DK1667696T3 - Probiotisk opbevaring og indgivelse - Google Patents

Probiotisk opbevaring og indgivelse Download PDF

Info

Publication number
DK1667696T3
DK1667696T3 DK04761376.5T DK04761376T DK1667696T3 DK 1667696 T3 DK1667696 T3 DK 1667696T3 DK 04761376 T DK04761376 T DK 04761376T DK 1667696 T3 DK1667696 T3 DK 1667696T3
Authority
DK
Denmark
Prior art keywords
probiotic
protein
bacteria
carbohydrate
encapsulated
Prior art date
Application number
DK04761376.5T
Other languages
English (en)
Inventor
Ross Crittenden
Luz Sanguansri
Mary Ann Augustin
Original Assignee
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2003905338A external-priority patent/AU2003905338A0/en
Application filed by Commw Scient Ind Res Org filed Critical Commw Scient Ind Res Org
Application granted granted Critical
Publication of DK1667696T3 publication Critical patent/DK1667696T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/064—Saccharomycetales, e.g. baker's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medical Informatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • General Preparation And Processing Of Foods (AREA)

Claims (15)

  1. PROBIOTISK OPBEVARING OG INDGIVELSE
    1. Fremgangsmåde til indkapsling af probiotika, hvor én eller flere probiotiske mikroorganismer indkapsles i en protein- og carbohydratblanding ved dispersion a) i en vandig suspension af et protein og et carbohydrat b) i en olie-i-vandemulsion af et filmdannende protein og et carbohydrat og et fedtstof, eller c) i en olie, der efterfølgende dispergeres i et filmdannende protein og et carbohydrat
  2. 2. Fremgangsmåde ifølge krav 1, hvor carbohydratet indeholder en reducerende sukkergruppe.
  3. 3. Fremgangsmåde ifølge krav 1 eller 2 hvor ét eller flere præbiotiske materialer blandes med de probiotiske mikroorganismer.
  4. 4. Fremgangsmåde ifølge krav 1 eller 2, hvor carbohydratet i den filmdannende sammensætning er et præbiotisk carbohydrat.
  5. 5. Fremgangsmåde ifølge krav 1, hvori proteinet er casein eller valleprotein.
  6. 6. Fremgangsmåde ifølge krav 1 eller 2, hvor carbohydratet er en resistent stivelse eller en amyloserig stivelse.
  7. 7. Fremgangsmåde ifølge krav 2, hvor proteinet og carbohydratet er varmebehandlet.
  8. 8. Fremgangsmåde ifølge krav 2, hvor proteinet og carbohydratet er varmebehandlet i nærvær af en olie eller et fedtstof før tilsætning af de probiotiske bakterier.
  9. 9. Fremgangsmåde ifølge krav 3, hvor stivelsen behandles med opvarmning og/eller mikro fluidisering.
  10. 10. Fremgangsmåde ifølge krav 1, hvor den probiotiske mikroorganisme er udvalgt fra bifidobakterier, lactobacilli, saccharomyces, lactococci, streptococci og propionibakterier
  11. 11. Indkapslet probiotisk mikroorganisme, der kan opnås ved fremgangsmåden ifølge et hvilket som helst af kravene 1 til 10.
  12. 12. Indkapslet probiotisk mikroorganisme ifølge krav 11, der er frysetørret for at danne et pulver.
  13. 13. Probiotisk pulver ifølge krav 12, hvilket pulver består af en probiotisk bakterie udvalgt fra bifidobakterier, lactobacilli, saccharomyces, lactococci, streptococci og propionibakterier indkapslet i en filmdannende blanding af casein eller valleprotein og et oligosaccharid.
  14. 14. Probiotisk pulver ifølge krav 13, hvori den filmdannende blanding er opvarmet for at danne Maillard-reaktionsprodukter mellem oligosaccharidet og caseinet eller valleproteinet.
  15. 15. Probiotisk pulver ifølge krav 13, hvori de probiotiske bakterier er et flydende probiotisk koncentrat.
DK04761376.5T 2003-10-01 2004-09-30 Probiotisk opbevaring og indgivelse DK1667696T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2003905338A AU2003905338A0 (en) 2003-10-01 Probiotic Storage and Delivery
PCT/AU2004/001341 WO2005030229A1 (en) 2003-10-01 2004-09-30 Probiotic storage and delivery

Publications (1)

Publication Number Publication Date
DK1667696T3 true DK1667696T3 (da) 2016-02-29

Family

ID=34382672

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04761376.5T DK1667696T3 (da) 2003-10-01 2004-09-30 Probiotisk opbevaring og indgivelse

Country Status (10)

Country Link
US (1) US8871266B2 (da)
EP (1) EP1667696B1 (da)
JP (4) JP2007507209A (da)
KR (2) KR20060092231A (da)
CN (1) CN1859920B (da)
CA (1) CA2538676C (da)
DK (1) DK1667696T3 (da)
ES (1) ES2561831T3 (da)
NZ (1) NZ545925A (da)
WO (1) WO2005030229A1 (da)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8871266B2 (en) * 2003-10-01 2014-10-28 Commonwealth Scientific & Industrial Research Organisation Probiotic storage and delivery
EP1684733B1 (en) * 2003-11-21 2011-09-21 Commonwealth Scientific And Industrial Research Organisation G i tract delivery systems
AU2005224162A1 (en) * 2004-03-19 2005-09-29 Danisco A/S Emulsifier composition for shortening
WO2005105851A1 (en) * 2004-04-28 2005-11-10 Commonwealth Scientific & Industrial Research Organisation Starch treatment process
US7318920B2 (en) 2004-09-27 2008-01-15 Ez-Med Company Low water activity nutritional product having beneficial microbial and high oil content
GB0503684D0 (en) * 2005-02-23 2005-03-30 Ici Plc Emulsifiers and emulsions
US8968721B2 (en) 2005-12-28 2015-03-03 Advanced Bionutrition Corporation Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
JP5214464B2 (ja) 2005-12-28 2013-06-19 アドバンスド バイオニュートリション コーポレーション 多糖類、糖類およびポリオール類の乾燥マトリックスを含む、ガラス形態の、プロバイオティクス細菌用送達媒体およびその製造方法
EP2004201B1 (en) * 2006-03-29 2018-08-08 Nestec S.A. Dietary supplements containing probiotics
US8221809B2 (en) 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
PL2034973T5 (pl) 2006-06-22 2023-02-20 Dsm Ip Assets B.V. Kapsułkowane kompozycje nietrwałych związków i sposoby ich wytwarzania
WO2008001676A1 (fr) * 2006-06-26 2008-01-03 The Food Science Institute Foundation Bactérie d'acide lactique utilisée pour améliorer l'intolérance au lactose
WO2008076975A1 (en) 2006-12-18 2008-06-26 Advanced Bionutrition Corporation A dry food product containing live probiotic
WO2008088008A1 (ja) * 2007-01-17 2008-07-24 Meiji Dairies Corporation 消化管機能異常症予防及び／又は治療剤
NZ555022A (en) * 2007-11-07 2010-09-30 Encoate Holdings Ltd Stabilisation of dried biological material with oil and biopolymer
IL199781A0 (en) 2009-07-09 2010-05-17 Yohai Zorea Heat resistant probiotic compositions and healthy food comprising them
US20110020519A1 (en) * 2008-01-04 2011-01-27 Aveka, Inc. Encapsulation of oxidatively unstable compounds
US20110059164A1 (en) * 2008-01-04 2011-03-10 Aveka, Inc. Encapsulation of oxidatively unstable compounds
KR100930427B1 (ko) * 2008-01-25 2009-12-08 정명준 3중 코팅 유산균의 제조방법 및 나노 입자 코팅 방법, 그방법으로 제조된 3중 코팅 유산균 및 이를 포함하는 제품
JP5487379B2 (ja) * 2008-03-19 2014-05-07 森下仁丹株式会社 血中リン濃度上昇抑制剤
CN101595976B (zh) * 2008-06-04 2012-09-26 东北农业大学 乳清蛋白冷凝胶包理保护双歧杆菌的方法
KR101727331B1 (ko) * 2008-08-04 2017-04-14 디에스엠 아이피 어셋츠 비.브이. 프로바이오틱 미생물을 포함하는 비드렛의 제조 방법
CA2986751A1 (en) 2009-03-27 2010-09-30 Intervet International B.V. Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish
JP5841527B2 (ja) * 2009-05-26 2016-01-13 アドバンスド バイオニュートリション コーポレーション 生物学的に活性な微生物および／または生物活性材料を含む安定な乾燥粉末組成物およびその製造方法
CA2774963A1 (en) 2009-10-09 2011-04-14 Prothera, Inc. Compositions and methods comprising pediococcus for reducing at least one symptom associated with autism spectrum disease in a person diagnosed with an autism spectrum disease
US20110123677A1 (en) * 2009-11-25 2011-05-26 Pepsico, Inc. High acid beverage products and methods to extend probiotic stability
DE102009059320A1 (de) * 2009-12-23 2011-06-30 Cofresco Frischhalteprodukte GmbH & Co. KG, 32427 Substrat mit antimikrobieller Beschichtung, ein antimikrobielles Verpackungsmaterial, sowie Verfahren zur Herstellung derselben
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
CN102725393B (zh) 2010-01-28 2015-12-02 先进生物营养公司 包含生物活性材料的干燥玻璃质组合物
SG187250A1 (en) 2010-08-13 2013-03-28 Advanced Bionutrition Corp Dry storage stabilizing composition for biological materials
EP2449887B1 (en) * 2010-11-05 2016-01-06 Nestec S.A. Method for preparing pet food containing probiotic micro-organisms
ITMI20110791A1 (it) 2011-05-09 2012-11-10 Probiotical Spa Ceppi di batteri in grado di metabolizzare gli ossalati.
ITMI20110793A1 (it) 2011-05-09 2012-11-10 Probiotical Spa Ceppi di batteri probiotici e composizione sinbiotica contenente gli stessi destinata alla alimentazione dei neonati.
ITMI20110792A1 (it) 2011-05-09 2012-11-10 Probiotical Spa Ceppi di batteri appartenenti al genere bifidobacterium per uso nel trattamento della ipercolesterolemia.
US9579353B2 (en) 2011-06-10 2017-02-28 Prothera, Inc. Pharmaceutical compositions containing pediococcus and methods for reducing the symptoms of gastroenterological syndromes
ITRM20110477A1 (it) * 2011-09-09 2013-03-10 Giovanni Mogna Composizione comprendente n-acetilcisteina e/o lisozima microincapsulato gastroprotetto in associazione con batteri probiotici in grado di ripristinare l'effetto barriera proprio dello stomaco che viene perso durante il trattamento farmacologico dell
ITMI20111718A1 (it) 2011-09-23 2013-03-24 Probiotical Spa Un materiale impermeabile alla umidita e allo ossigeno per confezionare prodotti dietetici, cosmetici e specialita medicinali.
EP2578088A1 (en) 2011-10-06 2013-04-10 Nestec S.A. Edible web comprising microorganisms
JP6229188B2 (ja) * 2012-03-23 2017-11-15 アドバンスド バイオニュートリション コープ． 生体材料のための安定化組成物
BR112015000041B1 (pt) 2012-07-05 2020-11-03 Centro Nacional De Tecnología Y Seguridad Alimentaria, Laboratorio Del Ebro micropartícula, método para a obtenção da mesma, composição, produto alimentar, farmacêutico, cosmecêutico ou nutracêutico e uso de uma micropartícula, composição ou produto
CN104968780A (zh) 2012-09-20 2015-10-07 普洛特拉有限公司 用于治疗肥胖和肥胖相关病症的益生菌组合物和方法
US10064829B2 (en) * 2013-04-19 2018-09-04 DeGama Smart, Ltd. Probiotic liquid food products for infants
ITMI20130793A1 (it) 2013-05-14 2014-11-15 Probiotical Spa Composizione comprendente batteri lattici per uso nel trattamento preventivo e/o curativo delle cistiti ricorrenti.
PL225613B1 (pl) * 2013-10-08 2017-04-28 Zachodniopomorski Univ Tech W Szczecinie Sposób wytwarzania prozdrowotnego produktu spożywczego
PL225614B1 (pl) * 2013-10-08 2017-04-28 Zachodniopomorski Univ Tech W Szczecinie Prozdrowotny produkt spożywczy
JP6306170B2 (ja) * 2014-05-24 2018-04-04 アテリオ・バイオ株式会社 難消化性物質及びその製造方法
CN104531664B (zh) * 2014-12-26 2018-08-03 四川高福记生物科技有限公司 一种以美拉德产物为壁材包埋乳酸菌的方法
CN104543611A (zh) * 2015-01-09 2015-04-29 东北农业大学 乳清蛋白与还原性低聚糖美拉德产物作为微胶囊壁材及包埋益生菌的应用
EP3280400A4 (en) 2015-04-07 2018-10-10 Her Majesty The Queen in Right of Canada, as Represented by the Minister of Agriculture and Agri-Food Method for preparing microencapsulated heat-sensitive bioactive material
CN104757138B (zh) * 2015-04-28 2017-09-19 东北农业大学 一种以益生元和乳清浓缩蛋白为壁材的微胶囊化乳清蛋白水解物的制备及其方法
DK3328215T3 (da) 2015-07-29 2021-09-13 Advanced Bionutrition Corp Stabilt tørre probiotiske sammensætninger til særlige kostanvendelser
CA3005048C (en) 2015-12-04 2023-03-28 Advanced Bionutrition Corp. Stable dry compositions having no or little sugars
CN105707897A (zh) * 2016-02-02 2016-06-29 上海交大昂立股份有限公司 一种益生菌脂性混悬液滴剂及其制备方法
US11019838B2 (en) 2017-02-21 2021-06-01 Jarrow Formulas, Inc. Probiotic dietary supplement formulation
AU2018273928B2 (en) * 2017-05-26 2023-08-10 Dakota Biotech, Llc Stabilized compositions for the controlled delivery of probiotics and methods of production thereof
WO2019118984A2 (en) 2017-12-15 2019-06-20 Solarea Bio, Inc. Microbial compositions and methods for treating type 2 diabetes, obesity, and metabolic syndrome
EP3524051A1 (en) * 2018-02-12 2019-08-14 DuPont Nutrition Biosciences ApS Matricial microencapsulation compositions
CA3092354A1 (en) * 2018-03-15 2019-09-19 University Of Southern California Fasting-mimicking diet (fmd) but not water-only fasting promotes reversal of inflammation and ibd pathology
US11980647B2 (en) 2018-09-05 2024-05-14 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
EP3846830A4 (en) 2018-09-05 2022-07-06 Solarea Bio, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MUSCULOSKELETAL DISEASES
KR102171287B1 (ko) 2018-09-18 2020-10-28 서울대학교 산학협력단 장내 프로바이오틱스 전달용 조성물 및 이의 제조방법
CO2019011687A1 (es) 2019-10-22 2020-07-31 Alpina Productos Alimenticios S A Microcápsula de probióticos
US11426353B2 (en) 2020-06-24 2022-08-30 13400719 Canada Inc. Composite coating for an active agent
FR3124953A1 (fr) * 2021-07-07 2023-01-13 Universite Clermont Auvergne Forme galénique à base de pulpe de baobab, procédés de préparation et utilisations
CN113499325B (zh) * 2021-07-08 2022-12-20 成都邦家乐君生物科技有限公司 一种用于益生菌活性保护的生物质基包封材料及包封方法
WO2023092150A1 (en) 2021-11-22 2023-05-25 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
US20230190834A1 (en) 2021-12-21 2023-06-22 Solarea Bio, Inc. Immunomodulatory compositions comprising microbial entities
KR20230114621A (ko) * 2022-01-25 2023-08-01 코스맥스 주식회사 스트렙토코커스 인판티스 균주의 추출물을 포함하는 캡슐, 및 이를 이용한 섬유, 침구류 및 의류
CN117322631B (zh) * 2023-10-31 2024-05-03 广东一源宝生物科技有限公司 调节肠道的益生菌组合物及其制备方法
CN117737182A (zh) * 2023-12-20 2024-03-22 善恩康生物科技（苏州）有限公司 一种包埋型益生菌产品的活菌数量检测方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0649654B2 (ja) 1988-11-24 1994-06-29 日本油脂株式会社 高安定性腸内有用細菌製剤及びその製造方法
JPH0482827A (ja) 1990-07-23 1992-03-16 Snow Brand Milk Prod Co Ltd 腸溶性カプセル
JP3102990B2 (ja) 1993-07-08 2000-10-23 森下仁丹株式会社 カプセルの製造方法およびそれから得られたカプセル
AUPM823094A0 (en) * 1994-09-16 1994-10-13 Goodman Fielder Limited Probiotic compositions
EP0904784A1 (en) 1997-09-22 1999-03-31 N.V. Nutricia Probiotic nutritional preparation
WO1999017788A1 (en) 1997-10-06 1999-04-15 Abbott Laboratories Composition of treatment of candidiasis
EP1065936B1 (en) 1998-03-23 2009-08-05 General Mills, Inc. Encapsulation of components into edible products
FI104405B (fi) * 1998-03-27 2000-01-31 Valtion Teknillinen Mikro-organismeja sisältävät tärkkelyskapselit ja niiden valmistusmenetelmä
JP2000063289A (ja) 1998-08-20 2000-02-29 Morinaga Milk Ind Co Ltd 生理活性物質含有製剤
US6500463B1 (en) 1999-10-01 2002-12-31 General Mills, Inc. Encapsulation of sensitive components into a matrix to obtain discrete shelf-stable particles
US7115297B2 (en) * 2000-02-22 2006-10-03 Suzanne Jaffe Stillman Nutritionally fortified liquid composition with added value delivery systems/elements/additives
PH12001000675B1 (en) * 2000-04-04 2009-09-22 Australian Food Ind Sci Ct Encapsulation of food ingredients
JP3363438B2 (ja) * 2000-05-02 2003-01-08 ビオフェルミン製薬株式会社 噴霧乾燥による菌体乾燥物
AU2001256610A1 (en) 2000-05-12 2001-11-20 Alimentary Health Limited A probiotic adhesin product, derived from lactobacillus
US20020044988A1 (en) * 2000-08-22 2002-04-18 Fuchs Eileen C. Nutritional composition and method for improving protein deposition
US6887493B2 (en) * 2000-10-25 2005-05-03 Adi Shefer Multi component controlled release system for oral care, food products, nutraceutical, and beverages
EP1213347A1 (en) 2000-11-24 2002-06-12 TDI Tournois Dynamic Innovations B.V. A method for preserving cells by processing the same into dry products
PE20030283A1 (es) 2001-07-26 2003-05-01 Alimentary Health Ltd Cepas de lactobacillus casei
US20030092163A1 (en) 2001-07-26 2003-05-15 Collins John Kevin Probiotic bifidobacterium strains
KR100979877B1 (ko) 2001-09-28 2010-09-02 뉴트라슈틱스 인코포레이티드 생물학적 성분의 전달 시스템
EP1319410A1 (en) * 2001-12-11 2003-06-18 Société des Produits Nestlé S.A. Use of micro-organisms for a directed delivery of substances to specific parts of the gut
EP1344458A1 (en) 2002-03-12 2003-09-17 Société des Produits Nestlé S.A. Probiotic delivery system
US8871266B2 (en) * 2003-10-01 2014-10-28 Commonwealth Scientific & Industrial Research Organisation Probiotic storage and delivery

Also Published As

Publication number Publication date
JP2007507209A (ja) 2007-03-29
JP6033998B2 (ja) 2016-11-30
CA2538676C (en) 2015-07-07
WO2005030229A1 (en) 2005-04-07
CA2538676A1 (en) 2005-04-07
KR20060092231A (ko) 2006-08-22
ES2561831T3 (es) 2016-03-01
EP1667696A1 (en) 2006-06-14
CN1859920A (zh) 2006-11-08
NZ545925A (en) 2008-06-30
US8871266B2 (en) 2014-10-28
JP2014140369A (ja) 2014-08-07
JP2010187670A (ja) 2010-09-02
KR20120025005A (ko) 2012-03-14
JP2016052323A (ja) 2016-04-14
KR101370143B1 (ko) 2014-03-04
EP1667696B1 (en) 2015-11-18
CN1859920B (zh) 2010-04-14
EP1667696A4 (en) 2009-09-02
US20070122397A1 (en) 2007-05-31

Similar Documents

Publication Publication Date Title
DK1667696T3 (da) Probiotisk opbevaring og indgivelse
Dianawati et al. Survival of microencapsulated probiotic bacteria after processing and during storage: a review
Solanki et al. Development of microencapsulation delivery system for long‐term preservation of probiotics as biotherapeutics agent
Anal et al. Recent advances in microencapsulation of probiotics for industrial applications and targeted delivery
JP6240386B2 (ja) プロバイオティクスの安定化
Khan et al. Development of extrusion-based legume protein isolate–alginate capsules for the protection and delivery of the acid sensitive probiotic, Bifidobacterium adolescentis
Ozyurt et al. Properties of probiotics and encapsulated probiotics in food
CA2825473C (en) Protection of microbial cells from acidic degradation
US6841181B2 (en) Encapsulated multifunctional biologically active food component, process for its production and its use
Huang et al. Microencapsulation of probiotic lactobacilli with shellac as moisture barrier and to allow controlled release
AU2012210575A1 (en) Protection of microbial cells from acidic degradation
MX2011001428A (es) Produccion de perlas microencapsuladas que comprenden compuestos probioticos.
US20240115509A1 (en) A probiotic granule having a unified stabilizing coating and a method for the production thereof
AU2004275438B2 (en) Probiotic storage and delivery
Hassan et al. Simulated Gastrointestinal System to Assess the Probiotic Properties Modified to Encapsulation of Probiotics and Their Survival Under Simulated Gastrointestinal System
Poddar et al. 17 Stabilization of Probiotics for Industrial Application
Shaharuddin et al. Encapsulation Process for Probiotic Survival during Processing
BR102020014450A2 (pt) Microcápsula simbiótica de liberação controlada e alta resistência térmica
Mandal et al. Diversification of probiotics through encapsulation technology
Thantsha Cell immobilization techniques for the preservation of probiotics
Champagne K. Kailasapathy, University of Western Sydney, Australia