DK0422154T3 - Terapeutisk anvendelse af 5-HT3-receptorantagonister - Google Patents

Terapeutisk anvendelse af 5-HT3-receptorantagonister

Info

Publication number
DK0422154T3
DK0422154T3 DK90905482.7T DK90905482T DK0422154T3 DK 0422154 T3 DK0422154 T3 DK 0422154T3 DK 90905482 T DK90905482 T DK 90905482T DK 0422154 T3 DK0422154 T3 DK 0422154T3
Authority
DK
Denmark
Prior art keywords
receptor antagonists
therapeutic use
disorders
agoraphobia
useful
Prior art date
Application number
DK90905482.7T
Other languages
English (en)
Inventor
Alberto Azcona
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898909147A external-priority patent/GB8909147D0/en
Priority claimed from GB898916602A external-priority patent/GB8916602D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of DK0422154T3 publication Critical patent/DK0422154T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK90905482.7T 1989-04-21 1990-04-06 Terapeutisk anvendelse af 5-HT3-receptorantagonister DK0422154T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898909147A GB8909147D0 (en) 1989-04-21 1989-04-21 Improvements in or relating to organic compounds
GB898916602A GB8916602D0 (en) 1989-07-20 1989-07-20 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
DK0422154T3 true DK0422154T3 (da) 1994-03-07

Family

ID=26295258

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90905482.7T DK0422154T3 (da) 1989-04-21 1990-04-06 Terapeutisk anvendelse af 5-HT3-receptorantagonister

Country Status (10)

Country Link
EP (1) EP0422154B1 (da)
JP (1) JPH0669963B2 (da)
KR (1) KR920700034A (da)
AT (1) ATE97803T1 (da)
AU (1) AU631632B2 (da)
CA (1) CA2031214A1 (da)
DE (1) DE69004924T2 (da)
DK (1) DK0422154T3 (da)
ES (1) ES2061024T3 (da)
WO (1) WO1990012569A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5276050A (en) * 1989-08-01 1994-01-04 Glaxo Group Limited Medicaments
US5225407A (en) * 1990-02-22 1993-07-06 Glaxo Group Limited 5-HT3 receptor antagonists for the treatment of autism
US5508287A (en) * 1992-02-24 1996-04-16 Merrell Pharmaceuticals Inc. 2,6-methano-2H-quinolizin derivative as 5-HT3 -receptor antagonist
EP0641198A1 (en) * 1992-05-23 1995-03-08 Smithkline Beecham Plc Medicaments for the treatment of anxiety
WO2011082266A2 (en) 2009-12-30 2011-07-07 Arqule, Inc. Substituted heterocyclic compounds
US20110288115A1 (en) * 2010-05-24 2011-11-24 Avmedis Llc Treatment of vagally-mediated spectrum disorders
JP5387648B2 (ja) 2011-10-14 2014-01-15 株式会社デンソー 指針表示装置

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1365296A (en) * 1970-10-30 1974-08-29 Unilever Ltd Dentifrice compositions
EP0099194A3 (en) * 1982-07-03 1984-04-11 Beecham Group Plc Novel benzamides
FI84349C (fi) * 1984-01-25 1991-11-25 Glaxo Group Ltd Foerfarande foer framstaellning av en farmakologiskt vaerdefull foerening.
DE3680123D1 (en) 1985-01-23 1991-08-14 Glaxo Group Ltd Tetrahydrocarbazolonderivate.
DE3688296T2 (de) * 1985-03-14 1993-11-04 Beecham Group Plc Arzneimittel zur behandlung von erbrechen.
GB8518743D0 (en) 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518658D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Medicaments
GB8518741D0 (en) 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518745D0 (en) 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
EP0212398A2 (de) 1985-08-21 1987-03-04 Siemens Aktiengesellschaft Verfahren zur Erkennung von Mehrfrequenzcodesignalen mit überlagerten Störsignalen
IL80707A (en) 1985-12-23 1991-03-10 Hughes Aircraft Co Gaseous discharge device simmering circuit
DK134687A (da) 1986-03-17 1987-09-18 Glaxo Group Ltd Indolderivater
GB8701494D0 (en) 1987-01-23 1987-02-25 Glaxo Group Ltd Chemical compounds
GB8617994D0 (en) 1986-07-23 1986-08-28 Glaxo Group Ltd Heterocyclic compounds
EP0254584B1 (en) * 1986-07-25 1992-10-07 Beecham Group Plc Azabicyclic compounds, process for their preparation, and their pharmaceutical use
NL8701682A (nl) 1986-07-30 1988-02-16 Sandoz Ag Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
GB8623819D0 (en) 1986-10-03 1986-11-05 Glaxo Group Ltd Heterocyclic compounds
JP2765845B2 (ja) 1986-11-21 1998-06-18 グラクソ、グループ、リミテッド 中止症候群の予防の治療薬
GR871809B (en) 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
PH23937A (en) * 1986-12-16 1990-01-23 Robins Co Inc A H Anxiolytic-n-(1-azabicyclo(2.2.2.)oct-3-yl)benzamides and thiobenzamides
GB8806990D0 (en) 1988-03-23 1988-04-27 Beecham Group Plc Novel compounds
DE3876006T2 (de) 1987-04-14 1993-03-25 Glaxo Group Ltd Keton-derivate.
DE3827253A1 (de) 1987-08-20 1989-03-02 Sandoz Ag Ester und amide von cyclischen carbonsaeuren und cyclischen alkoholen und aminen sowie verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
GB8720693D0 (en) 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
ATE111910T1 (de) 1987-09-03 1994-10-15 Glaxo Group Ltd Lactamderivate.
GB8720805D0 (en) * 1987-09-04 1987-10-14 Naylor R J 2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides
JPH01258673A (ja) 1987-10-22 1989-10-16 Glaxo Group Ltd ケトン誘導体
DE3740984A1 (de) * 1987-12-03 1989-06-15 Sandoz Ag N-oxide von heterocyclischen carbonsaeurederivaten bzw. verfahren zu deren herstellung und deren verwendung
GB8802127D0 (en) 1988-02-01 1988-03-02 Glaxo Group Ltd Chemical compounds
DE68924545T2 (de) * 1988-02-23 1996-03-21 Merrell Dow Pharma Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln.
EP0329904A1 (en) * 1988-02-23 1989-08-30 Merrell Dow Pharmaceuticals Inc. Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of anxiety
JPH0249772A (ja) 1988-04-07 1990-02-20 Glaxo Group Ltd イミダゾール誘導体
US4863921A (en) 1988-04-27 1989-09-05 Rorer Pharmaceutical Corporation Dibenzofurancarboxamides and their pharmaceutical compositions and methods
EP0339959A3 (en) 1988-04-27 1991-03-20 Glaxo Group Limited Lactam derivatives
GB8812636D0 (en) 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
GB8814277D0 (en) 1988-06-16 1988-07-20 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
DE69004924T2 (de) 1994-05-19
KR920700034A (ko) 1992-02-19
CA2031214A1 (en) 1990-10-22
EP0422154A1 (en) 1991-04-17
WO1990012569A1 (en) 1990-11-01
AU5415890A (en) 1990-11-16
ES2061024T3 (es) 1994-12-01
DE69004924D1 (de) 1994-01-13
EP0422154B1 (en) 1993-12-01
ATE97803T1 (de) 1993-12-15
AU631632B2 (en) 1992-12-03
JPH03505881A (ja) 1991-12-19
JPH0669963B2 (ja) 1994-09-07

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