JPS5585552A - New lactyltetrapeptide - Google Patents

New lactyltetrapeptide

Info

Publication number
JPS5585552A
JPS5585552A JP14727579A JP14727579A JPS5585552A JP S5585552 A JPS5585552 A JP S5585552A JP 14727579 A JP14727579 A JP 14727579A JP 14727579 A JP14727579 A JP 14727579A JP S5585552 A JPS5585552 A JP S5585552A
Authority
JP
Japan
Prior art keywords
compound
protected
substance
new
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14727579A
Other languages
Japanese (ja)
Other versions
JPS6318598B2 (en
Inventor
Yoshio Kuroda
Hideko Iguchi
Masanobu Kosaka
Hatsuo Aoki
Hiroshi Imanaka
Yoshihiko Kitaura
Osamu Nakaguchi
Keiji Henmi
Matsuhiko Araya
Shuichi Takeno
Tatsu Okada
Hirokazu Tanaka
Shinji Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB7844364A external-priority patent/GB2007791B/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS5585552A publication Critical patent/JPS5585552A/en
Publication of JPS6318598B2 publication Critical patent/JPS6318598B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:Lactyl-alanyl-glutamyl-mesodiaminopimelyl-glycine I and its pharmaceutically permissible acid-addition salt. USE:An immune response accelerator, a reticulo-endothelial system exasperator, an interferon producer, a juvenescent substance, a phylaxis substance, a carcinostatic substance, etc. PROCESS:A compound II (R<4> is protected OH; R<5> is OH-protecting goup) is reacted with a compound III [R<1> is (protected) OH or (protected) hydrazino; R<2a> is NH2- protecting group; R<3> is (protected) OH] to give the compound I-1. The reaction is carried out in a solvent in the presence of a condensing agent. The protecting group of the product is removed by e.g. reduction, hydrolysis, etc., to give the compound I. The compound I can be also obtained by culturing streptomyces in the fermentation method. Some of the compounds II and III are new compounds.
JP14727579A 1978-11-14 1979-11-14 New lactyltetrapeptide Granted JPS5585552A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7844364A GB2007791B (en) 1977-11-16 1978-11-14 Pipe fitting

Publications (2)

Publication Number Publication Date
JPS5585552A true JPS5585552A (en) 1980-06-27
JPS6318598B2 JPS6318598B2 (en) 1988-04-19

Family

ID=10501025

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14727579A Granted JPS5585552A (en) 1978-11-14 1979-11-14 New lactyltetrapeptide

Country Status (1)

Country Link
JP (1) JPS5585552A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57108050A (en) * 1980-11-11 1982-07-05 Fujisawa Pharmaceut Co Ltd Novel peptide and its preparation
JPS57114556A (en) * 1980-10-27 1982-07-16 Fujisawa Pharmaceut Co Ltd Novel peptide compound and its preparation
JPS57136555A (en) * 1980-12-31 1982-08-23 Fujisawa Pharmaceut Co Ltd Novel peptide and its preparation
JPS57140751A (en) * 1981-01-29 1982-08-31 Fujisawa Pharmaceut Co Ltd Novel peptide, its preparation and use
JPS57145845A (en) * 1981-01-29 1982-09-09 Fujisawa Pharmaceut Co Ltd Novel peptide and its preparation
DE3440621A1 (en) * 1983-11-10 1985-05-23 Fujisawa Pharmaceutical Co., Ltd., Osaka PHARMACEUTICAL COMPOSITION FOR CONTROLLING VIRUS INFECTIONS AND THEIR USE
JP2002539186A (en) * 1999-03-17 2002-11-19 ノボ ノルディスク アクティーゼルスカブ Acylation method of peptide and novel acylating agent
US9562910B2 (en) 2002-09-25 2017-02-07 Novo Nordisk A/S Method for producing acylated peptides

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57114556A (en) * 1980-10-27 1982-07-16 Fujisawa Pharmaceut Co Ltd Novel peptide compound and its preparation
JPH0325437B2 (en) * 1980-10-27 1991-04-05 Fujisawa Pharmaceutical Co
JPS57108050A (en) * 1980-11-11 1982-07-05 Fujisawa Pharmaceut Co Ltd Novel peptide and its preparation
JPS57136555A (en) * 1980-12-31 1982-08-23 Fujisawa Pharmaceut Co Ltd Novel peptide and its preparation
JPS57140751A (en) * 1981-01-29 1982-08-31 Fujisawa Pharmaceut Co Ltd Novel peptide, its preparation and use
JPS57145845A (en) * 1981-01-29 1982-09-09 Fujisawa Pharmaceut Co Ltd Novel peptide and its preparation
DE3440621A1 (en) * 1983-11-10 1985-05-23 Fujisawa Pharmaceutical Co., Ltd., Osaka PHARMACEUTICAL COMPOSITION FOR CONTROLLING VIRUS INFECTIONS AND THEIR USE
JP2002539186A (en) * 1999-03-17 2002-11-19 ノボ ノルディスク アクティーゼルスカブ Acylation method of peptide and novel acylating agent
JP4949557B2 (en) * 1999-03-17 2012-06-13 ノヴォ ノルディスク アー／エス Peptide acylation method and novel acylating agent
US9562910B2 (en) 2002-09-25 2017-02-07 Novo Nordisk A/S Method for producing acylated peptides

Also Published As

Publication number Publication date
JPS6318598B2 (en) 1988-04-19

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