ATE354095T1 - Verfahren zur detektion von prp unter verwendung ein makrozyklischen ligand - Google Patents
Verfahren zur detektion von prp unter verwendung ein makrozyklischen ligandInfo
- Publication number
- ATE354095T1 ATE354095T1 AT03799682T AT03799682T ATE354095T1 AT E354095 T1 ATE354095 T1 AT E354095T1 AT 03799682 T AT03799682 T AT 03799682T AT 03799682 T AT03799682 T AT 03799682T AT E354095 T1 ATE354095 T1 AT E354095T1
- Authority
- AT
- Austria
- Prior art keywords
- prpsc
- macrocyclic ligand
- detecting prp
- immunodetection
- mal
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 2
- 108010067770 Endopeptidase K Proteins 0.000 abstract 1
- 102000029797 Prion Human genes 0.000 abstract 1
- 108091000054 Prion Proteins 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2828—Prion diseases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/823—Immunogenic carrier or carrier per se
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- Neurology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Transmission And Conversion Of Sensor Element Output (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0216383A FR2849205B1 (fr) | 2002-12-20 | 2002-12-20 | Procede d'amplification de la detection de la prpsc et utilisation d'un ligand adjuvant macrocyclique pour une telle amplification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE354095T1 true ATE354095T1 (de) | 2007-03-15 |
Family
ID=32406305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03799682T ATE354095T1 (de) | 2002-12-20 | 2003-12-19 | Verfahren zur detektion von prp unter verwendung ein makrozyklischen ligand |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7217530B2 (de) |
| EP (1) | EP1573337B1 (de) |
| JP (1) | JP2006510914A (de) |
| CN (1) | CN100380125C (de) |
| AT (1) | ATE354095T1 (de) |
| AU (1) | AU2003299390B2 (de) |
| BR (1) | BR0317080A (de) |
| DE (1) | DE60311871T2 (de) |
| DK (1) | DK1573337T3 (de) |
| ES (1) | ES2282733T3 (de) |
| FR (1) | FR2849205B1 (de) |
| MX (1) | MXPA05006766A (de) |
| PT (1) | PT1573337E (de) |
| WO (1) | WO2004059322A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2849205B1 (fr) * | 2002-12-20 | 2005-02-11 | Afssa | Procede d'amplification de la detection de la prpsc et utilisation d'un ligand adjuvant macrocyclique pour une telle amplification |
| DE10328125A1 (de) * | 2003-06-23 | 2005-01-13 | Roche Diagnostics Gmbh | Nachweis von Protease-resistentem Prion-Protein nach spontaner Transformationsreaktion |
| FR2865279A1 (fr) * | 2004-01-20 | 2005-07-22 | Biomerieux Sa | Procede de detection de la prp utilisant une molecule ayant au moins une charge positive et/ou au moins une liaison osidique et un ligand autre qu'un ligand proteique |
| FR2865280B1 (fr) * | 2004-01-20 | 2007-01-12 | Biomerieux Sa | Procede de detection de la prp utilisant une molecule ayant au moins une charge positive et/ou au moins une liaison osidique et un ligand autre qu'un ligand proteique |
| FR2888937B1 (fr) | 2005-07-21 | 2012-10-26 | Biomerieux Sa | Procede de detection des fcpa utilisant un agent d'agregation des fcpa et un agent de capture des agregats formes |
| EP3062104A1 (de) * | 2008-07-04 | 2016-08-31 | Sekisui Medical Co., Ltd. | Verfahren zur erhöhung der sensitivität bzw. verfahren zur vermeidung des einflusses von hämoglobin auf immunologische messungen |
| WO2013091074A1 (en) | 2011-12-21 | 2013-06-27 | Uvic Industry Partnerships Inc. | Method and array for identifying histone-code-related analytes |
| US10338037B2 (en) | 2015-08-18 | 2019-07-02 | Uvic Industry Partnerships Inc. | Compounds and conjugates for identifying and separating post-translationally modified analytes |
| CA3084887A1 (en) | 2019-06-25 | 2020-12-25 | Uvic Industry Partnerships Inc. | Compound and dimer complex embodiments for supramolecular sensing |
| CN113876760B (zh) * | 2021-10-26 | 2022-12-23 | 南开大学 | 杯芳烃和/或杯芳烃的衍生物在制备治疗创伤性脑损伤的药物中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312837A (en) * | 1991-01-29 | 1994-05-17 | Genelabs Technologies, Inc. | Method of treating viral infections with aryl macrocyclic compounds |
| US5342934A (en) * | 1992-06-19 | 1994-08-30 | The Trustees Of Columbia University In The City Of New York | Enantioselective receptor for amino acid derivatives, and other compounds |
| JP2000511880A (ja) * | 1996-04-05 | 2000-09-12 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | カリックスピロール、カリックスピリジノピロールおよびカリックスピリジン |
| WO1997041856A1 (en) * | 1996-05-08 | 1997-11-13 | Massachusetts Institute Of Technology | ORGANOMETALLIC LIGANDS FOR THE LOCALIZATION AND QUANTIFICATION OF AMYLOID IN VIVO AND $i(IN VITRO) |
| US5891641A (en) * | 1997-02-21 | 1999-04-06 | The Regents Of The University Of California | Assay for disease related conformation of a protein |
| US6150172A (en) * | 1999-01-08 | 2000-11-21 | The United States Of America As Represented By The Secretary Of Agriculture | Method and kit for extracting prion protein |
| EP1216258A1 (de) * | 1999-09-28 | 2002-06-26 | Universität Zürich | Faktoren mit prionen bindender aktivität im serum und plasma sowie mittel zur bestimmung von übertragbaren spongiformen encephalopathien |
| EP1272509A2 (de) * | 2000-04-05 | 2003-01-08 | V.I. Technologies, Inc. | Peptidische bindstoffe für prione und verfahren zu deren verwendung |
| DE10107083C2 (de) * | 2001-02-13 | 2003-02-20 | Abdulgabar Salama | Pentosan Polysulfat als Ligand zum Nachweis von Prionen |
| DE10119713A1 (de) * | 2001-04-21 | 2002-10-24 | Prionics Ag Zuerich | Verfahren zur Untersuchung von Prion-Protein enthaltenden Proben auf das eventuelle Vorliegen der PrPSc-Form |
| FR2849205B1 (fr) * | 2002-12-20 | 2005-02-11 | Afssa | Procede d'amplification de la detection de la prpsc et utilisation d'un ligand adjuvant macrocyclique pour une telle amplification |
-
2002
- 2002-12-20 FR FR0216383A patent/FR2849205B1/fr not_active Expired - Fee Related
-
2003
- 2003-12-19 WO PCT/FR2003/003857 patent/WO2004059322A1/fr active IP Right Grant
- 2003-12-19 JP JP2004563299A patent/JP2006510914A/ja active Pending
- 2003-12-19 CN CNB2003801067742A patent/CN100380125C/zh not_active Expired - Fee Related
- 2003-12-19 DK DK03799682T patent/DK1573337T3/da active
- 2003-12-19 DE DE60311871T patent/DE60311871T2/de not_active Expired - Lifetime
- 2003-12-19 BR BR0317080-2A patent/BR0317080A/pt not_active IP Right Cessation
- 2003-12-19 AU AU2003299390A patent/AU2003299390B2/en not_active Ceased
- 2003-12-19 MX MXPA05006766A patent/MXPA05006766A/es active IP Right Grant
- 2003-12-19 AT AT03799682T patent/ATE354095T1/de not_active IP Right Cessation
- 2003-12-19 ES ES03799682T patent/ES2282733T3/es not_active Expired - Lifetime
- 2003-12-19 PT PT03799682T patent/PT1573337E/pt unknown
- 2003-12-19 EP EP03799682A patent/EP1573337B1/de not_active Expired - Lifetime
-
2005
- 2005-06-09 US US11/148,945 patent/US7217530B2/en not_active Expired - Fee Related
-
2007
- 2007-02-01 US US11/701,334 patent/US20070154885A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003299390A1 (en) | 2004-07-22 |
| EP1573337B1 (de) | 2007-02-14 |
| EP1573337A1 (de) | 2005-09-14 |
| FR2849205B1 (fr) | 2005-02-11 |
| ES2282733T3 (es) | 2007-10-16 |
| WO2004059322A1 (fr) | 2004-07-15 |
| US20070154885A1 (en) | 2007-07-05 |
| AU2003299390B2 (en) | 2007-11-01 |
| US20060019311A1 (en) | 2006-01-26 |
| DE60311871T2 (de) | 2007-10-31 |
| AU2003299390A8 (en) | 2004-07-22 |
| MXPA05006766A (es) | 2006-02-17 |
| DE60311871D1 (de) | 2007-03-29 |
| BR0317080A (pt) | 2005-10-25 |
| US7217530B2 (en) | 2007-05-15 |
| PT1573337E (pt) | 2007-05-31 |
| CN1729397A (zh) | 2006-02-01 |
| DK1573337T3 (da) | 2007-06-11 |
| JP2006510914A (ja) | 2006-03-30 |
| WO2004059322A8 (fr) | 2005-07-14 |
| FR2849205A1 (fr) | 2004-06-25 |
| CN100380125C (zh) | 2008-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |