DK169335B1 - N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum - Google Patents

N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum Download PDF

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Publication number
DK169335B1
DK169335B1 DK340188A DK340188A DK169335B1 DK 169335 B1 DK169335 B1 DK 169335B1 DK 340188 A DK340188 A DK 340188A DK 340188 A DK340188 A DK 340188A DK 169335 B1 DK169335 B1 DK 169335B1
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DK
Denmark
Prior art keywords
compound
formula
acid addition
pharmaceutical
addition salt
Prior art date
Application number
DK340188A
Other languages
Danish (da)
English (en)
Other versions
DK340188A (da
DK340188D0 (da
Inventor
Walter Haefliger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK340188D0 publication Critical patent/DK340188D0/da
Publication of DK340188A publication Critical patent/DK340188A/da
Application granted granted Critical
Publication of DK169335B1 publication Critical patent/DK169335B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
DK340188A 1987-06-23 1988-06-21 N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum DK169335B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3720656 1987-06-23
DE3720656 1987-06-23

Publications (3)

Publication Number Publication Date
DK340188D0 DK340188D0 (da) 1988-06-21
DK340188A DK340188A (da) 1988-12-24
DK169335B1 true DK169335B1 (da) 1994-10-10

Family

ID=6330087

Family Applications (1)

Application Number Title Priority Date Filing Date
DK340188A DK169335B1 (da) 1987-06-23 1988-06-21 N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum

Country Status (28)

Country Link
US (1) US5075318A (it)
JP (1) JPH0670052B2 (it)
KR (1) KR970001527B1 (it)
AT (1) AT395242B (it)
AU (1) AU615657B2 (it)
BE (1) BE1004034A3 (it)
CA (1) CA1302404C (it)
CH (1) CH674646A5 (it)
CY (1) CY1752A (it)
DK (1) DK169335B1 (it)
ES (1) ES2010282A6 (it)
FI (1) FI88302C (it)
FR (1) FR2617166B1 (it)
GB (1) GB2206115B (it)
GR (1) GR1002318B (it)
HK (1) HK2794A (it)
HU (2) HU203097B (it)
IE (1) IE60550B1 (it)
IL (1) IL86820A (it)
IT (1) IT1219652B (it)
LU (1) LU87251A1 (it)
MY (1) MY103584A (it)
NL (1) NL8801597A (it)
NZ (1) NZ225112A (it)
PH (1) PH24690A (it)
PT (1) PT87781B (it)
SE (1) SE467925B (it)
ZA (1) ZA884505B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
JP3630888B2 (ja) * 1996-10-31 2005-03-23 株式会社ニデック レンズ搬送装置と眼鏡レンズを搬送するための眼鏡レンズ用固定カップ及びレンズ搬送方法
WO2010045342A1 (en) 2008-10-17 2010-04-22 Wisconsin Alumni Research Foundation Method of making biologically active alpha-beta peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.

Also Published As

Publication number Publication date
HU211651A9 (en) 1995-12-28
JPS6422876A (en) 1989-01-25
GR1002318B (el) 1996-05-13
KR970001527B1 (ko) 1997-02-11
NL8801597A (nl) 1989-01-16
FR2617166B1 (fr) 1992-07-17
GB2206115A (en) 1988-12-29
LU87251A1 (fr) 1989-03-08
FI88302C (fi) 1993-04-26
JPH0670052B2 (ja) 1994-09-07
IT1219652B (it) 1990-05-24
SE8802323D0 (sv) 1988-06-21
ZA884505B (en) 1990-02-28
IL86820A (en) 1991-07-18
AU1819488A (en) 1989-01-05
GB2206115B (en) 1991-04-03
CY1752A (en) 1994-06-03
AU615657B2 (en) 1991-10-10
ES2010282A6 (es) 1989-11-01
DK340188A (da) 1988-12-24
CA1302404C (en) 1992-06-02
IE60550B1 (en) 1994-07-27
HU203097B (en) 1991-05-28
PT87781B (pt) 1992-10-30
AT395242B (de) 1992-10-27
DK340188D0 (da) 1988-06-21
HK2794A (en) 1994-01-21
PH24690A (en) 1990-09-07
SE8802323L (sv) 1988-12-24
SE467925B (sv) 1992-10-05
GB8814615D0 (en) 1988-07-27
MY103584A (en) 1993-08-28
FI883008A0 (fi) 1988-06-22
GR880100401A (el) 1989-03-08
FI88302B (fi) 1993-01-15
IE881867L (en) 1988-12-23
KR890000479A (ko) 1989-03-14
IT8848097A0 (it) 1988-06-17
FI883008A (fi) 1988-12-24
ATA161788A (de) 1992-03-15
US5075318A (en) 1991-12-24
NZ225112A (en) 1991-03-26
CH674646A5 (it) 1990-06-29
PT87781A (pt) 1989-05-31
HUT50174A (en) 1989-12-28
FR2617166A1 (fr) 1988-12-30
BE1004034A3 (fr) 1992-09-15
IL86820A0 (en) 1988-11-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed