DK163690A - Virksom rekombinant fremstillet syntetisk proteinpolymer - Google Patents

Virksom rekombinant fremstillet syntetisk proteinpolymer Download PDF

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Publication number
DK163690A
DK163690A DK163690A DK163690A DK163690A DK 163690 A DK163690 A DK 163690A DK 163690 A DK163690 A DK 163690A DK 163690 A DK163690 A DK 163690A DK 163690 A DK163690 A DK 163690A
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Prior art keywords
strands
synthetic protein
protein polymer
effective recombinant
manufactured synthetic
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Application number
DK163690A
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English (en)
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DK163690D0 (da
Inventor
Joseph Capello
Franco A Ferrari
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Syntro Corp
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Application filed by Syntro Corp filed Critical Syntro Corp
Publication of DK163690D0 publication Critical patent/DK163690D0/da
Publication of DK163690A publication Critical patent/DK163690A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43586Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from silkworms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/33Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Insects & Arthropods (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyamides (AREA)
DK163690A 1988-11-09 1990-07-06 Virksom rekombinant fremstillet syntetisk proteinpolymer DK163690A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26942988A 1988-11-09 1988-11-09
PCT/US1989/005016 WO1990005177A1 (en) 1988-11-09 1989-11-07 Functional recombinantly prepared synthetic protein polymer

Publications (2)

Publication Number Publication Date
DK163690D0 DK163690D0 (da) 1990-07-06
DK163690A true DK163690A (da) 1990-09-07

Family

ID=23027205

Family Applications (1)

Application Number Title Priority Date Filing Date
DK163690A DK163690A (da) 1988-11-09 1990-07-06 Virksom rekombinant fremstillet syntetisk proteinpolymer

Country Status (10)

Country Link
EP (1) EP0406357B1 (da)
JP (1) JP3338441B2 (da)
KR (1) KR0176966B1 (da)
AT (1) ATE161879T1 (da)
AU (1) AU630643B2 (da)
DE (1) DE68928532T2 (da)
DK (1) DK163690A (da)
FI (1) FI101706B (da)
NO (1) NO178625C (da)
WO (1) WO1990005177A1 (da)

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US5830713A (en) * 1986-11-04 1998-11-03 Protein Polymer Technologies, Inc. Methods for preparing synthetic repetitive DNA
US5773249A (en) * 1986-11-04 1998-06-30 Protein Polymer Technologies, Inc. High molecular weight collagen-like protein polymers
US5496712A (en) * 1990-11-06 1996-03-05 Protein Polymer High molecular weight collagen-like protein polymers
US5606019A (en) * 1987-10-29 1997-02-25 Protien Polymer Technologies, Inc. Synthetic protein as implantables
US5171505A (en) * 1990-11-28 1992-12-15 E. I. Du Pont De Nemours And Company Process for spinning polypeptide fibers
DE69131381T2 (de) * 1990-11-28 2000-01-13 Du Pont Strukturproteine durch künstliche gene
JP2745351B2 (ja) * 1991-02-14 1998-04-28 富士写真フイルム株式会社 ペプチド誘導体及びその用途
AU3130793A (en) * 1991-11-12 1993-06-15 E.I. Du Pont De Nemours And Company Collagen-like polypeptides
ATE258981T1 (de) * 1991-11-12 2004-02-15 Protein Polymer Tech Inc Kollagenartige proteinpolymere mit hohen molekularmassen
FR2685347A1 (fr) * 1991-12-23 1993-06-25 Univ Pasteur Procede biotechnologique d'obtention et de production microbienne d'oligomeres peptidiques comme substituts de la gelatine.
US5773577A (en) * 1994-03-03 1998-06-30 Protein Polymer Technologies Products comprising substrates capable of enzymatic cross-linking
US5760004A (en) * 1994-11-21 1998-06-02 Protein Polymer Technologies, Inc. Chemical modification of repetitive polymers to enhance water solubility
US5710252A (en) * 1995-02-03 1998-01-20 Eastman Kodak Company Method for recombinant yeast expression and isolation of water-soluble collagen-type polypeptides
US5670616A (en) * 1995-02-03 1997-09-23 Eastman Kodak Company Collagen-like polypeptides and biopolymers and nucleic acids encoding same
FR2738841B1 (fr) * 1995-09-15 1997-11-21 Centre Nat Rech Scient Procede de polymerisation de sequences d'acides nucleiques et ses applications
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
JP2001505539A (ja) * 1996-08-07 2001-04-24 プロテイン・スペシャルティーズ,リミテッド エラスチン及び他の線維状タンパク質由来の自己整列ペプチド
EP1124590B1 (en) * 1997-04-03 2009-06-17 California Institute Of Technology Enzyme-mediated modification of fibrin for tissue engineering
GB9718463D0 (en) * 1997-08-29 1997-11-05 Dynal As Biomolecules
US6150081A (en) 1997-12-24 2000-11-21 Fuji Photo Film B.V. Silver halide emulsions with recombinant collagen suitable for photographic application and also the preparation thereof
NL1007908C2 (nl) * 1997-12-24 1999-06-25 Fuji Photo Film Bv Zilverhalide-emulsies met recombinant collageen die geschikt zijn voor fotografische toediening alsmede de bereiding daarvan.
US7241730B2 (en) 1998-08-27 2007-07-10 Universitat Zurich Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides
US7601685B2 (en) 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
US7714020B2 (en) 2001-05-24 2010-05-11 Neuren Pharmaceuticals Limited Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate
US7605177B2 (en) 2001-05-24 2009-10-20 Neuren Pharmaceuticals Limited Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration
ATE435852T1 (de) 2001-05-24 2009-07-15 Neuren Pharmaceuticals Ltd Gpe-analoga und peptidomimetika
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
JP4504624B2 (ja) * 2002-01-17 2010-07-14 三洋化成工業株式会社 細胞接着性ペプチド含有基材
JP4705319B2 (ja) * 2002-07-19 2011-06-22 三洋化成工業株式会社 創傷被覆材
JP4510512B2 (ja) * 2003-05-21 2010-07-28 三洋化成工業株式会社 細胞接着性ポリペプチド
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (en) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
WO2007108205A1 (ja) 2006-03-17 2007-09-27 Sanyo Chemical Industries, Ltd. 細胞培養用担体
US8192760B2 (en) * 2006-12-04 2012-06-05 Abbott Cardiovascular Systems Inc. Methods and compositions for treating tissue using silk proteins
ATE554103T1 (de) * 2007-02-21 2012-05-15 Fujifilm Mfg Europe Bv Rgd-haltige rekombinante gelatine
ATE543520T1 (de) 2007-04-13 2012-02-15 Kuros Biosurgery Ag Polymergewebeversiegelung
WO2008133196A1 (ja) * 2007-04-19 2008-11-06 Fujifilm Corporation 再生医療用材料
EP2155233A2 (en) 2007-05-10 2010-02-24 Elastin Specialties, Inc. Synthetic peptide materials for joint reconstruction, repair and cushioning
JP2012512812A (ja) 2007-12-28 2012-06-07 クロス・バイオサージェリー・アクチェンゲゼルシャフト フィブリンフォームに組込まれたpdgf融合タンパク質
JP5881611B2 (ja) 2010-11-04 2016-03-09 三洋化成工業株式会社 生体組織用細胞接着性材料
EP2676683B1 (en) 2011-02-18 2016-09-21 Kyoto University Aqueous protein solution containing a material for tissue regeneration
WO2012123028A1 (en) 2011-03-16 2012-09-20 Kuros Biosurgery Ag Pharmaceutical formulation for use in spinal fusion
EP2767547B1 (en) 2011-10-12 2017-09-20 Sanyo Chemical Industries, Ltd. Proteinaceous protease inhibitor and protein solution and detergent composition containing it
JP6077316B2 (ja) * 2012-02-02 2017-02-08 三洋化成工業株式会社 組織再生用材料及び組織再生用タンパク質溶液
JP6383721B2 (ja) 2013-02-22 2018-08-29 三洋化成工業株式会社 創傷治癒剤
CN112292157A (zh) 2018-06-12 2021-01-29 国立大学法人京都大学 细胞移植用组合物和细胞移植方法
CN112789063B (zh) 2018-10-05 2022-10-25 国立大学法人广岛大学 半月板再生用材料
CN113943345B (zh) * 2021-10-14 2023-05-26 国科温州研究院(温州生物材料与工程研究所) 一种肝素中和肽、肝素中和剂及其应用

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JPS60229592A (ja) * 1984-04-27 1985-11-14 Mitsubishi Electric Corp 符号化伝送方式文字放送受信装置
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ATE233273T1 (de) * 1986-11-04 2003-03-15 Protein Polymer Tech Inc Herstellung synthetischer dns und deren verwendung bei der synthese grosser polypeptide

Also Published As

Publication number Publication date
EP0406357A4 (en) 1992-04-15
NO178625C (no) 1996-05-02
NO903025L (no) 1990-09-04
DK163690D0 (da) 1990-07-06
NO903025D0 (no) 1990-07-06
NO178625B (no) 1996-01-22
ATE161879T1 (de) 1998-01-15
WO1990005177A1 (en) 1990-05-17
DE68928532D1 (de) 1998-02-12
FI101706B1 (fi) 1998-08-14
KR900702026A (ko) 1990-12-05
EP0406357B1 (en) 1998-01-07
DE68928532T2 (de) 1998-05-28
FI101706B (fi) 1998-08-14
AU4642589A (en) 1990-05-28
EP0406357A1 (en) 1991-01-09
AU630643B2 (en) 1992-11-05
JPH03502935A (ja) 1991-07-04
KR0176966B1 (ko) 1999-04-01
JP3338441B2 (ja) 2002-10-28
FI903201A0 (fi) 1990-06-26

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