ATE175207T1 - Intrazelluläre inhibitoren der aldose-reduktase - Google Patents

Intrazelluläre inhibitoren der aldose-reduktase

Info

Publication number
ATE175207T1
ATE175207T1 AT93925050T AT93925050T ATE175207T1 AT E175207 T1 ATE175207 T1 AT E175207T1 AT 93925050 T AT93925050 T AT 93925050T AT 93925050 T AT93925050 T AT 93925050T AT E175207 T1 ATE175207 T1 AT E175207T1
Authority
AT
Austria
Prior art keywords
aldose reductase
intracellular inhibitors
intrinsic
reductase inhibitor
intracellular
Prior art date
Application number
AT93925050T
Other languages
English (en)
Inventor
Peter F Kador
Yukio Takahashi
Tomoyuki Terada
Libaniel Rodriguez
Matteo Schaffhauser
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of ATE175207T1 publication Critical patent/ATE175207T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93925050T 1992-10-26 1993-10-26 Intrazelluläre inhibitoren der aldose-reduktase ATE175207T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96697092A 1992-10-26 1992-10-26

Publications (1)

Publication Number Publication Date
ATE175207T1 true ATE175207T1 (de) 1999-01-15

Family

ID=25512135

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93925050T ATE175207T1 (de) 1992-10-26 1993-10-26 Intrazelluläre inhibitoren der aldose-reduktase

Country Status (8)

Country Link
US (3) US5560936A (de)
EP (1) EP0686164B1 (de)
JP (1) JPH08502967A (de)
AT (1) ATE175207T1 (de)
AU (1) AU676235B2 (de)
CA (1) CA2147494A1 (de)
DE (1) DE69322882T2 (de)
WO (1) WO1994010206A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010206A1 (en) * 1992-10-26 1994-05-11 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES Intrinsic inhibitors of aldose reductase
US5695785A (en) * 1996-06-27 1997-12-09 Masonic Medical Research Laboratory Kidney extract for treatment of systematic lupus erythematosus
US6555573B2 (en) * 2000-12-21 2003-04-29 The Quigley Corporation Method and composition for the topical treatment of diabetic neuropathy
CN101029338B (zh) * 2001-03-30 2010-05-19 香港中文大学 通过醛糖还原酶基因型确定白内障的风险率
EP1298223A3 (de) * 2001-09-28 2003-07-23 Pfizer Products Inc. Methoden die mit der A-C Wiederholungs-Z-Sequenz stromaufwärts des Aldosereduktasegens in Zusammenhang stehen
DK1539261T3 (da) * 2002-09-10 2006-08-07 Scil Technology Gmbh Metalimplantat belagt under nedsat oxygenkoncentration med osteoinduktiv protein
US6989167B2 (en) * 2003-06-25 2006-01-24 Procter + Gamble Co. Method for reducing acrylamide in foods comprising reducing the level of reducing sugars, foods having reduced levels of acrylamide, and article of commerce

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5646897A (en) * 1979-09-26 1981-04-28 Seiichi Shibata Novel glycopeptide
US5153211A (en) * 1983-09-14 1992-10-06 Alcon Laboratories, Inc. Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase
JPS6413019A (en) * 1987-06-09 1989-01-17 Tsumura & Co Aldose reductase inhibitor
IT1223302B (it) * 1987-09-16 1990-09-19 Baldacci Lab Spa Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengono
JPH01121221A (ja) * 1987-11-02 1989-05-12 Toyo Pharma- Kk アルドース還元酵素阻害剤
JPH02225485A (ja) * 1989-02-27 1990-09-07 Taiho Yakuhin Kogyo Kk チエノピリミジン―３―酢酸誘導体
JPH0495025A (ja) * 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd アルドースリダクターゼ阻害剤
WO1994010206A1 (en) * 1992-10-26 1994-05-11 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES Intrinsic inhibitors of aldose reductase
US7966970B2 (en) * 2005-07-19 2011-06-28 M Management-Tex, Llc Dairy inflation

Also Published As

Publication number Publication date
EP0686164A1 (de) 1995-12-13
WO1994010206A1 (en) 1994-05-11
AU5450894A (en) 1994-05-24
DE69322882T2 (de) 1999-08-19
JPH08502967A (ja) 1996-04-02
DE69322882D1 (de) 1999-02-11
EP0686164B1 (de) 1998-12-30
US5738878A (en) 1998-04-14
US5928670A (en) 1999-07-27
AU676235B2 (en) 1997-03-06
US5560936A (en) 1996-10-01
CA2147494A1 (en) 1994-05-11

Similar Documents

Publication Publication Date Title
EA200000433A1 (ru) Комбинация ингибитора альдозоредуктазы и ингибитора гликогенфосфорилазы
ES2175087T3 (es) Compuestos triciclicos utiles en el tratamiento de trastornos de proliferacion celular.
TR199902626T2 (xx) Enflamasyon tedavisi i�in ikameli benzopiran t�revleri.
EA200100103A1 (ru) Ингибиторы адгезии клеток
ES2194987T3 (es) Compuestos triciclicos utiles para inhibir la farnesil-protein-transferasa.
ES2133807T3 (es) Compuestos de peptidilo y su uso terapeutico como inhibidores de metaloproteasas.
TR200000481T2 (tr) N-Alkonoilfenilalenin türevleri.
ES2085876T3 (es) Derivado de bifenilmetano, su utilizacion y composiciones farmacologicas que contienen el mismo.
EA200200097A1 (ru) Имидазоимидазолы и триазолы в качестве противовоспалительных агентов
AU8163398A (en) Inhibitors of alpha4beta1mediated cell adhesion
MA23355A1 (fr) COMPOSES SULFONAMIDES TRICYCLIQUES UTILES POUR l'INHIBITION DE LA FONCTION PROTEINE G
NO304186B1 (no) 1H-indol-3-glykosylamid og farmas°ytisk formulering
DK0650483T3 (da) (3R,4R)-Delta6-tetrahydrocannabinol-7-syrer
KR950700323A (ko) 엔케팔리나제 및 안지오텐신 전환 효소의 억제제로서 유용한 아미노아세틸머캅토아세틸아미드 유도체(Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ACE)
ES2118250T3 (es) Combinaciones germicidas de substancias activas.
ATE168373T1 (de) Benzofuranyl- und thiophenylalkancarbonsäurederivate
TR199800585T2 (xx) COX-2 �nhibit�rleri Olarak (Metils�lfonil)Fenil-2-(5H)-Furanonlar.
DK0726899T3 (da) Nye pyrazincarboxamidderivater, deres fremstilling og deres anvendelse i lægemidler
BR0108396A (pt) Derivados de pirimidina-4-0na como inibidores de ldl-pla(2)
TNSN87033A1 (fr) TOLUNITRILES SUBSTITUES PAR DESα - HETEROCYCLES
DE69928697D1 (de) Sulfohydroxamsäure and sulfohydroxamate und ihre verwendung als mek-inhibitoren
EA200000920A1 (ru) Производные бициклических гидроксамовых кислот
AU6894800A (en) Caspase inhibitors and uses thereof
DE69723863D1 (de) Chinoline und deren therapeutische verwendung
AU2209500A (en) Inhibitors of alpha4beta1 mediated cell adhesion

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties