenyl)tetrazole.
USE: A low-toxic anti-allergic agent.
PROCESS: The compound of formula I is prepared by reacting 5-(2-aminophenyl) tetrazole of formula II (a novel compound) with an oxalyl derivative of formula III (A is halogen or 1W4C alkoxy; R is 1W4C alkyl) in a proper solvent, and if necessary, converting the product to a salt with a pharmacologically acceptable cation. The novel compound of formula II can be obtained by reducing 5-(2-nitrophenyl)tetrazole with hydrochloric acid and tin.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11518179A JPS591704B2 (en) | 1979-09-10 | 1979-09-10 | Aminophenyl tetrazole derivatives and their salts |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11518179A JPS591704B2 (en) | 1979-09-10 | 1979-09-10 | Aminophenyl tetrazole derivatives and their salts |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5640673A true JPS5640673A (en) | 1981-04-16 |
JPS591704B2 JPS591704B2 (en) | 1984-01-13 |
Family
ID=14656352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11518179A Expired JPS591704B2 (en) | 1979-09-10 | 1979-09-10 | Aminophenyl tetrazole derivatives and their salts |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS591704B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4778816A (en) * | 1984-12-24 | 1988-10-18 | Wakamoto Pharmaceutical Co., Ltd. | Anti-asthmatic composition and process for preparing the same |
US4795754A (en) * | 1986-08-12 | 1989-01-03 | Wakamoto Pharmaceutical Co., Ltd. | 3-(1H-tetrazol-5-y1)oxanilic acid and salts thereof and pharmaceutical compositions containing them |
-
1979
- 1979-09-10 JP JP11518179A patent/JPS591704B2/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4778816A (en) * | 1984-12-24 | 1988-10-18 | Wakamoto Pharmaceutical Co., Ltd. | Anti-asthmatic composition and process for preparing the same |
US4795754A (en) * | 1986-08-12 | 1989-01-03 | Wakamoto Pharmaceutical Co., Ltd. | 3-(1H-tetrazol-5-y1)oxanilic acid and salts thereof and pharmaceutical compositions containing them |
Also Published As
Publication number | Publication date |
---|---|
JPS591704B2 (en) | 1984-01-13 |
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