DE69322882D1 - Intrazelluläre inhibitoren der aldose-reduktase - Google Patents

Intrazelluläre inhibitoren der aldose-reduktase

Info

Publication number
DE69322882D1
DE69322882D1 DE69322882T DE69322882T DE69322882D1 DE 69322882 D1 DE69322882 D1 DE 69322882D1 DE 69322882 T DE69322882 T DE 69322882T DE 69322882 T DE69322882 T DE 69322882T DE 69322882 D1 DE69322882 D1 DE 69322882D1
Authority
DE
Germany
Prior art keywords
aldose reductase
intracellular inhibitors
intrinsic
reductase inhibitor
intracellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69322882T
Other languages
English (en)
Other versions
DE69322882T2 (de
Inventor
Peter Kador
Yukio Takahashi
Tomoyuki Terada
Libaniel Rodriguez
Matteo Schaffhauser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of DE69322882D1 publication Critical patent/DE69322882D1/de
Publication of DE69322882T2 publication Critical patent/DE69322882T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69322882T 1992-10-26 1993-10-26 Intrazelluläre inhibitoren der aldose-reduktase Expired - Fee Related DE69322882T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96697092A 1992-10-26 1992-10-26
PCT/US1993/010241 WO1994010206A1 (en) 1992-10-26 1993-10-26 Intrinsic inhibitors of aldose reductase

Publications (2)

Publication Number Publication Date
DE69322882D1 true DE69322882D1 (de) 1999-02-11
DE69322882T2 DE69322882T2 (de) 1999-08-19

Family

ID=25512135

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69322882T Expired - Fee Related DE69322882T2 (de) 1992-10-26 1993-10-26 Intrazelluläre inhibitoren der aldose-reduktase

Country Status (8)

Country Link
US (3) US5560936A (de)
EP (1) EP0686164B1 (de)
JP (1) JPH08502967A (de)
AT (1) ATE175207T1 (de)
AU (1) AU676235B2 (de)
CA (1) CA2147494A1 (de)
DE (1) DE69322882T2 (de)
WO (1) WO1994010206A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69322882T2 (de) * 1992-10-26 1999-08-19 Us Health Intrazelluläre inhibitoren der aldose-reduktase
US5695785A (en) * 1996-06-27 1997-12-09 Masonic Medical Research Laboratory Kidney extract for treatment of systematic lupus erythematosus
US6555573B2 (en) * 2000-12-21 2003-04-29 The Quigley Corporation Method and composition for the topical treatment of diabetic neuropathy
WO2002079506A1 (en) * 2001-03-30 2002-10-10 The Chinese University Of Hong Kong Determination of risk factors for cataract by aldose reductase genotype
EP1298223A3 (de) * 2001-09-28 2003-07-23 Pfizer Products Inc. Methoden die mit der A-C Wiederholungs-Z-Sequenz stromaufwärts des Aldosereduktasegens in Zusammenhang stehen
US7763270B2 (en) * 2002-09-10 2010-07-27 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
US6989167B2 (en) * 2003-06-25 2006-01-24 Procter + Gamble Co. Method for reducing acrylamide in foods comprising reducing the level of reducing sugars, foods having reduced levels of acrylamide, and article of commerce

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5646897A (en) * 1979-09-26 1981-04-28 Seiichi Shibata Novel glycopeptide
US5153211A (en) * 1983-09-14 1992-10-06 Alcon Laboratories, Inc. Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase
JPS6413019A (en) * 1987-06-09 1989-01-17 Tsumura & Co Aldose reductase inhibitor
IT1223302B (it) * 1987-09-16 1990-09-19 Baldacci Lab Spa Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengono
JPH01121221A (ja) * 1987-11-02 1989-05-12 Toyo Pharma- Kk アルドース還元酵素阻害剤
JPH02225485A (ja) * 1989-02-27 1990-09-07 Taiho Yakuhin Kogyo Kk チエノピリミジン―３―酢酸誘導体
JPH0495025A (ja) * 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd アルドースリダクターゼ阻害剤
DE69322882T2 (de) * 1992-10-26 1999-08-19 Us Health Intrazelluläre inhibitoren der aldose-reduktase
US7966970B2 (en) * 2005-07-19 2011-06-28 M Management-Tex, Llc Dairy inflation

Also Published As

Publication number Publication date
AU676235B2 (en) 1997-03-06
AU5450894A (en) 1994-05-24
US5560936A (en) 1996-10-01
EP0686164B1 (de) 1998-12-30
US5928670A (en) 1999-07-27
WO1994010206A1 (en) 1994-05-11
ATE175207T1 (de) 1999-01-15
DE69322882T2 (de) 1999-08-19
JPH08502967A (ja) 1996-04-02
CA2147494A1 (en) 1994-05-11
US5738878A (en) 1998-04-14
EP0686164A1 (de) 1995-12-13

Similar Documents

Publication Publication Date Title
EA200000433A1 (ru) Комбинация ингибитора альдозоредуктазы и ингибитора гликогенфосфорилазы
ES2175087T3 (es) Compuestos triciclicos utiles en el tratamiento de trastornos de proliferacion celular.
TR199902626T2 (xx) Enflamasyon tedavisi i�in ikameli benzopiran t�revleri.
ES2161291T3 (es) N-(indol-2-carbonil)amidas y derivados como inhibidores de la glucogeno fosforilasa.
EA200100103A1 (ru) Ингибиторы адгезии клеток
DE69818049D1 (de) Inhibitoren der alpha4-beta1 vermittelten zelladhäsion
ES2194987T3 (es) Compuestos triciclicos utiles para inhibir la farnesil-protein-transferasa.
ES2133807T3 (es) Compuestos de peptidilo y su uso terapeutico como inhibidores de metaloproteasas.
TR200000481T2 (tr) N-Alkonoilfenilalenin türevleri.
EA200200097A1 (ru) Имидазоимидазолы и триазолы в качестве противовоспалительных агентов
NO304186B1 (no) 1H-indol-3-glykosylamid og farmas°ytisk formulering
DK0650483T3 (da) (3R,4R)-Delta6-tetrahydrocannabinol-7-syrer
DK0833839T3 (da) Heterocykliske peptidylforbindelser, der er nyttige til behandling af thrombinrelaterede sygdomme
KR950700323A (ko) 엔케팔리나제 및 안지오텐신 전환 효소의 억제제로서 유용한 아미노아세틸머캅토아세틸아미드 유도체(Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ACE)
ATE168373T1 (de) Benzofuranyl- und thiophenylalkancarbonsäurederivate
TR199800585T2 (xx) COX-2 �nhibit�rleri Olarak (Metils�lfonil)Fenil-2-(5H)-Furanonlar.
DK0726899T3 (da) Nye pyrazincarboxamidderivater, deres fremstilling og deres anvendelse i lægemidler
DE69723863D1 (de) Chinoline und deren therapeutische verwendung
AU2209500A (en) Inhibitors of alpha4beta1 mediated cell adhesion
EA200400708A1 (ru) Ингибиторы 11-бета-гидроксистероиддегидрогеназы типа 1
DE69322882D1 (de) Intrazelluläre inhibitoren der aldose-reduktase
ATE60763T1 (de) Pyrrolidinylamidesterderivate mit antiprolylendopeptidaseaktivitaet, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen.
DE69834271D1 (de) Steroid-3-o-sulfamat-derivate als estronsulfatase-hemmer
ATE253571T1 (de) 2-heterozyklisch-5-hydroxy-1,3-pyrimidinen verwendbar als entzündungswidrigesmittel
RU94038042A (ru) Производные гексагидроазепинов, фармацевтическая композиция на их основе и антипсихотропный агент

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee