DK1523335T3 - Injicerbar depotformulering omfattende iloperidonkrystaller - Google Patents

Injicerbar depotformulering omfattende iloperidonkrystaller

Info

Publication number
DK1523335T3
DK1523335T3 DK03756455T DK03756455T DK1523335T3 DK 1523335 T3 DK1523335 T3 DK 1523335T3 DK 03756455 T DK03756455 T DK 03756455T DK 03756455 T DK03756455 T DK 03756455T DK 1523335 T3 DK1523335 T3 DK 1523335T3
Authority
DK
Denmark
Prior art keywords
crystals
injectable formulation
size
iloperidone
correlated
Prior art date
Application number
DK03756455T
Other languages
Danish (da)
English (en)
Inventor
Alexandra Glausch
Dierk Wieckhusen
Markus Ahlheim
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9940486&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1523335(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1523335T3 publication Critical patent/DK1523335T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK03756455T 2002-07-15 2003-07-14 Injicerbar depotformulering omfattende iloperidonkrystaller DK1523335T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216416.8A GB0216416D0 (en) 2002-07-15 2002-07-15 Organic compounds
PCT/EP2003/007619 WO2004006886A2 (en) 2002-07-15 2003-07-14 Injectable depot formulation comprising crystals of iloperidone

Publications (1)

Publication Number Publication Date
DK1523335T3 true DK1523335T3 (da) 2007-01-29

Family

ID=9940486

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03756455T DK1523335T3 (da) 2002-07-15 2003-07-14 Injicerbar depotformulering omfattende iloperidonkrystaller

Country Status (15)

Country Link
US (5) US20050250813A1 (enExample)
EP (1) EP1523335B1 (enExample)
JP (2) JP5392961B2 (enExample)
AT (1) ATE348635T1 (enExample)
AU (1) AU2003281154B2 (enExample)
CA (1) CA2492467C (enExample)
CY (1) CY1106305T1 (enExample)
DE (1) DE60310564T2 (enExample)
DK (1) DK1523335T3 (enExample)
ES (1) ES2279153T3 (enExample)
GB (1) GB0216416D0 (enExample)
NZ (1) NZ537598A (enExample)
PT (1) PT1523335E (enExample)
WO (1) WO2004006886A2 (enExample)
ZA (1) ZA200410323B (enExample)

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GB0216416D0 (en) 2002-07-15 2002-08-21 Novartis Ag Organic compounds
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CN102633786B (zh) * 2012-04-18 2013-11-27 吉林三善恩科技开发有限公司 一种伊潘立酮药物共晶及其制备方法
CN102659771B (zh) * 2012-04-18 2013-11-27 吉林三善恩科技开发有限公司 一种伊潘立酮药物共晶及其制备方法
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US11090285B2 (en) 2013-11-12 2021-08-17 Vanda Pharmaceuticals Inc Treatment of circadian rhythm disorders
CN103599074A (zh) * 2013-11-26 2014-02-26 重庆医药工业研究院有限责任公司 一种伊潘立酮缓释微球及其制备方法
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Also Published As

Publication number Publication date
AU2003281154B2 (en) 2006-10-12
US8293765B2 (en) 2012-10-23
GB0216416D0 (en) 2002-08-21
WO2004006886A3 (en) 2004-02-19
DE60310564T2 (de) 2007-10-04
NZ537598A (en) 2006-07-28
JP5392961B2 (ja) 2014-01-22
CY1106305T1 (el) 2011-10-12
PT1523335E (pt) 2007-02-28
DE60310564D1 (de) 2007-02-01
ZA200410323B (en) 2006-06-28
CA2492467A1 (en) 2004-01-22
ES2279153T3 (es) 2007-08-16
CA2492467C (en) 2010-03-16
US8614232B2 (en) 2013-12-24
AU2003281154A1 (en) 2004-02-02
US20110212141A1 (en) 2011-09-01
WO2004006886A2 (en) 2004-01-22
US20120156264A1 (en) 2012-06-21
ATE348635T1 (de) 2007-01-15
JP5670698B2 (ja) 2015-02-18
JP2011016849A (ja) 2011-01-27
EP1523335B1 (en) 2006-12-20
JP2005533093A (ja) 2005-11-04
EP1523335A2 (en) 2005-04-20
US8227488B2 (en) 2012-07-24
US20050250813A1 (en) 2005-11-10
HK1076029A1 (en) 2006-01-06
US20090099232A1 (en) 2009-04-16
US20130012542A1 (en) 2013-01-10

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