JPS55167281A - Preparation of piperazine derivative or its salt - Google Patents
Preparation of piperazine derivative or its saltInfo
- Publication number
- JPS55167281A JPS55167281A JP7423879A JP7423879A JPS55167281A JP S55167281 A JPS55167281 A JP S55167281A JP 7423879 A JP7423879 A JP 7423879A JP 7423879 A JP7423879 A JP 7423879A JP S55167281 A JPS55167281 A JP S55167281A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- compound
- formula
- piperazine derivative
- benzthiazolinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
Abstract
PURPOSE: To obtain the titled compound, useful as a medicine, and having an anti- inflammatory action, by reducing a specific compound prepared through the reaction of a haloacetic acid with 3-(1-piperazinyl)carbonyl lower alkyl-2-benzthiazolinone.
CONSTITUTION: A compound of formula I (X is H or halogen; A is lower alkylene group; R is a carboxy group which may be protected) or its salt is reduced with an alkali metal borohydride, e.g. sodium borohydride, in a solvent, e.g. methanol or acetone, at room temperature or under cooling or heating to give a piperazine derivative of formula II or its salt. The compound of formula I can be prepared by reacting a haloacetic acid with 3-(1-piperazinyl)carbonyl lower alkyl-2-benzthiazolinone or its salt.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7423879A JPS55167281A (en) | 1979-06-12 | 1979-06-12 | Preparation of piperazine derivative or its salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7423879A JPS55167281A (en) | 1979-06-12 | 1979-06-12 | Preparation of piperazine derivative or its salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS55167281A true JPS55167281A (en) | 1980-12-26 |
Family
ID=13541372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7423879A Pending JPS55167281A (en) | 1979-06-12 | 1979-06-12 | Preparation of piperazine derivative or its salt |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55167281A (en) |
-
1979
- 1979-06-12 JP JP7423879A patent/JPS55167281A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS55167281A (en) | Preparation of piperazine derivative or its salt | |
| JPS5559127A (en) | Novel intermediate compound for producing prostanoids and its manufacture | |
| JPS55145648A (en) | New derivative of anthranylic acid | |
| JPS5395912A (en) | New derivative of active acetic acid ulceratives | |
| JPS5655383A (en) | Amizine derivative and its preparation | |
| JPS5640643A (en) | Preparation of ethyl trans-2-decen-4-ynoate | |
| JPS5618933A (en) | Dihydroxy aluminum salt of substituted acetic acid and its preparation | |
| JPS57144253A (en) | Preparation of crude aminoalkylthiol | |
| JPS55141457A (en) | Novel benzylidene derivative | |
| JPS5334703A (en) | Preparation of methyl bromide from hydrobromic acid | |
| JPS5649398A (en) | Preparation of 1-beta-d-arabinofuranosyl-2,2'-cyclothymine | |
| JPS5788191A (en) | Beta-l-rhamnopyranoside derivative | |
| JPS567752A (en) | Preparation of 2- sulfophenylhydrazino -butane diacid derivative | |
| JPS5616464A (en) | Production of alpha-methylthio-4-hydroxyphenylacetic acid | |
| JPS55160796A (en) | Preparation of n6-alkyl cordycepin | |
| JPS543021A (en) | Novel derivative of glutamic acid and its preparation | |
| JPS5651441A (en) | O- n-allyl-2,6-dichloroanilino phenylacetic acid derivative and its preparation | |
| JPS5481253A (en) | 2-methyl-2-hydroxyperhydrotriquinacene | |
| JPS5452087A (en) | Cytidine derivative and its prepareation | |
| JPS54106498A (en) | Carbostyril derivative | |
| JPS55167274A (en) | Forphenicine derivative and its preparation | |
| JPS5615265A (en) | Preparation of indole derivative | |
| JPS55127365A (en) | Preparation of substituted indole | |
| JPS549204A (en) | Preparation of aminocarboxylic acid ester of secondary or tertiary alcohol | |
| JPS55162721A (en) | Preparation of alcohol |