JPS5452087A - Cytidine derivative and its prepareation - Google Patents

Cytidine derivative and its prepareation

Info

Publication number
JPS5452087A
JPS5452087A JP11832277A JP11832277A JPS5452087A JP S5452087 A JPS5452087 A JP S5452087A JP 11832277 A JP11832277 A JP 11832277A JP 11832277 A JP11832277 A JP 11832277A JP S5452087 A JPS5452087 A JP S5452087A
Authority
JP
Japan
Prior art keywords
salt
iminopyrimidine
arabinofuranosyl
dihydro
prepareation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11832277A
Other languages
Japanese (ja)
Inventor
Kazumi Inoue
Kazuhiko Kondo
Akihiro Kojima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP11832277A priority Critical patent/JPS5452087A/en
Publication of JPS5452087A publication Critical patent/JPS5452087A/en
Pending legal-status Critical Current

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:1-β-D-arabinofuranosy1-2-substituted-1,4-dihydro-iminopyrimidine salt of formula I (R is aralkyl, pyridylalkyl; X is anion residue of a pharmacologically permissible acid).
EXAMPLE: 1-β-D-arabinofuranosyl-2-benzylamino-1,4-dihydro-4-iminopyrimidine hydrochloric acid salt 1/2 hydrate.
USE: Anti-viral agent. Stable in aqueous solution. Easily be converted to another pharmacologically permissible inorganic or organic salt by ion exchange resin treatment, etc.
PROCESS: The compound I is prepared by reacting an amine II with 2,2'-anhydro- 1-(β-D-arabinofuranosyl) cytosine salt III in a solvent such as methanol, at room temperature
COPYRIGHT: (C)1979,JPO&Japio
JP11832277A 1977-09-30 1977-09-30 Cytidine derivative and its prepareation Pending JPS5452087A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11832277A JPS5452087A (en) 1977-09-30 1977-09-30 Cytidine derivative and its prepareation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11832277A JPS5452087A (en) 1977-09-30 1977-09-30 Cytidine derivative and its prepareation

Publications (1)

Publication Number Publication Date
JPS5452087A true JPS5452087A (en) 1979-04-24

Family

ID=14733790

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11832277A Pending JPS5452087A (en) 1977-09-30 1977-09-30 Cytidine derivative and its prepareation

Country Status (1)

Country Link
JP (1) JPS5452087A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107216362A (en) * 2017-06-12 2017-09-29 山东大学 A kind of cytarabine amphipathic small molecules prodrug and its preparation method and application

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107216362A (en) * 2017-06-12 2017-09-29 山东大学 A kind of cytarabine amphipathic small molecules prodrug and its preparation method and application

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