DK1573323T3 - Prion-proteinligander samt fremgangsmåder til anvendelse deraf - Google Patents
Prion-proteinligander samt fremgangsmåder til anvendelse derafInfo
- Publication number
- DK1573323T3 DK1573323T3 DK03808431.5T DK03808431T DK1573323T3 DK 1573323 T3 DK1573323 T3 DK 1573323T3 DK 03808431 T DK03808431 T DK 03808431T DK 1573323 T3 DK1573323 T3 DK 1573323T3
- Authority
- DK
- Denmark
- Prior art keywords
- prion protein
- ligands
- prion
- methods
- protein ligands
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2828—Prion diseases
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43042302P | 2002-12-03 | 2002-12-03 | |
PCT/US2003/038343 WO2004050851A2 (en) | 2002-12-03 | 2003-12-03 | Prion protein ligands and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1573323T3 true DK1573323T3 (da) | 2012-01-23 |
Family
ID=32469468
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03808431.5T DK1573323T3 (da) | 2002-12-03 | 2003-12-03 | Prion-proteinligander samt fremgangsmåder til anvendelse deraf |
DK10176707T DK2317317T3 (da) | 2002-12-03 | 2003-12-03 | Prion-proteinligander samt fremgangsmåder til anvendelse deraf |
DK10176708T DK2312318T3 (da) | 2002-12-03 | 2003-12-03 | Prion-proteinligander samt fremgangsmåder til anvendelse deraf |
DK08150151T DK1953551T3 (da) | 2002-12-03 | 2003-12-03 | Prion-proteinligander samt fremgangsmåder til anvendelse deraf |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10176707T DK2317317T3 (da) | 2002-12-03 | 2003-12-03 | Prion-proteinligander samt fremgangsmåder til anvendelse deraf |
DK10176708T DK2312318T3 (da) | 2002-12-03 | 2003-12-03 | Prion-proteinligander samt fremgangsmåder til anvendelse deraf |
DK08150151T DK1953551T3 (da) | 2002-12-03 | 2003-12-03 | Prion-proteinligander samt fremgangsmåder til anvendelse deraf |
Country Status (15)
Country | Link |
---|---|
US (3) | US7863411B2 (da) |
EP (4) | EP2312318B1 (da) |
JP (1) | JP4485367B2 (da) |
CN (3) | CN1739029B (da) |
AT (1) | ATE529744T1 (da) |
AU (2) | AU2003302500B2 (da) |
CA (2) | CA2507936C (da) |
DK (4) | DK1573323T3 (da) |
ES (4) | ES2375958T3 (da) |
HK (4) | HK1088948A1 (da) |
IL (3) | IL168904A (da) |
MX (2) | MXPA05005920A (da) |
NZ (3) | NZ560410A (da) |
PT (4) | PT2317317E (da) |
WO (1) | WO2004050851A2 (da) |
Families Citing this family (47)
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US7166471B2 (en) | 2001-05-31 | 2007-01-23 | Arete Associates | Misfolded protein sensor method in body fluids |
US20050026165A1 (en) * | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
CA2507936C (en) | 2002-12-03 | 2014-02-25 | The American National Red Cross | Prion protein ligands and methods of use |
EP1616036A4 (en) * | 2003-04-14 | 2007-03-21 | Pathogen Removal And Diagnosti | PROCESS FOR IDENTIFYING LIGANDS SPECIFIC TO STRUCTURAL FORMS OF PROTEINS |
US20060035242A1 (en) * | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
WO2005016127A2 (en) | 2003-08-13 | 2005-02-24 | Chiron Corporation | Prion-specific peptide reagents |
US20060057671A1 (en) * | 2004-09-10 | 2006-03-16 | Orser Cindy S | Immobilized probes and methods of detecting conformationally altered prion proteins |
JP5048522B2 (ja) * | 2005-02-15 | 2012-10-17 | エイディーライフ インコーポレイティッド | 誤って折り畳まれたタンパク質およびプリオンを検出する方法 |
US7834144B2 (en) | 2005-09-09 | 2010-11-16 | Novartis Ag | Prion-specific peptoid reagents |
US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
US7989160B2 (en) | 2006-02-13 | 2011-08-02 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in the process of bone remodeling |
WO2008005960A2 (en) * | 2006-07-07 | 2008-01-10 | Pall Corporation | Prion processing |
MX2009001079A (es) * | 2006-07-28 | 2009-02-10 | Adlyfe Inc | Sondas de peptido para diagnosis y terapeutica. |
CA2675039A1 (en) * | 2007-01-12 | 2008-07-17 | Alicon Ag | Method for removing prion protein |
AU2009243060A1 (en) * | 2008-04-30 | 2009-11-05 | Novartis Ag. | Assay for pathogenic conformers |
DK2419732T3 (da) * | 2009-04-15 | 2019-12-16 | Abraxis Bioscience Llc | Prionfrie nanopartikelsammensætninger og fremgangsmåder |
CA2755948A1 (en) | 2009-05-21 | 2010-11-25 | Larisa Cervenakova | Inhibition of prion protein propagation by receptor associated protein (rap), its derivatives, mimetics and synthetic peptides |
US8841429B2 (en) * | 2009-11-03 | 2014-09-23 | Vivonics, Inc. | Nucleic acid ligands against infectious prions |
