MX171463B - Sistema de dosificacion de liberacion sostenida y procedimiento para su preparacion - Google Patents
Sistema de dosificacion de liberacion sostenida y procedimiento para su preparacionInfo
- Publication number
- MX171463B MX171463B MX013091A MX1309188A MX171463B MX 171463 B MX171463 B MX 171463B MX 013091 A MX013091 A MX 013091A MX 1309188 A MX1309188 A MX 1309188A MX 171463 B MX171463 B MX 171463B
- Authority
- MX
- Mexico
- Prior art keywords
- weight percent
- dosage form
- procedure
- preparation
- sustained release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
La presente invención se refiere a forma de dosificación continua que tiene un material protador base combinado con etodolac y un modificador de la tasa de liberación, conformado y comprimido en una forma de dosificación unitaria sólida que tiene un sistema de liberación regular y prolongada al administrarse; caracterizada porque el material portador base es celulosa de hidroxipropilmetilo en mezcla con de 15 al 28 por ciento en peso de la mezcla de celulosa de etilo, en donde la celulosa de hidroxipropilmetilo tiene un contenido de hidroxipropoxilo de aproximadamente 7.0 a aproximadamente 8.6 por ciento en peso, un contenido de metoxilo de aproximadamente 19 - 24 por ciento en peso, y un peso molecular promedio menor de 50,000 el agente modificador de la tasa de liberación es una cantidad efectiva de un ácido tamponador de una sal ácida o de una mezcla de los mismos, aceptables fisiológicamente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10050187A | 1987-09-24 | 1987-09-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX171463B true MX171463B (es) | 1993-10-28 |
Family
ID=22280080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX013091A MX171463B (es) | 1987-09-24 | 1988-09-21 | Sistema de dosificacion de liberacion sostenida y procedimiento para su preparacion |
Country Status (21)
Country | Link |
---|---|
US (1) | US4966768A (es) |
EP (1) | EP0309157B1 (es) |
JP (1) | JP2879061B2 (es) |
KR (1) | KR960009410B1 (es) |
AT (1) | ATE62132T1 (es) |
AU (1) | AU613663B2 (es) |
CA (1) | CA1318600C (es) |
DE (1) | DE3862272D1 (es) |
DK (1) | DK168421B1 (es) |
ES (1) | ES2021838B3 (es) |
FI (1) | FI89005C (es) |
GB (1) | GB2209940B (es) |
GR (1) | GR3001739T3 (es) |
HK (1) | HK41994A (es) |
HU (1) | HU200920B (es) |
IE (1) | IE60311B1 (es) |
IL (1) | IL87757A (es) |
MX (1) | MX171463B (es) |
PH (1) | PH26146A (es) |
PT (1) | PT88564B (es) |
ZA (1) | ZA887162B (es) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993017673A1 (en) * | 1992-03-03 | 1993-09-16 | Top Gold Pty., Limited | Sustained release analgesics |
US5314697A (en) * | 1992-10-23 | 1994-05-24 | Schering Corporation | Stable extended release oral dosage composition comprising loratadine and pseudoephedrine |
US6676967B1 (en) | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
US5419917A (en) * | 1994-02-14 | 1995-05-30 | Andrx Pharmaceuticals, Inc. | Controlled release hydrogel formulation |
IN182040B (es) * | 1995-06-13 | 1998-12-12 | American Home Prod | |
PE57198A1 (es) | 1996-03-25 | 1998-10-10 | American Home Prod | Formula de liberacion prolongada |
US20060068001A1 (en) * | 1996-03-25 | 2006-03-30 | Wyeth | Extended release formulation |
US6274171B1 (en) | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
US20030215507A1 (en) * | 1996-03-25 | 2003-11-20 | Wyeth | Extended release formulation |
US6251430B1 (en) | 1998-02-04 | 2001-06-26 | Guohua Zhang | Water insoluble polymer based sustained release formulation |
US6090411A (en) * | 1998-03-09 | 2000-07-18 | Temple University | Monolithic tablet for controlled drug release |
US6106862A (en) * | 1998-08-13 | 2000-08-22 | Andrx Corporation | Once daily analgesic tablet |
EP1137403B1 (en) | 1998-12-11 | 2009-03-11 | Nostrum Pharmaceuticals, Inc. | Sustained release tablet containing hydrocolloid and cellulose ether |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
US7151100B1 (en) * | 1999-07-23 | 2006-12-19 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
IN190974B (es) * | 1999-09-10 | 2003-09-06 | Ranbaxy Lab Ltd | |
US20040152672A1 (en) * | 2000-08-09 | 2004-08-05 | Carson Dennis A. | Indole compounds useful for the treatment of cancer |
WO2003026687A1 (en) * | 2001-09-28 | 2003-04-03 | Nutraceutix, Inc. | Delivery system for biological component |
US20070098784A1 (en) | 2001-09-28 | 2007-05-03 | Nutraceutix, Inc. | Delivery system for biological component |
IL161491A0 (en) * | 2001-11-07 | 2004-09-27 | Synthon Bv | Tamsulosin tablets |
IL146462A (en) * | 2001-11-13 | 2015-02-26 | Lycored Bio Ltd | Prolonged-release preparations containing as an active compound and analapaxin hydrochloride |
AU2003202550A1 (en) * | 2002-01-09 | 2003-07-24 | Ucb, S.A. | Pharmaceutical formulations with modified release |
EP2316469A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
AU2003295336A1 (en) * | 2002-09-19 | 2004-04-08 | Dennis A. Carson | Use of etodoclac to treat hyperplasia |
US6703044B1 (en) | 2002-10-25 | 2004-03-09 | Dexcel Pharma Tech, Ltd | Venlafaxine formulations |
US7018658B2 (en) * | 2002-11-14 | 2006-03-28 | Synthon Bv | Pharmaceutical pellets comprising tamsulosin |
US20040185097A1 (en) * | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
US20050106253A1 (en) * | 2003-11-13 | 2005-05-19 | Platteeuw Johannes J. | Pharmaceutical pellets comprising tamsulosin |
US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
JP5457830B2 (ja) | 2006-04-03 | 2014-04-02 | オディディ,イサ | オルガノゾル被膜を含む制御放出送達デバイス |
PL2010158T3 (pl) * | 2006-04-26 | 2016-09-30 | Formulacje o kontrolowanym uwalnianiu zawierające niepowlekaną odrębną jednostkę(-i) i macierz o przedłużonym uwalnianiu | |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
WO2007131804A1 (en) | 2006-05-17 | 2007-11-22 | Synthon B.V. | Tablet composition with a prolonged release of tamsulosin |
US8465770B2 (en) | 2008-12-24 | 2013-06-18 | Synthon Bv | Low dose controlled release tablet |
TR200908308A1 (tr) | 2010-01-18 | 2011-08-22 | Turgut İlaçlari A.Ş. | Etodolak içeren sürekli salım tablet formulasyonu |
CN102485215B (zh) * | 2010-12-03 | 2013-05-15 | 沈阳药科大学 | 依托度酸定时释药微丸制剂及其制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3939178A (en) * | 1971-06-01 | 1976-02-17 | American Home Products Corporation | Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles |
GB1468172A (en) * | 1973-03-28 | 1977-03-23 | Benzon As Alfred | Oral drug preparations |
US3954959A (en) * | 1973-03-28 | 1976-05-04 | A/S Alfred Benzon | Oral drug preparations |
US4309406A (en) * | 1979-07-10 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
US4309404A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
US4309405A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
US4533551A (en) * | 1984-02-17 | 1985-08-06 | American Home Products Corporation | Method of treating arthritis with etodolac |
US4657757A (en) * | 1985-03-29 | 1987-04-14 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
-
1988
- 1988-09-07 IE IE270988A patent/IE60311B1/en not_active IP Right Cessation
- 1988-09-09 CA CA000576957A patent/CA1318600C/en not_active Expired - Lifetime
- 1988-09-13 AU AU22153/88A patent/AU613663B2/en not_active Expired
- 1988-09-15 IL IL87757A patent/IL87757A/xx active Protection Beyond IP Right Term
- 1988-09-15 FI FI884245A patent/FI89005C/fi not_active IP Right Cessation
- 1988-09-16 AT AT88308564T patent/ATE62132T1/de not_active IP Right Cessation
- 1988-09-16 DE DE8888308564T patent/DE3862272D1/de not_active Expired - Lifetime
- 1988-09-16 GB GB8821749A patent/GB2209940B/en not_active Expired - Lifetime
- 1988-09-16 ES ES88308564T patent/ES2021838B3/es not_active Expired - Lifetime
- 1988-09-16 EP EP88308564A patent/EP0309157B1/en not_active Expired - Lifetime
- 1988-09-17 JP JP63233366A patent/JP2879061B2/ja not_active Expired - Lifetime
- 1988-09-21 MX MX013091A patent/MX171463B/es unknown
- 1988-09-21 PT PT88564A patent/PT88564B/pt not_active IP Right Cessation
- 1988-09-23 ZA ZA887162A patent/ZA887162B/xx unknown
- 1988-09-23 HU HU884992A patent/HU200920B/hu unknown
- 1988-09-23 KR KR88012298A patent/KR960009410B1/ko not_active IP Right Cessation
- 1988-09-23 PH PH37584A patent/PH26146A/en unknown
- 1988-09-23 DK DK531088A patent/DK168421B1/da not_active IP Right Cessation
- 1988-11-07 US US07/268,646 patent/US4966768A/en not_active Expired - Lifetime
-
1991
- 1991-04-04 GR GR91400364T patent/GR3001739T3/el unknown
-
1994
- 1994-04-28 HK HK41994A patent/HK41994A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA887162B (en) | 1990-05-30 |
FI884245A (fi) | 1989-03-25 |
EP0309157A1 (en) | 1989-03-29 |
ES2021838B3 (es) | 1991-11-16 |
HUT50631A (en) | 1990-03-28 |
PT88564A (pt) | 1988-10-01 |
GB8821749D0 (en) | 1988-10-19 |
DE3862272D1 (de) | 1991-05-08 |
DK168421B1 (da) | 1994-03-28 |
JP2879061B2 (ja) | 1999-04-05 |
FI884245A0 (fi) | 1988-09-15 |
HU200920B (en) | 1990-09-28 |
IL87757A (en) | 1992-06-21 |
PT88564B (pt) | 1992-11-30 |
CA1318600C (en) | 1993-06-01 |
AU613663B2 (en) | 1991-08-08 |
DK531088A (da) | 1989-03-25 |
US4966768A (en) | 1990-10-30 |
IL87757A0 (en) | 1989-02-28 |
KR960009410B1 (en) | 1996-07-19 |
ATE62132T1 (de) | 1991-04-15 |
GR3001739T3 (en) | 1992-11-23 |
HK41994A (en) | 1994-05-06 |
PH26146A (en) | 1992-03-18 |
GB2209940A (en) | 1989-06-01 |
KR890004686A (ko) | 1989-05-09 |
DK531088D0 (da) | 1988-09-23 |
FI89005B (fi) | 1993-04-30 |
AU2215388A (en) | 1989-05-11 |
IE60311B1 (en) | 1994-06-29 |
FI89005C (fi) | 1993-08-10 |
EP0309157B1 (en) | 1991-04-03 |
GB2209940B (en) | 1991-08-14 |
JPH02270820A (ja) | 1990-11-05 |
IE882709L (en) | 1989-03-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX171463B (es) | Sistema de dosificacion de liberacion sostenida y procedimiento para su preparacion | |
ES8500740A1 (es) | Un metodo para la preparacion de una forma posologica unitaria solida, terapeuticamente activa, con pauta de liberacion regular y prolongada al ser administrada. | |
YU46701B (sh) | Postupak u za dobijanje osnovnog nosećeg materijala za dozne oblike lekova sa produženim izdvajanjem aktivne supstance | |
IL85523A (en) | Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it | |
SE8207167L (sv) | Metod for framstellning av terapeutiska foreningar med forlengd utlosningstid baserade pa hydroxypropylmetylcellulosa | |
ATE104545T1 (de) | Arzneistoffabgabe-zusammensetzungen. | |
GB2237510B (en) | Small particle drug compositions for nasal administration | |
GB1518843A (en) | Process for the preparation of hollow particulates | |
MY118371A (en) | Tetrahydrolipstatin containing compositions | |
IL117356A (en) | Controlled release matrix and pharmaceutical compositions for oral administration containing it | |
US3590117A (en) | Long-lasting troche containing guar gum | |
SE8303531D0 (sv) | Farmaceutisk komposition | |
IS1694B (is) | Lyfjablanda til að gefa dýrum um munn sem inniheldur prótonupumpublokkara | |
DE69931498D1 (de) | Oral zersetzbare tablette mit ausbildung eines zähen schleims | |
TR199500856A2 (tr) | Nefesle ice cekilerek alinan farmasötik bilesim. | |
UA29563C2 (uk) | Мікрокапсула для тривалого вивільнення фізіологічно активного пептиду | |
IL102848A0 (en) | Polypeptides having growth hormone releasing activity,their use and pharmaceutical compositions containing them | |
DE69233130D1 (de) | Kaubare zusammensetzung zur arzneimittelfreisetzung | |
KR850700212A (ko) | 서방성 약제학적 캼셀제 | |
NZ510563A (en) | Multiple unit controlled food effect-independent release pharmaceutical preparations and method for preparing the same | |
NZ337418A (en) | Paracetamol composition with improved rate of absorption | |
KR870700354A (ko) | 기포성 아세틸살리실산 정제의 개선 | |
ID22763A (id) | Komposisi penstabil tibolon | |
KR830002510A (ko) | 생물학적 활성화합물과 하이드록시알킬 전분으로 구성되는 조성물 | |
GB1279214A (en) | Long-acting oral carrier |