DK160269C - Analogifremgangsmaade til fremstilling af 4-aroyl-1,3-dihydro-2h-imidazol-2-oner eller et farmaceutisk acceptabelt metalsalt eller basisk ammoniumsalt deraf - Google Patents

Analogifremgangsmaade til fremstilling af 4-aroyl-1,3-dihydro-2h-imidazol-2-oner eller et farmaceutisk acceptabelt metalsalt eller basisk ammoniumsalt deraf

Info

Publication number
DK160269C
DK160269C DK259080A DK259080A DK160269C DK 160269 C DK160269 C DK 160269C DK 259080 A DK259080 A DK 259080A DK 259080 A DK259080 A DK 259080A DK 160269 C DK160269 C DK 160269C
Authority
DK
Denmark
Prior art keywords
oner
aroyl
imidazol
dihydro
analogue
Prior art date
Application number
DK259080A
Other languages
Danish (da)
English (en)
Other versions
DK160269B (da
DK259080A (da
Inventor
Richard A Schnettler
Richard C Dage
J Martin Grisar
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK160269(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of DK259080A publication Critical patent/DK259080A/da
Publication of DK160269B publication Critical patent/DK160269B/da
Application granted granted Critical
Publication of DK160269C publication Critical patent/DK160269C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK259080A 1979-06-18 1980-06-17 Analogifremgangsmaade til fremstilling af 4-aroyl-1,3-dihydro-2h-imidazol-2-oner eller et farmaceutisk acceptabelt metalsalt eller basisk ammoniumsalt deraf DK160269C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US4980879 1979-06-18
US11920780A 1980-02-07 1980-02-07
US11920780 1980-02-07

Publications (3)

Publication Number Publication Date
DK259080A DK259080A (da) 1980-12-19
DK160269B DK160269B (da) 1991-02-18
DK160269C true DK160269C (da) 1991-07-22

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
DK259080A DK160269C (da) 1979-06-18 1980-06-17 Analogifremgangsmaade til fremstilling af 4-aroyl-1,3-dihydro-2h-imidazol-2-oner eller et farmaceutisk acceptabelt metalsalt eller basisk ammoniumsalt deraf

Country Status (20)

Country Link
AT (1) AT375349B (enrdf_load_html_response)
AU (1) AU532783B2 (enrdf_load_html_response)
CA (1) CA1132554A (enrdf_load_html_response)
CH (1) CH646155A5 (enrdf_load_html_response)
DE (1) DE3021792A1 (enrdf_load_html_response)
DK (1) DK160269C (enrdf_load_html_response)
ES (1) ES492255A0 (enrdf_load_html_response)
FR (1) FR2459233A1 (enrdf_load_html_response)
GB (1) GB2055364B (enrdf_load_html_response)
HK (1) HK61486A (enrdf_load_html_response)
HU (1) HU186736B (enrdf_load_html_response)
IE (1) IE50646B1 (enrdf_load_html_response)
IL (1) IL60243A (enrdf_load_html_response)
IT (1) IT1143922B (enrdf_load_html_response)
MY (1) MY8600709A (enrdf_load_html_response)
NL (2) NL193752C (enrdf_load_html_response)
NO (1) NO152841C (enrdf_load_html_response)
NZ (1) NZ193935A (enrdf_load_html_response)
PH (1) PH18683A (enrdf_load_html_response)
SE (2) SE447107B (enrdf_load_html_response)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4329470A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
GB2097792B (en) * 1981-05-04 1985-01-03 Merrell Dow Pharma 1,3-dihydro-2h-imidazol-2-ones
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CA2560528A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
WO2005092333A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
RU2008122978A (ru) 2005-11-09 2009-12-20 Комбинаторкс, Инкорпорейтед (Us) Способы, композиции и наборы для лечения медицинских состояний
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
KR102034748B1 (ko) 2011-03-01 2019-10-21 시너지 파마슈티컬즈 인코포레이티드 구아닐레이트 사이클라제 c 작용제의 제조 방법
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
HK1218629A1 (zh) 2013-02-25 2017-03-03 Bausch Health Ireland Limited 用於结肠清洁的鸟苷酸环化酶受体激动剂
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
HK1220611A1 (zh) 2013-03-15 2017-05-12 Bausch Health Ireland Limited 用於治療胃腸道病症的組成物
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
CN114539157B (zh) * 2022-03-03 2023-12-22 曲靖师范学院 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
IL60243A0 (en) 1980-09-16
AT375349B (de) 1984-07-25
PH18683A (en) 1985-08-29
NL300015I1 (nl) 2000-11-01
NO152841B (no) 1985-08-19
IT1143922B (it) 1986-10-29
SE464559B (sv) 1991-05-13
ES8105299A1 (es) 1981-06-01
FR2459233A1 (fr) 1981-01-09
CA1132554A (en) 1982-09-28
DE3021792C2 (enrdf_load_html_response) 1989-08-10
SE447107B (sv) 1986-10-27
IE50646B1 (en) 1986-06-11
SE8501452L (sv) 1985-03-25
IT8048997A0 (it) 1980-06-17
FR2459233B1 (enrdf_load_html_response) 1983-09-23
DE3021792A1 (de) 1981-01-22
CH646155A5 (de) 1984-11-15
GB2055364B (en) 1983-06-08
NZ193935A (en) 1985-05-31
NO152841C (no) 1985-11-27
DK160269B (da) 1991-02-18
IE801162L (en) 1980-12-18
IL60243A (en) 1987-01-30
HU186736B (en) 1985-09-30
NL300015I2 (nl) 2000-10-02
NL193752C (nl) 2000-09-04
MY8600709A (en) 1986-12-31
SE8501452D0 (sv) 1985-03-25
SE8004253L (sv) 1980-12-19
AU532783B2 (en) 1983-10-13
HK61486A (en) 1986-08-29
NO801796L (no) 1980-12-19
NL193752B (nl) 2000-05-01
ES492255A0 (es) 1981-06-01
NL8003498A (nl) 1980-12-22
AU5911880A (en) 1981-01-08
ATA314280A (de) 1983-12-15
DK259080A (da) 1980-12-19
GB2055364A (en) 1981-03-04

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