IT1223302B - Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengono - Google Patents
Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengonoInfo
- Publication number
- IT1223302B IT1223302B IT21930/87A IT2193087A IT1223302B IT 1223302 B IT1223302 B IT 1223302B IT 21930/87 A IT21930/87 A IT 21930/87A IT 2193087 A IT2193087 A IT 2193087A IT 1223302 B IT1223302 B IT 1223302B
- Authority
- IT
- Italy
- Prior art keywords
- aldose
- chem
- contain
- pharmaceutical compositions
- compounds derived
- Prior art date
Links
- 102000016912 Aldehyde Reductase Human genes 0.000 title abstract 2
- 108010053754 Aldehyde reductase Proteins 0.000 title abstract 2
- 230000002255 enzymatic effect Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- -1 benzensulfonamido Chemical class 0.000 abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000033808 peripheral neuropathy Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21930/87A IT1223302B (it) | 1987-09-16 | 1987-09-16 | Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengono |
| AT88115001T ATE106399T1 (de) | 1987-09-16 | 1988-09-14 | Sulfonamidderivate, inhibitoren für das aldose- reduktase-enzymsystem und diese enthaltende pharmazeutische zusammenstellungen. |
| DE3889820T DE3889820T2 (de) | 1987-09-16 | 1988-09-14 | Sulfonamidderivate, Inhibitoren für das Aldose-Reduktase-Enzymsystem und diese enthaltende pharmazeutische Zusammenstellungen. |
| EP88115001A EP0307879B1 (en) | 1987-09-16 | 1988-09-14 | Sulfonamido derivatives inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them |
| CA000577438A CA1332062C (en) | 1987-09-16 | 1988-09-15 | Sulfonamido derivatives inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them |
| AU22276/88A AU618551B2 (en) | 1987-09-16 | 1988-09-15 | Sulfonamido derivative inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them |
| ZA886935A ZA886935B (en) | 1987-09-16 | 1988-09-16 | Sulfonamido derivatives inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them |
| JP63230214A JP2596986B2 (ja) | 1987-09-16 | 1988-09-16 | アルドースレダクターゼ酵素系を抑制するスルホンアミド誘導体及びそれらを含有する製薬学的組成物 |
| US07/245,165 US4927849A (en) | 1987-09-16 | 1988-09-16 | Sulfonamido derivatives inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them |
| US07/476,762 US5066676A (en) | 1987-09-16 | 1990-02-08 | Sulfonamido derivative inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21930/87A IT1223302B (it) | 1987-09-16 | 1987-09-16 | Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengono |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8721930A0 IT8721930A0 (it) | 1987-09-16 |
| IT1223302B true IT1223302B (it) | 1990-09-19 |
Family
ID=11188976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT21930/87A IT1223302B (it) | 1987-09-16 | 1987-09-16 | Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengono |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US4927849A (it) |
| EP (1) | EP0307879B1 (it) |
| JP (1) | JP2596986B2 (it) |
| AT (1) | ATE106399T1 (it) |
| AU (1) | AU618551B2 (it) |
| CA (1) | CA1332062C (it) |
| DE (1) | DE3889820T2 (it) |
| IT (1) | IT1223302B (it) |
| ZA (1) | ZA886935B (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5560936A (en) * | 1992-10-26 | 1996-10-01 | The United States Of America As Represented By The Department Of Health And Human Services | Intrinsic inhibitors of aldose reductase |
| US6117869A (en) * | 1998-08-04 | 2000-09-12 | Warner-Lambert Company | Compounds for and methods of inhibiting matrix metalloproteinases |
| US6607550B1 (en) | 2001-09-06 | 2003-08-19 | Anodyne Therapeutics, L.L.C. | Method of treating neuropathy using a photo energy device |
| MX354256B (es) | 2007-05-10 | 2018-02-20 | Avalon Pharmaceuticals | Derivados de fluoreno, antraceno, xanteno, dibenzosuberona y acridina y usos de ellos. |
| WO2013033046A2 (en) * | 2011-08-26 | 2013-03-07 | Gyula Vigh | Fluorescent pl markers for isoelectric focusing separations and fluorescent labeling |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1485648A (fr) * | 1966-05-06 | 1967-06-23 | Procédé pour la préparation de sulfamides | |
| US3655470A (en) * | 1969-03-29 | 1972-04-11 | Toa Gosei Chem Ind | Process for the production of a foamed thermoplastic resin sheet |
| US3849565A (en) * | 1972-01-12 | 1974-11-19 | Syntex Inc | Disubstituted xanthone carboxylic acid compounds for inhibiting asthma |
| CA1072359A (en) * | 1974-10-08 | 1980-02-26 | Hiroyuki Konishi | Method for controlling the growth of plants |
| US4232040A (en) * | 1978-03-08 | 1980-11-04 | Syntex (U.S.A.) Inc. | Compositions for and a method of preventing diabetic complications |
-
1987
- 1987-09-16 IT IT21930/87A patent/IT1223302B/it active
-
1988
- 1988-09-14 AT AT88115001T patent/ATE106399T1/de not_active IP Right Cessation
- 1988-09-14 EP EP88115001A patent/EP0307879B1/en not_active Expired - Lifetime
- 1988-09-14 DE DE3889820T patent/DE3889820T2/de not_active Expired - Fee Related
- 1988-09-15 AU AU22276/88A patent/AU618551B2/en not_active Ceased
- 1988-09-15 CA CA000577438A patent/CA1332062C/en not_active Expired - Fee Related
- 1988-09-16 US US07/245,165 patent/US4927849A/en not_active Expired - Fee Related
- 1988-09-16 ZA ZA886935A patent/ZA886935B/xx unknown
- 1988-09-16 JP JP63230214A patent/JP2596986B2/ja not_active Expired - Lifetime
-
1990
- 1990-02-08 US US07/476,762 patent/US5066676A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA886935B (en) | 1989-08-30 |
| DE3889820T2 (de) | 1995-01-12 |
| CA1332062C (en) | 1994-09-20 |
| AU618551B2 (en) | 1992-01-02 |
| ATE106399T1 (de) | 1994-06-15 |
| JPH01110663A (ja) | 1989-04-27 |
| JP2596986B2 (ja) | 1997-04-02 |
| US5066676A (en) | 1991-11-19 |
| US4927849A (en) | 1990-05-22 |
| DE3889820D1 (de) | 1994-07-07 |
| IT8721930A0 (it) | 1987-09-16 |
| EP0307879B1 (en) | 1994-06-01 |
| AU2227688A (en) | 1989-03-16 |
| EP0307879A3 (en) | 1990-07-04 |
| EP0307879A2 (en) | 1989-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970901 |