JPS55115843A - Preparation of delta-hydroxy-ketone - Google Patents
Preparation of delta-hydroxy-ketoneInfo
- Publication number
- JPS55115843A JPS55115843A JP2333479A JP2333479A JPS55115843A JP S55115843 A JPS55115843 A JP S55115843A JP 2333479 A JP2333479 A JP 2333479A JP 2333479 A JP2333479 A JP 2333479A JP S55115843 A JPS55115843 A JP S55115843A
- Authority
- JP
- Japan
- Prior art keywords
- amidated
- keto
- delta
- ketone
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the title substance, an important intermediate for chromans, in high yield, by hydrolyzing the reaction product between the amidated δ-keto- carboxylic acid and methylmagnesium chloride.
CONSTITUTION: A δ-keto-carboxylic acid of formulaI (R is hydrocarbon group) is amidated with phosphoric triamide to form an acid amide of formula II (R' and R" are H or hydrocarbon groups, or may be linked to each other), which is reacted with methylmagnesium chloride in an aliphatic ether at 0W35°C at a high reaction rate. The reaction product is then hydrolyzed to give the objective substance of formula III in high yield.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2333479A JPS55115843A (en) | 1979-03-02 | 1979-03-02 | Preparation of delta-hydroxy-ketone |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2333479A JPS55115843A (en) | 1979-03-02 | 1979-03-02 | Preparation of delta-hydroxy-ketone |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55115843A true JPS55115843A (en) | 1980-09-06 |
Family
ID=12107673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2333479A Pending JPS55115843A (en) | 1979-03-02 | 1979-03-02 | Preparation of delta-hydroxy-ketone |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55115843A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106673976A (en) * | 2016-12-20 | 2017-05-17 | 福建师范大学 | Preparation method for alpha-hydroxy cyclo-pentadecanone |
-
1979
- 1979-03-02 JP JP2333479A patent/JPS55115843A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106673976A (en) * | 2016-12-20 | 2017-05-17 | 福建师范大学 | Preparation method for alpha-hydroxy cyclo-pentadecanone |
CN106673976B (en) * | 2016-12-20 | 2019-06-14 | 福建师范大学 | A kind of preparation method of Alpha-hydroxy cyclopentadecanone |
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