US20130109581A1 (en) * | 2009-11-04 | 2013-05-02 | David Peretz | Positively charged species as binding reagents in the separation of protein aggregates from monomers |
US9162223B2 (en) | 2011-12-21 | 2015-10-20 | North Carolina State University | Alkaline-stable chromatographic resins |
ES2723885T3 (es) | 2012-07-19 | 2019-09-03 | Daiichi Sankyo Co Ltd | Anticuerpos anti-Siglec-15 |
CN103336124B (zh) * | 2012-12-11 | 2015-07-15 | 武汉工业学院 | 一种检测朊病毒蛋白(PrPSC)的方法和试剂盒 |
EP2995621A1 (en) | 2014-09-10 | 2016-03-16 | Previpharma AG | Ligands and methods for isolating or removing proteins |
CN113376364A (zh) | 2015-08-10 | 2021-09-10 | Essenlix 公司 | 步骤简化、小样品、快速、易使用的生物/化学分析装置和方法 |
CA2998587C (en) | 2015-09-14 | 2023-01-10 | Essenlix Corp. | Device and system for analyzing a sample, particularly blood, as well as methods of using the same |
CN108633304B (zh) | 2015-09-14 | 2020-08-14 | 艾森利克斯公司 | 采集分析蒸汽凝析,特别是呼出气凝析的装置与系统,以及使用方法 |
CN110312473B (zh) | 2016-12-21 | 2023-04-07 | 艾森利克斯公司 | 用于认证样本的装置和方法及其使用 |
WO2018148342A1 (en) | 2017-02-07 | 2018-08-16 | Essenlix Corporation | Compressed open flow assay and use |
WO2018148470A1 (en) | 2017-02-08 | 2018-08-16 | Essenlix Corporation | Sample collection and handling for delayed analysis |
CA3053002A1 (en) | 2017-02-08 | 2018-08-16 | Essenlix Corp. | Bio/chemical material extraction and assay |
CN111433606B (zh) | 2017-02-09 | 2024-05-24 | 上海宜晟生物科技有限公司 | 采用不同间距高度的测定 |
CN110770572B (zh) | 2017-02-09 | 2023-08-18 | Essenlix公司 | 比色测定 |
US11940382B2 (en) | 2017-02-09 | 2024-03-26 | Essenlix Corporation | Assay with amplification |
CN111448449A (zh) | 2017-02-16 | 2020-07-24 | Essenlix公司 | 采用纹理化表面的测定 |
EP3406632A1 (en) | 2017-05-23 | 2018-11-28 | S.I.S.S.A. Scuola Internazionale Superiore di Studi Avanzati | Ligands binding to prion protein for use in the treatment of synucleinopathies |
US11243201B2 (en) | 2017-08-01 | 2022-02-08 | Essenlix Corporation | Sample collection, holding and assaying |
CN112689758A (zh) | 2017-08-01 | 2021-04-20 | Essenlix公司 | 检查药物对微生物影响的装置和方法 |
US11280706B2 (en) | 2017-08-01 | 2022-03-22 | Essenlix Corporation | Dilution calibration |
US11393561B2 (en) | 2017-10-13 | 2022-07-19 | Essenlix Corporation | Devices and methods for authenticating a medical test and use of the same |
US11609224B2 (en) | 2017-10-26 | 2023-03-21 | Essenlix Corporation | Devices and methods for white blood cell analyses |
US10807095B2 (en) | 2017-10-26 | 2020-10-20 | Essenlix Corporation | Making and tracking assay card |
US11237113B2 (en) | 2017-10-26 | 2022-02-01 | Essenlix Corporation | Rapid pH measurement |
US11648551B2 (en) | 2017-12-12 | 2023-05-16 | Essenlix Corporation | Sample manipulation and assay with rapid temperature change |
CN112534259A (zh) | 2017-12-14 | 2021-03-19 | Essenlix公司 | 监测毛发的装置,系统和方法 |
US11156606B2 (en) | 2018-01-11 | 2021-10-26 | Essenlix Corporation | Homogeneous assay (II) |
US11885952B2 (en) | 2018-07-30 | 2024-01-30 | Essenlix Corporation | Optics, device, and system for assaying and imaging |
JP7376040B2 (ja) * | 2019-09-03 | 2023-11-08 | 国立大学法人京都工芸繊維大学 | 神経変性疾患におけるバイオマーカー分子の検出方法 |
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-
2003
- 2003-12-03 CA CA2507936A patent/CA2507936C/en not_active Expired - Lifetime
- 2003-12-03 CN CN2003801090433A patent/CN1739029B/zh not_active Expired - Lifetime
- 2003-12-03 EP EP20100176708 patent/EP2312318B1/en not_active Expired - Lifetime
- 2003-12-03 EP EP03808431A patent/EP1573323B1/en not_active Expired - Lifetime
- 2003-12-03 EP EP20100176707 patent/EP2317317B1/en not_active Expired - Lifetime
- 2003-12-03 PT PT10176707T patent/PT2317317E/pt unknown
- 2003-12-03 US US10/727,335 patent/US7863411B2/en active Active
- 2003-12-03 PT PT03808431T patent/PT1573323E/pt unknown
- 2003-12-03 ES ES03808431T patent/ES2375958T3/es not_active Expired - Lifetime
- 2003-12-03 MX MXPA05005920A patent/MXPA05005920A/es active IP Right Grant
- 2003-12-03 EP EP20080150151 patent/EP1953551B1/en not_active Expired - Lifetime
- 2003-12-03 DK DK03808431.5T patent/DK1573323T3/da active
- 2003-12-03 NZ NZ560410A patent/NZ560410A/en not_active IP Right Cessation
- 2003-12-03 DK DK10176707T patent/DK2317317T3/da active
- 2003-12-03 CN CN2011101132413A patent/CN102241741B/zh not_active Expired - Lifetime
- 2003-12-03 DK DK10176708T patent/DK2312318T3/da active
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