DK1451155T3 - Sammensætninger, metoder og kits i forbindelse med luminescerende forbindelser - Google Patents

Sammensætninger, metoder og kits i forbindelse med luminescerende forbindelser

Info

Publication number
DK1451155T3
DK1451155T3 DK02802815T DK02802815T DK1451155T3 DK 1451155 T3 DK1451155 T3 DK 1451155T3 DK 02802815 T DK02802815 T DK 02802815T DK 02802815 T DK02802815 T DK 02802815T DK 1451155 T3 DK1451155 T3 DK 1451155T3
Authority
DK
Denmark
Prior art keywords
kits
compositions
methods
luminescent compounds
heteroalkyl
Prior art date
Application number
DK02802815T
Other languages
English (en)
Inventor
Keith Wood
Erika Hawkins
Mike Scurria
Dieter Klaubert
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of DK1451155T3 publication Critical patent/DK1451155T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Decoration By Transfer Pictures (AREA)
  • Electroluminescent Light Sources (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK02802815T 2001-11-02 2002-11-01 Sammensætninger, metoder og kits i forbindelse med luminescerende forbindelser DK1451155T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/053,482 US7268229B2 (en) 2001-11-02 2001-11-02 Compounds to co-localize luminophores with luminescent proteins
PCT/US2002/034972 WO2003040100A1 (en) 2001-11-02 2002-11-01 Compositions, methods and kits pertaining to luminescent compounds

Publications (1)

Publication Number Publication Date
DK1451155T3 true DK1451155T3 (da) 2008-11-10

Family

ID=21984572

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02802815T DK1451155T3 (da) 2001-11-02 2002-11-01 Sammensætninger, metoder og kits i forbindelse med luminescerende forbindelser

Country Status (10)

Country Link
US (2) US7268229B2 (da)
EP (2) EP1451155B1 (da)
JP (1) JP4958388B2 (da)
CN (2) CN100439338C (da)
AT (1) ATE399784T1 (da)
CA (1) CA2462506C (da)
DE (1) DE60227408D1 (da)
DK (1) DK1451155T3 (da)
ES (1) ES2307829T3 (da)
WO (1) WO2003040100A1 (da)

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EP2323996B1 (en) 2008-08-18 2014-10-22 Promega Corporation Luminogenic compounds and methods to detect cytochrome p450 3a enzymes
JP5582505B2 (ja) 2009-02-09 2014-09-03 Ｊｎｃ株式会社 セレンテラジン類縁体及びその製造方法
DK2456864T3 (da) 2009-05-01 2015-12-21 Promega Corp Syntetiske oplophorus-luciferaser med forbedret lysemission
JP5605727B2 (ja) 2010-04-06 2014-10-15 Ｊｎｃ株式会社 セレンテラジン類縁体及びセレンテラミド類縁体
CN103038338B (zh) 2010-05-10 2017-03-08 加利福尼亚大学董事会 核糖核酸内切酶组合物及其使用方法
CN106148362B (zh) 2010-11-02 2021-04-30 普罗梅加公司 新型腔肠素底物及其使用方法
ES2543913T3 (es) 2010-11-02 2015-08-25 Promega Corporation Derivados de coelenterazina y métodos de uso de los mismos
US9273343B2 (en) 2011-09-02 2016-03-01 Promega Corporation Compounds and methods for assaying redox state of metabolically active cells and methods for measuring NAD(P)/NAD(P)H
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JP6040846B2 (ja) * 2013-04-08 2016-12-07 Jnc株式会社 セレンテラジン類縁体
JP6484987B2 (ja) 2013-10-21 2019-03-20 Jnc株式会社 エビルシフェラーゼの触媒蛋白質の変異遺伝子とその使用法
JP6442825B2 (ja) 2013-12-26 2018-12-26 Jnc株式会社 エビルシフェラーゼの触媒蛋白質の変異遺伝子とその使用法
EP3099691B1 (en) 2014-01-29 2019-11-20 Promega Corporation Pro-substrates for live cell applications
JP6703484B2 (ja) 2014-01-29 2020-06-03 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 細胞による取り込み測定のための、標識用試薬としての、キノンでマスクされたプローブ
JP6265020B2 (ja) 2014-04-16 2018-01-24 Jnc株式会社 エビルシフェラーゼの触媒蛋白質の変異遺伝子とその使用法
EP3191600A1 (en) * 2014-09-11 2017-07-19 Promega Corporation Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence
WO2016040835A1 (en) 2014-09-12 2016-03-17 Promega Corporation Internal protein tags
US9677117B2 (en) 2014-10-08 2017-06-13 Promega Corporation Bioluminescent succinate detection assay
JP6862368B2 (ja) 2015-06-25 2021-04-21 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ チエノピロール化合物、及びそのＯｐｌｏｐｈｏｒｕｓ由来ルシフェラーゼの阻害剤としての使用
EP4086261A1 (en) 2016-02-15 2022-11-09 Promega Corporation Process for the preparation of coelenterazine analogues
JP6978492B2 (ja) * 2016-09-09 2021-12-08 プロメガ コーポレイションPromega Corporation 二重保護されたプロセレンテラジン基質
EP4144738A1 (en) 2016-11-01 2023-03-08 Promega Corporation Coelenterazine analogues tethered to energy acceptors
JP7139330B2 (ja) 2016-12-01 2022-09-20 プロメガ コーポレイション 細胞不透過性セレンテラジンアナログ
JP7161475B2 (ja) 2016-12-28 2022-10-26 プロメガ コーポレイション 官能化ｎａｎｏｌｕｃ阻害剤
WO2019010094A1 (en) * 2017-07-06 2019-01-10 Promega Corporation STERILE SERIES PRO-COELENTERAZINE ANALOGS
EP3788048A1 (en) 2018-05-01 2021-03-10 Promega Corporation Coelenterazine compounds as nanoluc suicide substrates
US11390599B2 (en) 2018-06-01 2022-07-19 Promega Corporation Inhibitors of oplophorus luciferase-derived bioluminescent complexes
JP2021533102A (ja) 2018-07-27 2021-12-02 プロメガ コーポレイションPromega Corporation キノン含有複合体
KR20210072040A (ko) 2018-10-03 2021-06-16 프로메가 코포레이션 코엘렌테라진 및 이의 유사체 및 유도체를 안정화하기 위한 조성물 및 방법
AU2020392245A1 (en) 2019-11-27 2022-06-23 Promega Corporation Multipartite luciferase peptides and polypeptides
JP2023506486A (ja) 2019-12-10 2023-02-16 プロメガ コーポレイション 多官能性プローブを使用する生物発光検出用組成物及び生物発光検出方法
WO2021237118A2 (en) 2020-05-22 2021-11-25 Promega Corporation Enhancement of kinase target engagement
CN113683617B (zh) * 2021-07-16 2022-08-30 山东大学 一种基于腔肠素-h的氘代化合物及其制备方法与应用
US20240132859A1 (en) 2022-05-04 2024-04-25 Promega Corporation Modified dehalogenase with extended surface loop regions
US20240191211A1 (en) 2022-05-04 2024-06-13 Promega Corporation Bioluminescence-triggered photocatalytic labeling

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Also Published As

Publication number Publication date
JP4958388B2 (ja) 2012-06-20
EP1451155A4 (en) 2006-03-01
DE60227408D1 (de) 2008-08-14
US20080050760A1 (en) 2008-02-28
CA2462506C (en) 2010-04-06
EP1894933A3 (en) 2008-03-26
JP2005515977A (ja) 2005-06-02
US7268229B2 (en) 2007-09-11
CA2462506A1 (en) 2003-05-15
EP1451155B1 (en) 2008-07-02
CN101440089A (zh) 2009-05-27
EP1894933B1 (en) 2013-07-03
US20030153090A1 (en) 2003-08-14
CN100439338C (zh) 2008-12-03
WO2003040100A1 (en) 2003-05-15
EP1894933A2 (en) 2008-03-05
ES2307829T3 (es) 2008-12-01
EP1451155A1 (en) 2004-09-01
US7537912B2 (en) 2009-05-26
CN1612860A (zh) 2005-05-04
ATE399784T1 (de) 2008-07-15

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