JPS5632472A - Preparation of chemotherapeutically useful salicylic acid double salt - Google Patents
Preparation of chemotherapeutically useful salicylic acid double saltInfo
- Publication number
- JPS5632472A JPS5632472A JP10869479A JP10869479A JPS5632472A JP S5632472 A JPS5632472 A JP S5632472A JP 10869479 A JP10869479 A JP 10869479A JP 10869479 A JP10869479 A JP 10869479A JP S5632472 A JPS5632472 A JP S5632472A
- Authority
- JP
- Japan
- Prior art keywords
- salicylic acid
- methyl cellosolve
- double salt
- solution
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the titled compound having germicidal and antitumor activities with low toxicity readily, by dissolving a specific compound in methyl cellosolve, and reacting the cmpound with a salicylic acid solution in methyl cellosolve under given conditions.
CONSTITUTION: One molar amount of a compound expressed by the formula (R is H or dichloroacetyl chloride group; R1 and R2 are diazosulfamide group) is dissolved in ethylene glycol monomethyl ether (methyl cellosolve), and an equal amount of a solution of salicylic acid or a derivative thereof in methyl cellosolve is added to the solution and reacted under neutral or alkaline conditions to afford a salicylic acid double salt.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10869479A JPS5632472A (en) | 1979-08-28 | 1979-08-28 | Preparation of chemotherapeutically useful salicylic acid double salt |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10869479A JPS5632472A (en) | 1979-08-28 | 1979-08-28 | Preparation of chemotherapeutically useful salicylic acid double salt |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5632472A true JPS5632472A (en) | 1981-04-01 |
Family
ID=14491266
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10869479A Pending JPS5632472A (en) | 1979-08-28 | 1979-08-28 | Preparation of chemotherapeutically useful salicylic acid double salt |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5632472A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5885588A (en) * | 1981-11-16 | 1983-05-21 | Nec Corp | Wavelength multiplex light amplifying device |
US4863910A (en) * | 1986-05-20 | 1989-09-05 | Takeo Takayanagi | Complexes of AZO compounds and/or their salts and an antitumor agent and a method for reducing the growth of tumors |
US4956457A (en) * | 1986-05-20 | 1990-09-11 | Takeo Takayanagi | Disazo disulfonamides compounds |
-
1979
- 1979-08-28 JP JP10869479A patent/JPS5632472A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5885588A (en) * | 1981-11-16 | 1983-05-21 | Nec Corp | Wavelength multiplex light amplifying device |
US4863910A (en) * | 1986-05-20 | 1989-09-05 | Takeo Takayanagi | Complexes of AZO compounds and/or their salts and an antitumor agent and a method for reducing the growth of tumors |
US4956457A (en) * | 1986-05-20 | 1990-09-11 | Takeo Takayanagi | Disazo disulfonamides compounds |
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