DE602006013143D1 - Verfahren zum nachweis aggregatbildender zirkulierender proteinformen und mittel zum einfangen gebildeter aggregate - Google Patents
Verfahren zum nachweis aggregatbildender zirkulierender proteinformen und mittel zum einfangen gebildeter aggregateInfo
- Publication number
- DE602006013143D1 DE602006013143D1 DE602006013143T DE602006013143T DE602006013143D1 DE 602006013143 D1 DE602006013143 D1 DE 602006013143D1 DE 602006013143 T DE602006013143 T DE 602006013143T DE 602006013143 T DE602006013143 T DE 602006013143T DE 602006013143 D1 DE602006013143 D1 DE 602006013143D1
- Authority
- DE
- Germany
- Prior art keywords
- capturing
- protein forms
- circulating protein
- forms
- aggregate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 3
- 230000002776 aggregation Effects 0.000 abstract 2
- 238000004220 aggregation Methods 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0507757A FR2888937B1 (fr) | 2005-07-21 | 2005-07-21 | Procede de detection des fcpa utilisant un agent d'agregation des fcpa et un agent de capture des agregats formes |
PCT/FR2006/001641 WO2007010110A2 (fr) | 2005-07-21 | 2006-07-07 | Procede de detection des fpca utilisant un agent d'agregation des fpca et un agent de capture des agregats formes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006013143D1 true DE602006013143D1 (de) | 2010-05-06 |
Family
ID=36011928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006013143T Active DE602006013143D1 (de) | 2005-07-21 | 2006-07-07 | Verfahren zum nachweis aggregatbildender zirkulierender proteinformen und mittel zum einfangen gebildeter aggregate |
Country Status (8)
Country | Link |
---|---|
US (1) | US8158441B2 (de) |
EP (1) | EP1907861B1 (de) |
JP (2) | JP5693816B2 (de) |
AT (1) | ATE462140T1 (de) |
DE (1) | DE602006013143D1 (de) |
ES (1) | ES2343474T3 (de) |
FR (1) | FR2888937B1 (de) |
WO (1) | WO2007010110A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2931695B1 (fr) * | 2008-05-28 | 2010-06-25 | Centre Nat Rech Scient | Procede d'extraction selective de proteines membranaires avec les calixarenes |
JP5732292B2 (ja) | 2011-03-28 | 2015-06-10 | 日東電工株式会社 | スルホン酸基含有ジアミン化合物とその製造方法 |
WO2013091074A1 (en) * | 2011-12-21 | 2013-06-27 | Uvic Industry Partnerships Inc. | Method and array for identifying histone-code-related analytes |
KR101658620B1 (ko) * | 2014-12-02 | 2016-09-23 | 주식회사 피플바이오 | 응집형-형성 폴리펩타이드의 응집형을 검출하는 방법 |
US10338037B2 (en) | 2015-08-18 | 2019-07-02 | Uvic Industry Partnerships Inc. | Compounds and conjugates for identifying and separating post-translationally modified analytes |
ES2804541T3 (es) * | 2015-11-30 | 2021-02-08 | Univ Wien | Compuesto para su uso en la prevención y el tratamiento de enfermedades neurodegenerativas |
EP3207925A1 (de) * | 2016-02-22 | 2017-08-23 | Universität Wien | Zusammensetzung zur verwendung bei der vorbeugung und behandlung neurodegenerativer erkrankungen |
US11415574B2 (en) * | 2017-03-31 | 2022-08-16 | NeuroDiagnostics LLC | Lymphocyte-based morphometric test for alzheimer's disease |
CA3084887A1 (en) | 2019-06-25 | 2020-12-25 | Uvic Industry Partnerships Inc. | Compound and dimer complex embodiments for supramolecular sensing |
CN111517947B (zh) * | 2020-03-18 | 2022-05-24 | 西北师范大学 | 一种基于功能化的双边柱[5]芳烃传感器分子及其合成和应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6365414B1 (en) * | 1994-08-26 | 2002-04-02 | The General Hospital Corporation | Vitro system for determining formation of Aβ amyloid |
US5639626A (en) | 1994-11-15 | 1997-06-17 | Chiron Diagnostics Corporation | Reagents for specific binding assays |
WO1997041856A1 (en) * | 1996-05-08 | 1997-11-13 | Massachusetts Institute Of Technology | ORGANOMETALLIC LIGANDS FOR THE LOCALIZATION AND QUANTIFICATION OF AMYLOID IN VIVO AND $i(IN VITRO) |
GB9610829D0 (en) * | 1996-05-23 | 1996-07-31 | Medical Res Council | Screening of agents for treatment of azlheimers disease |
CA2301142A1 (en) * | 1997-08-14 | 1999-02-25 | The Regents Of The University Of California | Fluorescent amyloid a.beta. peptides and uses thereof |
MY128673A (en) * | 1997-10-30 | 2007-02-28 | Shell Int Research | Catalytic hydrolysis of alkylene oxides |
GB9908059D0 (en) * | 1999-04-09 | 1999-06-02 | Imp College Innovations Ltd | Diagnosis and treatment of diseases |
AU2002241909A1 (en) * | 2001-01-19 | 2002-07-30 | Baxter Healthcare S.A. | Method of detecting prp protein and kits therefor |
DE10107083C2 (de) | 2001-02-13 | 2003-02-20 | Abdulgabar Salama | Pentosan Polysulfat als Ligand zum Nachweis von Prionen |
DE10119713A1 (de) | 2001-04-21 | 2002-10-24 | Prionics Ag Zuerich | Verfahren zur Untersuchung von Prion-Protein enthaltenden Proben auf das eventuelle Vorliegen der PrPSc-Form |
RU2309410C2 (ru) * | 2002-02-28 | 2007-10-27 | Майкроусенс Байофейдж Лимитед | Связывание патологических форм прионовых белков |
WO2004041779A2 (en) * | 2002-11-01 | 2004-05-21 | Proteotech, Inc. | Amyloid plaque formation by glycosaminoglycans |
FR2849205B1 (fr) * | 2002-12-20 | 2005-02-11 | Afssa | Procede d'amplification de la detection de la prpsc et utilisation d'un ligand adjuvant macrocyclique pour une telle amplification |
FR2849204B1 (fr) * | 2002-12-20 | 2005-02-11 | Afssa | Procede de detection de la prpsc utilisant un antibiotique d de la famille des aminoglycosides pour l'elimination et la detection de la prpsc dans des echantillons biologiques |
IL158010A0 (en) | 2003-09-18 | 2004-03-28 | Hadasit Med Res Service | Methods and kits for the detection of prion diseases |
FR2865280B1 (fr) * | 2004-01-20 | 2007-01-12 | Biomerieux Sa | Procede de detection de la prp utilisant une molecule ayant au moins une charge positive et/ou au moins une liaison osidique et un ligand autre qu'un ligand proteique |
-
2005
- 2005-07-21 FR FR0507757A patent/FR2888937B1/fr not_active Expired - Fee Related
-
2006
- 2006-07-07 AT AT06778816T patent/ATE462140T1/de not_active IP Right Cessation
- 2006-07-07 JP JP2008522002A patent/JP5693816B2/ja not_active Expired - Fee Related
- 2006-07-07 US US11/988,402 patent/US8158441B2/en not_active Expired - Fee Related
- 2006-07-07 WO PCT/FR2006/001641 patent/WO2007010110A2/fr not_active Application Discontinuation
- 2006-07-07 DE DE602006013143T patent/DE602006013143D1/de active Active
- 2006-07-07 ES ES06778816T patent/ES2343474T3/es active Active
- 2006-07-07 EP EP06778816A patent/EP1907861B1/de not_active Not-in-force
-
2014
- 2014-06-30 JP JP2014133990A patent/JP5785642B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE462140T1 (de) | 2010-04-15 |
JP2009501922A (ja) | 2009-01-22 |
FR2888937A1 (fr) | 2007-01-26 |
US8158441B2 (en) | 2012-04-17 |
JP2014178337A (ja) | 2014-09-25 |
JP5693816B2 (ja) | 2015-04-01 |
FR2888937B1 (fr) | 2012-10-26 |
JP5785642B2 (ja) | 2015-09-30 |
ES2343474T3 (es) | 2010-08-02 |
WO2007010110A2 (fr) | 2007-01-25 |
EP1907861A2 (de) | 2008-04-09 |
US20100062540A1 (en) | 2010-03-11 |
EP1907861B1 (de) | 2010-03-24 |
WO2007010110A3 (fr) | 2007-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |