DK168708B1 - Fremgangsmåde til fremstilling af N7-amidinosubstituerede mitomycin C-derivater - Google Patents
Fremgangsmåde til fremstilling af N7-amidinosubstituerede mitomycin C-derivater Download PDFInfo
- Publication number
- DK168708B1 DK168708B1 DK193786A DK193786A DK168708B1 DK 168708 B1 DK168708 B1 DK 168708B1 DK 193786 A DK193786 A DK 193786A DK 193786 A DK193786 A DK 193786A DK 168708 B1 DK168708 B1 DK 168708B1
- Authority
- DK
- Denmark
- Prior art keywords
- mitomycin
- process according
- amino
- lower alkyl
- chloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72865085 | 1985-04-29 | ||
| US06/728,650 US4652644A (en) | 1985-04-29 | 1985-04-29 | Process for preparation of N7 -amidino substituted mitomycin C derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK193786D0 DK193786D0 (da) | 1986-04-28 |
| DK193786A DK193786A (da) | 1986-10-30 |
| DK168708B1 true DK168708B1 (da) | 1994-05-24 |
Family
ID=24927725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK193786A DK168708B1 (da) | 1985-04-29 | 1986-04-28 | Fremgangsmåde til fremstilling af N7-amidinosubstituerede mitomycin C-derivater |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4652644A (it) |
| KR (1) | KR910002080B1 (it) |
| CN (1) | CN1020731C (it) |
| AR (1) | AR242210A1 (it) |
| AT (1) | AT394724B (it) |
| CA (1) | CA1247617A (it) |
| CS (1) | CS271331B2 (it) |
| DD (1) | DD258011A5 (it) |
| DK (1) | DK168708B1 (it) |
| ES (1) | ES8706685A1 (it) |
| FI (1) | FI83519C (it) |
| GR (1) | GR861152B (it) |
| HU (1) | HU194243B (it) |
| IT (1) | IT1208605B (it) |
| LU (1) | LU86411A1 (it) |
| NO (1) | NO164543C (it) |
| OA (1) | OA08243A (it) |
| PT (1) | PT82471B (it) |
| SU (1) | SU1436881A3 (it) |
| YU (1) | YU45778B (it) |
| ZW (1) | ZW5386A1 (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6354380A (ja) * | 1986-08-26 | 1988-03-08 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
| JPH0867676A (ja) * | 1994-03-30 | 1996-03-12 | Eisai Kagaku Kk | 保護アミノチアゾリル酢酸誘導体 |
| JP3202960B2 (ja) * | 1998-02-17 | 2001-08-27 | 大塚化学株式会社 | ハロゲン化剤及び水酸基のハロゲン化方法 |
| CN104710426B (zh) * | 2014-12-12 | 2017-08-01 | 常州大学 | 苯并吡咯里西啶生物碱及其制备方法和用途 |
| CN104478885B (zh) * | 2014-12-12 | 2017-08-01 | 常州大学 | 9‑氨基‑9a‑烯丙基苯并吡咯里西啶生物碱的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1135270B (it) * | 1980-04-12 | 1986-08-20 | Erba Farmitalia | 3-amidino-ansamicine |
| US4487769A (en) * | 1982-06-04 | 1984-12-11 | Bristol-Myers Company | Amidines |
| US4567256A (en) * | 1983-05-09 | 1986-01-28 | Bristol-Myers Company | Amidine process |
-
1985
- 1985-04-29 US US06/728,650 patent/US4652644A/en not_active Expired - Fee Related
-
1986
- 1986-02-11 CA CA000501609A patent/CA1247617A/en not_active Expired
- 1986-02-28 KR KR1019860001449A patent/KR910002080B1/ko not_active IP Right Cessation
- 1986-03-04 ZW ZW53/86A patent/ZW5386A1/xx unknown
- 1986-03-13 AR AR86303372A patent/AR242210A1/es active
- 1986-03-13 CN CN86101611A patent/CN1020731C/zh not_active Expired - Fee Related
- 1986-04-17 AT AT0101886A patent/AT394724B/de not_active IP Right Cessation
- 1986-04-24 FI FI861720A patent/FI83519C/fi not_active IP Right Cessation
- 1986-04-25 OA OA58844A patent/OA08243A/xx unknown
- 1986-04-28 DD DD86289675A patent/DD258011A5/de not_active IP Right Cessation
- 1986-04-28 SU SU864027308A patent/SU1436881A3/ru active
- 1986-04-28 NO NO861652A patent/NO164543C/no unknown
- 1986-04-28 DK DK193786A patent/DK168708B1/da not_active IP Right Cessation
- 1986-04-28 PT PT82471A patent/PT82471B/pt not_active IP Right Cessation
- 1986-04-28 ES ES554469A patent/ES8706685A1/es not_active Expired
- 1986-04-28 IT IT8620228A patent/IT1208605B/it active
- 1986-04-28 LU LU86411A patent/LU86411A1/fr unknown
- 1986-04-29 YU YU70086A patent/YU45778B/sh unknown
- 1986-04-29 GR GR861152A patent/GR861152B/el unknown
- 1986-04-29 HU HU861783A patent/HU194243B/hu not_active IP Right Cessation
- 1986-04-29 CS CS863117A patent/CS271331B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DD258011A5 (de) | 1988-07-06 |
| IT8620228A0 (it) | 1986-04-28 |
| DK193786D0 (da) | 1986-04-28 |
| SU1436881A3 (ru) | 1988-11-07 |
| YU45778B (sh) | 1992-07-20 |
| NO861652L (no) | 1986-10-30 |
| HUT40665A (en) | 1987-01-28 |
| CA1247617A (en) | 1988-12-28 |
| PT82471B (pt) | 1988-10-14 |
| DK193786A (da) | 1986-10-30 |
| FI83519B (fi) | 1991-04-15 |
| ES554469A0 (es) | 1987-07-01 |
| CN86101611A (zh) | 1986-12-17 |
| CS311786A2 (en) | 1989-12-13 |
| KR910002080B1 (ko) | 1991-04-03 |
| ZW5386A1 (en) | 1986-10-01 |
| LU86411A1 (fr) | 1986-11-05 |
| PT82471A (en) | 1986-05-01 |
| HU194243B (en) | 1988-01-28 |
| NO164543B (no) | 1990-07-09 |
| OA08243A (fr) | 1987-10-30 |
| AT394724B (de) | 1992-06-10 |
| CS271331B2 (en) | 1990-09-12 |
| KR860008201A (ko) | 1986-11-12 |
| CN1020731C (zh) | 1993-05-19 |
| ATA101886A (de) | 1991-11-15 |
| AR242210A1 (es) | 1993-03-31 |
| NO164543C (no) | 1990-10-17 |
| GR861152B (en) | 1986-09-02 |
| FI861720A (fi) | 1986-10-30 |
| ES8706685A1 (es) | 1987-07-01 |
| YU70086A (en) | 1987-12-31 |
| FI83519C (fi) | 1991-07-25 |
| IT1208605B (it) | 1989-07-10 |
| FI861720A0 (fi) | 1986-04-24 |
| US4652644A (en) | 1987-03-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |