DK168421B1 - Farmaceutiske præparater af 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]-indol-1-eddikesyre eller salte deraf - Google Patents

Farmaceutiske præparater af 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]-indol-1-eddikesyre eller salte deraf Download PDF

Info

Publication number
DK168421B1
DK168421B1 DK531088A DK531088A DK168421B1 DK 168421 B1 DK168421 B1 DK 168421B1 DK 531088 A DK531088 A DK 531088A DK 531088 A DK531088 A DK 531088A DK 168421 B1 DK168421 B1 DK 168421B1
Authority
DK
Denmark
Prior art keywords
weight
etodolac
base material
release
tablet
Prior art date
Application number
DK531088A
Other languages
Danish (da)
English (en)
Other versions
DK531088D0 (da
DK531088A (da
Inventor
John Joseph Michelucci
Deborah Marie Sherman
Richard Jay Denale
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of DK531088D0 publication Critical patent/DK531088D0/da
Publication of DK531088A publication Critical patent/DK531088A/da
Application granted granted Critical
Publication of DK168421B1 publication Critical patent/DK168421B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
  • Ceramic Products (AREA)
DK531088A 1987-09-24 1988-09-23 Farmaceutiske præparater af 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]-indol-1-eddikesyre eller salte deraf DK168421B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10050187A 1987-09-24 1987-09-24
US10050187 1987-09-24

Publications (3)

Publication Number Publication Date
DK531088D0 DK531088D0 (da) 1988-09-23
DK531088A DK531088A (da) 1989-03-25
DK168421B1 true DK168421B1 (da) 1994-03-28

Family

ID=22280080

Family Applications (1)

Application Number Title Priority Date Filing Date
DK531088A DK168421B1 (da) 1987-09-24 1988-09-23 Farmaceutiske præparater af 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]-indol-1-eddikesyre eller salte deraf

Country Status (21)

Country Link
US (1) US4966768A (de)
EP (1) EP0309157B1 (de)
JP (1) JP2879061B2 (de)
KR (1) KR960009410B1 (de)
AT (1) ATE62132T1 (de)
AU (1) AU613663B2 (de)
CA (1) CA1318600C (de)
DE (1) DE3862272D1 (de)
DK (1) DK168421B1 (de)
ES (1) ES2021838B3 (de)
FI (1) FI89005C (de)
GB (1) GB2209940B (de)
GR (1) GR3001739T3 (de)
HK (1) HK41994A (de)
HU (1) HU200920B (de)
IE (1) IE60311B1 (de)
IL (1) IL87757A (de)
MX (1) MX171463B (de)
PH (1) PH26146A (de)
PT (1) PT88564B (de)
ZA (1) ZA887162B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017673A1 (en) * 1992-03-03 1993-09-16 Top Gold Pty., Limited Sustained release analgesics
US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US5419917A (en) * 1994-02-14 1995-05-30 Andrx Pharmaceuticals, Inc. Controlled release hydrogel formulation
SK74396A3 (en) * 1995-06-13 1997-04-09 American Home Prod Organoleptically acceptable oral pharmaceutical compositions
US6274171B1 (en) 1996-03-25 2001-08-14 American Home Products Corporation Extended release formulation of venlafaxine hydrochloride
US20030215507A1 (en) * 1996-03-25 2003-11-20 Wyeth Extended release formulation
PE57198A1 (es) 1996-03-25 1998-10-10 American Home Prod Formula de liberacion prolongada
US20060068000A1 (en) * 1996-03-25 2006-03-30 Wyeth Extended release formulation
US6251430B1 (en) 1998-02-04 2001-06-26 Guohua Zhang Water insoluble polymer based sustained release formulation
US6090411A (en) * 1998-03-09 2000-07-18 Temple University Monolithic tablet for controlled drug release
US6106862A (en) * 1998-08-13 2000-08-22 Andrx Corporation Once daily analgesic tablet
JP2002531491A (ja) 1998-12-11 2002-09-24 ノストラム・ファーマスーティカルズ・インコーポレイテッド ヒドロコロイドおよびセルロースエーテルを含む持続放出性錠剤
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US7151100B1 (en) * 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
IN190974B (de) * 1999-09-10 2003-09-06 Ranbaxy Lab Ltd
US20040152672A1 (en) * 2000-08-09 2004-08-05 Carson Dennis A. Indole compounds useful for the treatment of cancer
US20070098784A1 (en) * 2001-09-28 2007-05-03 Nutraceutix, Inc. Delivery system for biological component
CA2461708C (en) * 2001-09-28 2012-08-07 Nutraceutix, Inc. Delivery system for biological component
IL161491A0 (en) * 2001-11-07 2004-09-27 Synthon Bv Tamsulosin tablets
IL146462A (en) * 2001-11-13 2015-02-26 Lycored Bio Ltd Prolonged-release preparations containing as an active compound and analapaxin hydrochloride
EP1465607B1 (de) * 2002-01-09 2007-03-21 UCB Farchim S.A. Pharmazeutische zusammensetzung mit modifizierter freisetzung
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
WO2004026116A2 (en) * 2002-09-19 2004-04-01 The Regents Of The University Of California Use of etodoclac to treat hyperplasia
US6703044B1 (en) 2002-10-25 2004-03-09 Dexcel Pharma Tech, Ltd Venlafaxine formulations
US7018658B2 (en) * 2002-11-14 2006-03-28 Synthon Bv Pharmaceutical pellets comprising tamsulosin
US20040185097A1 (en) * 2003-01-31 2004-09-23 Glenmark Pharmaceuticals Ltd. Controlled release modifying complex and pharmaceutical compositions thereof
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US20050106253A1 (en) * 2003-11-13 2005-05-19 Platteeuw Johannes J. Pharmaceutical pellets comprising tamsulosin
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
JP5457830B2 (ja) 2006-04-03 2014-04-02 オディディ，イサ オルガノゾル被膜を含む制御放出送達デバイス
AU2007242077B2 (en) * 2006-04-26 2013-11-14 Alphapharm Pty Ltd Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2007131804A1 (en) 2006-05-17 2007-11-22 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
US8465770B2 (en) 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
TR200908308A1 (tr) 2010-01-18 2011-08-22 Turgut İlaçlari A.Ş. Etodolak içeren sürekli salım tablet formulasyonu
CN102485215B (zh) * 2010-12-03 2013-05-15 沈阳药科大学 依托度酸定时释药微丸制剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3939178A (en) * 1971-06-01 1976-02-17 American Home Products Corporation Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles
US3954959A (en) * 1973-03-28 1976-05-04 A/S Alfred Benzon Oral drug preparations
GB1468172A (en) * 1973-03-28 1977-03-23 Benzon As Alfred Oral drug preparations
US4309406A (en) * 1979-07-10 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4309405A (en) * 1979-08-09 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4309404A (en) * 1979-08-09 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4533551A (en) * 1984-02-17 1985-08-06 American Home Products Corporation Method of treating arthritis with etodolac
US4657757A (en) * 1985-03-29 1987-04-14 Schering Corporation Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate

Also Published As

Publication number Publication date
GB2209940B (en) 1991-08-14
GR3001739T3 (en) 1992-11-23
HK41994A (en) 1994-05-06
IE882709L (en) 1989-03-24
CA1318600C (en) 1993-06-01
JPH02270820A (ja) 1990-11-05
ES2021838B3 (es) 1991-11-16
IL87757A0 (en) 1989-02-28
PH26146A (en) 1992-03-18
DK531088D0 (da) 1988-09-23
JP2879061B2 (ja) 1999-04-05
IE60311B1 (en) 1994-06-29
HUT50631A (en) 1990-03-28
FI89005C (fi) 1993-08-10
EP0309157A1 (de) 1989-03-29
DE3862272D1 (de) 1991-05-08
FI884245A0 (fi) 1988-09-15
HU200920B (en) 1990-09-28
DK531088A (da) 1989-03-25
ATE62132T1 (de) 1991-04-15
IL87757A (en) 1992-06-21
AU613663B2 (en) 1991-08-08
PT88564B (pt) 1992-11-30
AU2215388A (en) 1989-05-11
PT88564A (pt) 1988-10-01
FI89005B (fi) 1993-04-30
GB2209940A (en) 1989-06-01
ZA887162B (en) 1990-05-30
FI884245A (fi) 1989-03-25
KR890004686A (ko) 1989-05-09
KR960009410B1 (en) 1996-07-19
GB8821749D0 (en) 1988-10-19
US4966768A (en) 1990-10-30
EP0309157B1 (de) 1991-04-03
MX171463B (es) 1993-10-28

Similar Documents

Publication Publication Date Title
DK168421B1 (da) Farmaceutiske præparater af 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]-indol-1-eddikesyre eller salte deraf
AU677595B2 (en) Sustained release tablets containing bupropion
US4942040A (en) Pharmaceutical preparation and a process for its preparation
JP4976011B2 (ja) 制御放出モルヒネ製剤
US20110177168A1 (en) Composition
EP0210540A1 (de) Zeitgesteuerte explodierende Systeme, sowie Verfahren zu deren Herstellung
PL185604B1 (pl) Preparat farmaceutyczny zawierający bromowodorek darifenacyny
HU197839B (en) Process for producing metoprolol containing pharmaceutical compositions
NO174795B (no) Fremgangsmåte for fremstilling av faste farmasöytiske preparater som inneholder estere og/eller etere av polyetylenglykoler som opplöseliggjörende middel
NZ337120A (en) Sustained release formulations of an erythromycin derivative and a pharmaceutically acceptable water -soluble polymer
US5968553A (en) Pharmaceutical composition containing bupropion hydrochloride and an inorganic acid stabilizer
EP1154762B1 (de) Kapseln mit loratadin und pseudoephedrin enthaltenden zusammensetzungen
EP0264989A1 (de) Perorale galenische Formulierungen von Rheinderivaten mit verzögerter Freigabe
JP3110794B2 (ja) １，４−ジヒドロピリジン誘導体を含有する製剤
CA2004177C (en) Readily absorbable drug formulation of nb-818
JPH0757726B2 (ja) 高分子量ヒドロキシプロピルメチルセルロースを基剤にした徐放性錠剤
AU615950B2 (en) Pharmaceutical composition for piperidinoalkanol derivatives
JPH0236571B2 (ja) Jizokuseiseizai
JPH0466846B2 (de)

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired